Mutations That Affect the Surface Expression of TRPV6 Are Associated with the Upregulation of Serine Proteases in the Placenta of an Infant.


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
24 Nov 2021
Historique:
received: 05 11 2021
revised: 18 11 2021
accepted: 22 11 2021
entrez: 10 12 2021
pubmed: 11 12 2021
medline: 18 12 2021
Statut: epublish

Résumé

Recently, we reported a case of an infant with neonatal severe under-mineralizing skeletal dysplasia caused by mutations within both alleles of the

Identifiants

pubmed: 34884497
pii: ijms222312694
doi: 10.3390/ijms222312694
pmc: PMC8657554
pii:
doi:

Substances chimiques

Calcium Channels 0
Proteome 0
TRPV Cation Channels 0
TRPV6 protein, human 0
Trpv6 protein, mouse 0
High-Temperature Requirement A Serine Peptidase 1 EC 3.4.21.-
HTRA1 protein, human EC 3.4.21.-
CTSG protein, human EC 3.4.21.20
Cathepsin G EC 3.4.21.20

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Deutsche Forschungsgemeinschaft
ID : FE629/2 WE4866/1- 1 SFB894/P2

Références

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Auteurs

Claudia Fecher-Trost (C)

Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Buildings 61.4 and 46, 66421 Homburg, Germany.

Karin Wolske (K)

Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Buildings 61.4 and 46, 66421 Homburg, Germany.

Christine Wesely (C)

Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Buildings 61.4 and 46, 66421 Homburg, Germany.

Heidi Löhr (H)

Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Buildings 61.4 and 46, 66421 Homburg, Germany.

Daniel S Klawitter (DS)

Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Buildings 61.4 and 46, 66421 Homburg, Germany.

Petra Weissgerber (P)

Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Buildings 61.4 and 46, 66421 Homburg, Germany.
Transgenic Technologies, Center for Molecular Signaling (PZMS), Saarland University, Building 61.4, 66421 Homburg, Germany.

Elise Gradhand (E)

Kinder- und Perinatalpathologie Dr. Senckenberg, Institut für Pathologie Universitätsklinikum Frankfurt/Main Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.

Christine P Burren (CP)

Department of Translational Health Sciences, Bristol Medical School, University of Bristol, University Hospitals Bristol and Weston NHS Foundation Trust, Upper Maudlin St, Bristol BS2 8BJ, UK.

Anna E Mason (AE)

Histopathology Department, Aneurin Bevan University Health Board, Royal Gwent Hospital, Cardiff NP20 2UB, UK.

Manuel Winter (M)

Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Buildings 61.4 and 46, 66421 Homburg, Germany.

Ulrich Wissenbach (U)

Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Buildings 61.4 and 46, 66421 Homburg, Germany.

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Classifications MeSH