Prevention of preterm birth in twin pregnancies.
17-hydroxyprogesterone
cerclage
pessary
preterm birth
transvaginal cervical length
twin pregnancy
vaginal progesterone
Journal
American journal of obstetrics & gynecology MFM
ISSN: 2589-9333
Titre abrégé: Am J Obstet Gynecol MFM
Pays: United States
ID NLM: 101746609
Informations de publication
Date de publication:
03 2022
03 2022
Historique:
received:
21
06
2021
revised:
01
11
2021
accepted:
03
12
2021
pubmed:
14
12
2021
medline:
23
4
2022
entrez:
13
12
2021
Statut:
ppublish
Résumé
Twins represent 3.2% of all live births; however, they account for 20.0% of all preterm deliveries, with 60.0% and 10.7% of twins delivered before 37 and 32 weeks' gestation, respectively. Twin pregnancies have 5 times higher risk of early neonatal and infant death related to prematurity. Monochorionic twins have a higher incidence of both indicated and spontaneous preterm delivery than dichorionic twins. Transvaginal ultrasound of the cervical length before 24 weeks' gestation is the best tool to predict preterm birth, independent of other risk factors. Among all evaluated therapies to decrease or prevent preterm birth in twin pregnancies, the use of vaginal progesterone in women with a transvaginal cervical length of <25 mm decreased neonatal morbidity, and physical examination-indicated cerclage in women with a cervical dilation of >1 cm showed a significant decrease in preterm birth at different gestational ages and perinatal mortality.
Identifiants
pubmed: 34896357
pii: S2589-9333(21)00247-0
doi: 10.1016/j.ajogmf.2021.100551
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
100551Informations de copyright
Copyright © 2021. Published by Elsevier Inc.