Brief neuronal afterdischarges in the rat hippocampus lead to transient changes in oscillatory activity and to a very long-lasting decline in BOLD signals without inducing a hypoxic state.


Journal

NeuroImage
ISSN: 1095-9572
Titre abrégé: Neuroimage
Pays: United States
ID NLM: 9215515

Informations de publication

Date de publication:
15 12 2021
Historique:
received: 22 09 2021
revised: 24 11 2021
accepted: 29 11 2021
pubmed: 4 12 2021
medline: 22 2 2022
entrez: 3 12 2021
Statut: ppublish

Résumé

The effects of hippocampal neuronal afterdischarges (nAD) on hemodynamic parameters, such as blood-oxygen-level-dependent (BOLD) signals) and local cerebral blood volume (CBV) changes, as well as neuronal activity and metabolic parameters in the dentate gyrus, was investigated in rats by combining in vivo electrophysiology with functional magnetic resonance imaging (fMRI) or

Identifiants

pubmed: 34861394
pii: S1053-8119(21)01041-7
doi: 10.1016/j.neuroimage.2021.118769
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

118769

Informations de copyright

Copyright © 2021. Published by Elsevier Inc.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The author declares no competing financial interests

Auteurs

Alberto Arboit (A)

Functional Neuroimaging Group, Deutsches Zentrum für neurodegenerative Erkrankungen (DZNE), Leipzigerstr, 44, Magdeburg 39118, Germany.

Shih-Pi Ku (SP)

Department Functional Architecture of Memory, Leibniz Institute for Neurobiology (LIN), Magdeburg 39118, Germany.

Karla Krautwald (K)

Functional Neuroimaging Group, Deutsches Zentrum für neurodegenerative Erkrankungen (DZNE), Leipzigerstr, 44, Magdeburg 39118, Germany.

Frank Angenstein (F)

Functional Neuroimaging Group, Deutsches Zentrum für neurodegenerative Erkrankungen (DZNE), Leipzigerstr, 44, Magdeburg 39118, Germany; Department Functional Architecture of Memory, Leibniz Institute for Neurobiology (LIN), Magdeburg 39118, Germany; Center for Behavior and Brain Sciences (CBBS), Magdeburg, Germany; Medical Faculty, Otto von Guericke University, Magdeburg 39118, Germany. Electronic address: frank.angenstein@dzne.de.

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Classifications MeSH