The influence of dietary intake of omega-3 polyunsaturated fatty acids on the association between short-term exposure to ambient nitrogen dioxide and respiratory and cardiovascular outcomes among healthy adults.
Air pollution
Cardiovascular
Lung function
Nitrogen dioxide
Omega-3 polyunsaturated fatty acids
Journal
Environmental health : a global access science source
ISSN: 1476-069X
Titre abrégé: Environ Health
Pays: England
ID NLM: 101147645
Informations de publication
Date de publication:
07 12 2021
07 12 2021
Historique:
received:
28
07
2021
accepted:
16
11
2021
entrez:
7
12
2021
pubmed:
8
12
2021
medline:
4
2
2022
Statut:
epublish
Résumé
Short-term exposure to ambient nitrogen dioxide (NO Sixty-two healthy participants were enrolled into low or high omega-3 groups based on their habitual omega-3 PUFA intake. Each participant was repeatedly assessed for lung function, blood lipids, markers of coagulation and fibrinolysis, vascular function, and heart rate variability (HRV) in up to five sessions, each separated by at least 7 days. This study was carried out in the Research Triangle area of North Carolina, USA between October 2016 and September 2019. Daily ambient NO The average concentration of ambient NO The results in this study imply that dietary omega-3 PUFA consumption may offer respiratory and vascular benefits in response to short-term exposure of healthy adults to NO ClinicalTrials.gov ( NCT02921048 ).
Sections du résumé
BACKGROUND
Short-term exposure to ambient nitrogen dioxide (NO
METHODS
Sixty-two healthy participants were enrolled into low or high omega-3 groups based on their habitual omega-3 PUFA intake. Each participant was repeatedly assessed for lung function, blood lipids, markers of coagulation and fibrinolysis, vascular function, and heart rate variability (HRV) in up to five sessions, each separated by at least 7 days. This study was carried out in the Research Triangle area of North Carolina, USA between October 2016 and September 2019. Daily ambient NO
RESULTS
The average concentration of ambient NO
CONCLUSIONS
The results in this study imply that dietary omega-3 PUFA consumption may offer respiratory and vascular benefits in response to short-term exposure of healthy adults to NO
TRIAL REGISTRATION
ClinicalTrials.gov ( NCT02921048 ).
Identifiants
pubmed: 34872587
doi: 10.1186/s12940-021-00809-9
pii: 10.1186/s12940-021-00809-9
pmc: PMC8650256
doi:
Substances chimiques
Air Pollutants
0
Fatty Acids, Unsaturated
0
Particulate Matter
0
Nitrogen Dioxide
S7G510RUBH
Banques de données
ClinicalTrials.gov
['NCT02921048']
Types de publication
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
123Subventions
Organisme : u.s. environmental protection agency
ID : U.S. Environmental Protection Agency Intramural Research Program
Informations de copyright
© 2021. The Author(s).
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