COVID-19-associated mixed mold infection: A case report of aspergillosis and mucormycosis and a literature review.
Aspergillosis
COVID-19
Corticosteroids
Invasive fungal disease
Mucormycosis
SARS-CoV-2
Journal
Journal de mycologie medicale
ISSN: 1773-0449
Titre abrégé: J Mycol Med
Pays: France
ID NLM: 9425651
Informations de publication
Date de publication:
Mar 2022
Mar 2022
Historique:
received:
22
05
2021
revised:
02
11
2021
accepted:
25
11
2021
pubmed:
6
12
2021
medline:
31
3
2022
entrez:
5
12
2021
Statut:
ppublish
Résumé
COVID-19-associated mold infections have been increasingly reported, and the main entity is COVID-19-associated aspergillosis (CAPA). Similarly, COVID-19-associated mucormycosis has been reported in hematology, and its prevalence is high and has been increasing in the diabetic population in India during the third COVID-19 pandemic wave. Simultaneous infection with Mucorales and Aspergillus is rare and even rarer during COVID-19. Here, we report the case of a previously immunocompetent patient with severe SARS-CoV-2 infection complicated with probable CAPA and mucormycosis co-infection. Specific diagnostic tools for mucormycosis are lacking, and this case highlights the advantages of analyzing blood and respiratory samples using the quantitative polymerase chain reaction to detect these fungi. We further reviewed the literature on mixed Aspergillus/Mucorales invasive fungal diseases to provide an overview of patients presenting with both fungi and to identify characteristics of this rare infection.
Identifiants
pubmed: 34864498
pii: S1156-5233(21)00122-0
doi: 10.1016/j.mycmed.2021.101231
pmc: PMC8620017
pii:
doi:
Types de publication
Case Reports
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
101231Informations de copyright
Copyright © 2021 SFMM. Published by Elsevier Masson SAS. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors have nothing to declare
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