Association of mental demands in the workplace with cognitive function in older adults at increased risk for dementia.


Journal

BMC geriatrics
ISSN: 1471-2318
Titre abrégé: BMC Geriatr
Pays: England
ID NLM: 100968548

Informations de publication

Date de publication:
10 12 2021
Historique:
received: 26 07 2021
accepted: 23 11 2021
entrez: 11 12 2021
pubmed: 12 12 2021
medline: 11 1 2022
Statut: epublish

Résumé

Growing evidence suggests a protective effect of high mental demands at work on cognitive function in later life. However, evidence on corresponding associations in older adults at increased risk for dementia is currently lacking. This study investigates the association between mental demands at work and cognitive functioning in the population of the AgeWell.de-trial. Cross-sectional investigation of the association between global cognitive functioning (Montreal Cognitive Assessment) and mental demands at work in older individuals at increased risk for dementia (Cardiovascular Risk Factors, Aging, and Incidence of Dementia (CAIDE)score ≥ 9; n = 941, age: 60-77 years). Occupational information was matched to Occupational Information Network (O*NET)-descriptors. Associations between cognitive function and O*NET-indices executive, verbal and novelty were investigated using generalized linear models. Higher values of index verbal (b = .69, p = .002) were associated with better cognitive function when adjusting for covariates. No association was observed for indices executive (b = .37, p = .062) and novelty (b = .45, p = .119). Higher education, younger age, and employment were linked to better cognitive function, while preexisting medical conditions did not change the associations. Higher levels of depressive symptomatology were associated with worse cognitive function. Higher levels of verbal demands at work were associated with better cognitive function for older adults with increased dementia risk. This suggests an advantage for older persons in jobs with high mental demands even after retirement and despite prevalent risk factors. Longitudinal studies are warranted to confirm these results and evaluate the potential of workplaces to prevent cognitive decline through increased mental demands.

Identifiants

pubmed: 34893023
doi: 10.1186/s12877-021-02653-5
pii: 10.1186/s12877-021-02653-5
pmc: PMC8665567
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

688

Informations de copyright

© 2021. The Author(s).

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Auteurs

Andrea E Zülke (AE)

Institute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, 04103, Leipzig, Germany. andrea.zuelke@medizin.uni-leipzig.de.

Melanie Luppa (M)

Institute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, 04103, Leipzig, Germany.

Susanne Röhr (S)

Institute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, 04103, Leipzig, Germany.
Global Brain Health Institute (GBHI), Trinity College Dublin, D02 PN40, Dublin, Ireland.

Marina Weißenborn (M)

Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, 69120, Heidelberg, Germany.

Alexander Bauer (A)

Institute of General Practice and Family Medicine, Martin-Luther-University Halle-Wittenberg, 06112, Halle (Saale), Germany.

Franziska-Antonia Zora Samos (FZ)

Institute of General Practice and Family Medicine, Martin-Luther-University Halle-Wittenberg, 06112, Halle (Saale), Germany.

Flora Kühne (F)

Institute of General Practice/Family Medicine, University Hospital of LMU Munich, 80336, Munich, Germany.

Isabel Zöllinger (I)

Institute of General Practice/Family Medicine, University Hospital of LMU Munich, 80336, Munich, Germany.

Juliane Döhring (J)

Institute of General Practice, University of Kiel, 24105, Kiel, Germany.

Christian Brettschneider (C)

Department of Health Economics and Health Service Research, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany.

Anke Oey (A)

Institute for General Practice, Work Group Medical Statistics and IT-Infrastructure, Hannover Medical School, 30625, Hannover, Germany.

David Czock (D)

Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, 69120, Heidelberg, Germany.

Thomas Frese (T)

Institute of General Practice and Family Medicine, Martin-Luther-University Halle-Wittenberg, 06112, Halle (Saale), Germany.

Jochen Gensichen (J)

Institute of General Practice/Family Medicine, University Hospital of LMU Munich, 80336, Munich, Germany.

Walter E Haefeli (WE)

Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, 69120, Heidelberg, Germany.

Wolfgang Hoffmann (W)

Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), site Rostock/ Greifswald, 17489, Greifswald, Germany.
Institute of Community Medicine, Dept. of Epidemiology of Health Care and Community Health, University Medicine Greifswald, 17487, Greifswald, Germany.

Hanna Kaduszkiewicz (H)

Institute of General Practice, University of Kiel, 24105, Kiel, Germany.

Hans-Helmut König (HH)

Department of Health Economics and Health Service Research, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany.

Jochen René Thyrian (JR)

Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), site Rostock/ Greifswald, 17489, Greifswald, Germany.
Institute of Community Medicine, Dept. of Epidemiology of Health Care and Community Health, University Medicine Greifswald, 17487, Greifswald, Germany.

Birgitt Wiese (B)

Institute for General Practice, Work Group Medical Statistics and IT-Infrastructure, Hannover Medical School, 30625, Hannover, Germany.

Steffi G Riedel-Heller (SG)

Institute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, 04103, Leipzig, Germany.

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