New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources.
Saccharomyces Genome Database
Saccharomyces cerevisiae
Alliance of Genome Resources
knowledgebase
reference genome
Journal
Genetics
ISSN: 1943-2631
Titre abrégé: Genetics
Pays: United States
ID NLM: 0374636
Informations de publication
Date de publication:
04 04 2022
04 04 2022
Historique:
received:
15
09
2021
accepted:
11
11
2021
pubmed:
14
12
2021
medline:
8
4
2022
entrez:
13
12
2021
Statut:
ppublish
Résumé
Saccharomyces cerevisiae is used to provide fundamental understanding of eukaryotic genetics, gene product function, and cellular biological processes. Saccharomyces Genome Database (SGD) has been supporting the yeast research community since 1993, serving as its de facto hub. Over the years, SGD has maintained the genetic nomenclature, chromosome maps, and functional annotation, and developed various tools and methods for analysis and curation of a variety of emerging data types. More recently, SGD and six other model organism focused knowledgebases have come together to create the Alliance of Genome Resources to develop sustainable genome information resources that promote and support the use of various model organisms to understand the genetic and genomic bases of human biology and disease. Here we describe recent activities at SGD, including the latest reference genome annotation update, the development of a curation system for mutant alleles, and new pages addressing homology across model organisms as well as the use of yeast to study human disease.
Identifiants
pubmed: 34897464
pii: 6460340
doi: 10.1093/genetics/iyab224
pmc: PMC9209811
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NHGRI NIH HHS
ID : U24 HG001315
Pays : United States
Organisme : NHGRI NIH HHS
ID : U24 HG010859
Pays : United States
Organisme : NHGRI NIH HHS
ID : U41 HG002273
Pays : United States
Informations de copyright
© The Author(s) 2021. Published by Oxford University Press on behalf of Genetics Society of America.
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