Predicting the individual probability of macular hole closure following intravitreal ocriplasmin injections for vitreomacular traction release using baseline characteristics.
Aged
Aged, 80 and over
Female
Fibrinolysin
/ administration & dosage
Forecasting
Humans
Intravitreal Injections
Male
Middle Aged
Peptide Fragments
/ administration & dosage
Probability
Retinal Perforations
/ drug therapy
Retrospective Studies
Treatment Outcome
Vitrectomy
/ methods
Vitreous Detachment
/ complications
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
16 12 2021
16 12 2021
Historique:
received:
15
05
2021
accepted:
01
12
2021
entrez:
17
12
2021
pubmed:
18
12
2021
medline:
27
1
2022
Statut:
epublish
Résumé
The primary objective was to create and establish a new formula that predicts the individual probability of macular hole closure for eyes with full thickness macular holes (FTMH) accompanied by vitreomacular traction (VMT) which received enzymatic vitreolysis using intravitreally administered ocriplasmin. The secondary objective was to evaluate the forecast reliability of a previously published formula for VMT resolution in VMT-only eyes (Odds
Identifiants
pubmed: 34916576
doi: 10.1038/s41598-021-03509-z
pii: 10.1038/s41598-021-03509-z
pmc: PMC8677762
doi:
Substances chimiques
Peptide Fragments
0
microplasmin
7V6HE3DM5A
Fibrinolysin
EC 3.4.21.7
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
24096Informations de copyright
© 2021. The Author(s).
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