Bifunctional conducting polymer matrices with antibacterial and neuroprotective effects.

Polymers
Antibacterial coating Conducting polymer Neural interface Neuroprotective effect Poly(3,4-ethylenedioxypyrrole) Tetracycline

Journal

Bioelectrochemistry (Amsterdam, Netherlands)
ISSN: 1878-562X
Titre abrégé: Bioelectrochemistry
Pays: Netherlands
ID NLM: 100953583

Informations de publication

Date de publication:
Apr 2022
Historique:
received: 23 08 2021
revised: 24 10 2021
accepted: 29 11 2021
pubmed: 14 12 2021
medline: 3 3 2022
entrez: 13 12 2021
Statut: ppublish

Résumé

Current trends in the field of neural tissue engineering include the design of advanced biomaterials combining excellent electrochemical performance with versatile biological characteristics. The purpose of this work was to develop an antibacterial and neuroprotective coating based on a conducting polymer - poly(3,4-ethylenedioxypyrrole) (PEDOP), loaded with an antibiotic agent - tetracycline (Tc). Employing an electrochemical technique to immobilize Tc within a growing polymer matrix allowed to fabricate robust PEDOP/Tc coatings with a high charge storage capacity (63.65 ± 6.05 mC/cm

Identifiants

DOI: 10.1016/j.bioelechem.2021.108030 PMID: 34896782
pubmed: 34896782
pii: S1567-5394(21)00293-0
doi: 10.1016/j.bioelechem.2021.108030
pii:
doi:

Substances chimiques

Polymers 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

108030

Informations de copyright

Copyright © 2021 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Dominika Czerwińska-Główka (D)

Department of Physical Chemistry and Technology of Polymers, Silesian University of Technology, M.Strzody 9, 44-100 Gliwice, Poland.

Magdalena Skonieczna (M)

Department of Systems Biology and Engineering, Faculty of Automatic Control, Electronics and Computer Science, Silesian University of Technology, Akademicka 16, 44-100 Gliwice, Poland; Biotechnology Centre, Silesian University of Technology, B. Krzywoustego 8, 44-100 Gliwice, Poland.

Adrian Barylski (A)

Institute of Materials Engineering, University of Silesia, 75 Pulku Piechoty, 41-500 Chorzow, Poland.

Sylwia Golba (S)

Institute of Materials Engineering, University of Silesia, 75 Pulku Piechoty, 41-500 Chorzow, Poland.

Wioletta Przystaś (W)

Biotechnology Centre, Silesian University of Technology, B. Krzywoustego 8, 44-100 Gliwice, Poland; Department of Air Protection, Faculty of Energy and Environmental Engineering, Silesian University of Technology, S. Konarskiego 22B, 44-100 Gliwice, Poland.

Ewa Zabłocka-Godlewska (E)

Biotechnology Centre, Silesian University of Technology, B. Krzywoustego 8, 44-100 Gliwice, Poland; Department of Air Protection, Faculty of Energy and Environmental Engineering, Silesian University of Technology, S. Konarskiego 22B, 44-100 Gliwice, Poland.

Sebastian Student (S)

Department of Systems Biology and Engineering, Faculty of Automatic Control, Electronics and Computer Science, Silesian University of Technology, Akademicka 16, 44-100 Gliwice, Poland; Biotechnology Centre, Silesian University of Technology, B. Krzywoustego 8, 44-100 Gliwice, Poland.

Beata Cwalina (B)

Biotechnology Centre, Silesian University of Technology, B. Krzywoustego 8, 44-100 Gliwice, Poland; Department of Environmental Biotechnology, Faculty of Energy and Environmental Engineering, Silesian University of Technology, S.Konarskiego 18, 44-100 Gliwice, Poland.

Katarzyna Krukiewicz (K)

Department of Physical Chemistry and Technology of Polymers, Silesian University of Technology, M.Strzody 9, 44-100 Gliwice, Poland. Electronic address: katarzyna.krukiewicz@polsl.pl.

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Classifications MeSH

questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Polymères › Bifunctional conducting polymer matrices with...