Resveratrol treatment does not reduce arterial inflammation in males at risk of type 2 diabetes: a randomized crossover trial.

Eine Behandlung mit Resveratrol führt nicht zu einer Reduktion der arteriellen Entzündung bei Männern mit einem erhöhten Risiko für Typ-2-Diabetes: Eine randomisierte Crossover-Studie.

Journal

Nuklearmedizin. Nuclear medicine
ISSN: 2567-6407
Titre abrégé: Nuklearmedizin
Pays: Germany
ID NLM: 7609387

Informations de publication

Date de publication:
Feb 2022
Historique:
pubmed: 18 12 2021
medline: 9 2 2022
entrez: 17 12 2021
Statut: ppublish

Résumé

Resveratrol has shown promising anti-inflammatory effects in in vitro and animal studies. We aimed to investigate this effect on arterial inflammation in vivo. This was an additional analysis of a double-blind randomized crossover trial which included eight male subjects with decreased insulin sensitivity who underwent an Arterial Resveratrol failed to attenuate arterial or systemic inflammation as measured with ZIEL: Resveratrol hat in In-vitro- und Tierstudien vielversprechende anti-inflammatorische Effekte gezeigt. Unser Ziel war es, diese Wirkung auf die arterielle Entzündung in vivo zu untersuchen. Es handelte sich um eine zusätzliche Analyse einer randomisierten Doppelblind-Crossover-Studie, an der acht männliche Probanden mit verminderter Insulinsensitivität teilnahmen, die sich nach 34 Tagen Placebo- und Resveratrol-Behandlung (150 mg/Tag) einer Die arterielle Resveratrol konnte die mittels

Autres résumés

Type: Publisher (ger)
ZIEL: Resveratrol hat in In-vitro- und Tierstudien vielversprechende anti-inflammatorische Effekte gezeigt. Unser Ziel war es, diese Wirkung auf die arterielle Entzündung in vivo zu untersuchen.

Identifiants

pubmed: 34918332
doi: 10.1055/a-1585-7215
doi:

Substances chimiques

Radiopharmaceuticals 0
Fluorodeoxyglucose F18 0Z5B2CJX4D
Resveratrol Q369O8926L

Types de publication

Journal Article Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Pagination

33-41

Informations de copyright

Thieme. All rights reserved.

Déclaration de conflit d'intérêts

Disclosures: Joachim E. Wildberger receives institutional grants from Agfa, Morstel, Belgium; Bayer Healthcare, Berlin, Germany; GE, Chicago, Illinois; Optimed, Ettlingen, Germany; Philips Healthcare, Best, the Netherlands; Siemens Healthineers, Forchheim, Germany, and personal fees from the speaker’s bureau of Bayer Healthcare, Berlin, Germany and Siemens Healthineers, Forchheim, Germany. Ellen Boswijk, Marlies de Ligt, Marie-Fleur J. Habets, Alma M.A. Mingels, Wouter D. van Marken Lichtenbelt, Felix M. Mottaghy, Patrick Schrauwen and Jan Bucerius, have no relationships with industry currently or within the last two years. Conflicts of interest: All authors declare that they have no conflict of interest regarding the research presented in this manuscript.

Auteurs

Ellen Boswijk (E)

Department of Radiology and Nuclear Medicine, Maastricht UMC+, Maastricht, Netherlands.
Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, Netherlands.

Marlies de Ligt (M)

Department of Nutrition and Movement Sciences, School of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, Netherlands.

Marie-Fleur J Habets (MJ)

Department of Nutrition and Movement Sciences, School of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, Netherlands.

Alma M A Mingels (AMA)

Department of Clinical Chemistry, Central Diagnostic Laboratory, Maastricht UMC+, Maastricht, Netherlands.

Wouter D van Marken Lichtenbelt (WD)

Department of Nutrition and Movement Sciences, School of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, Netherlands.

Felix M Mottaghy (FM)

Department of Radiology and Nuclear Medicine, Maastricht UMC+, Maastricht, Netherlands.
Department of Nuclear Medicine, University Hospital Aachen, Aachen, Germany.

Patrick Schrauwen (P)

Department of Nutrition and Movement Sciences, School of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, Netherlands.

Joachim E Wildberger (JE)

Department of Radiology and Nuclear Medicine, Maastricht UMC+, Maastricht, Netherlands.
Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, Netherlands.

Jan Bucerius (J)

Department of Radiology and Nuclear Medicine, Maastricht UMC+, Maastricht, Netherlands.
Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, Netherlands.
Department of Nuclear Medicine, Universitätsmedizin Göttingen, Gottingen, Germany.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH