Normal Values of Left Ventricular Size and Function on Three-Dimensional Echocardiography: Results of the World Alliance Societies of Echocardiography Study.
3D echocardiography
Ejection fraction
Left ventricle
Strain
WASE
Journal
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
ISSN: 1097-6795
Titre abrégé: J Am Soc Echocardiogr
Pays: United States
ID NLM: 8801388
Informations de publication
Date de publication:
05 2022
05 2022
Historique:
received:
30
09
2021
revised:
29
11
2021
accepted:
07
12
2021
pubmed:
18
12
2021
medline:
10
5
2022
entrez:
17
12
2021
Statut:
ppublish
Résumé
Echocardiography remains the most widely used modality to assess left ventricular (LV) chamber size and function. Currently this assessment is most frequently performed using two-dimensional (2D) echocardiography. However, three-dimensional (3D) echocardiography has been shown to be more accurate and reproducible than 2D echocardiography. Current normative reference values for 3D LV analysis are based predominantly on data from North America and Europe. The World Alliance Societies of Echocardiography study was designed to sample normal subjects from around the world to provide more universal global reference ranges. The aim of this study was to assess the worldwide feasibility of LV 3D echocardiography and report on size and functional measurements. A total of 2,262 healthy subjects were prospectively enrolled from 19 centers in 15 countries. Three-dimensional LV full-volume data sets were obtained and analyzed offline using vendor-neutral software. Measurements included LV end-diastolic and end-systolic volumes, LV ejection fraction (LVEF), global longitudinal strain (GLS), and global circumferential strain. Results were categorized by age (18-40, 41-65, and >65 years), sex, and race. A total of 1,589 subjects (feasibility 70%) had adequate LV data sets for analysis. Mean normal values for indexed end-diastolic volume, end-systolic volume, and LVEF in men and women were 70 ± 15 and 65 ± 12 mL/m Age, sex, and race should be considered when defining normal reference values for LV dimension and functional parameters obtained by 3D echocardiography.
Sections du résumé
BACKGROUND
Echocardiography remains the most widely used modality to assess left ventricular (LV) chamber size and function. Currently this assessment is most frequently performed using two-dimensional (2D) echocardiography. However, three-dimensional (3D) echocardiography has been shown to be more accurate and reproducible than 2D echocardiography. Current normative reference values for 3D LV analysis are based predominantly on data from North America and Europe. The World Alliance Societies of Echocardiography study was designed to sample normal subjects from around the world to provide more universal global reference ranges. The aim of this study was to assess the worldwide feasibility of LV 3D echocardiography and report on size and functional measurements.
METHODS
A total of 2,262 healthy subjects were prospectively enrolled from 19 centers in 15 countries. Three-dimensional LV full-volume data sets were obtained and analyzed offline using vendor-neutral software. Measurements included LV end-diastolic and end-systolic volumes, LV ejection fraction (LVEF), global longitudinal strain (GLS), and global circumferential strain. Results were categorized by age (18-40, 41-65, and >65 years), sex, and race.
RESULTS
A total of 1,589 subjects (feasibility 70%) had adequate LV data sets for analysis. Mean normal values for indexed end-diastolic volume, end-systolic volume, and LVEF in men and women were 70 ± 15 and 65 ± 12 mL/m
CONCLUSIONS
Age, sex, and race should be considered when defining normal reference values for LV dimension and functional parameters obtained by 3D echocardiography.
Identifiants
pubmed: 34920112
pii: S0894-7317(21)00867-1
doi: 10.1016/j.echo.2021.12.004
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
449-459Investigateurs
Aldo D Prado
(AD)
Eduardo Filipini
(E)
Agatha Kwon
(A)
Samantha Hoschke-Edwards
(S)
Tania Regina Afonso
(TR)
Babitha Thampinathan
(B)
Maala Sooriyakanthan
(M)
Tiangang Zhu
(T)
Zhilong Wang
(Z)
Yingbin Wang
(Y)
Lixue Yin
(L)
Shuang Li
(S)
R Alagesan
(R)
S Balasubramanian
(S)
R V A Ananth
(RVA)
Manish Bansal
(M)
Luigi Badano
(L)
Eduardo Bossone
(E)
Davide Di Vece
(D)
Michele Bellino
(M)
Tomoko Nakao
(T)
Takayuki Kawata
(T)
Megumi Hirokawa
(M)
Naoko Sawada
(N)
Yousuke Nabeshima
(Y)
Hye Rim Yun
(HR)
Ji-Won Hwang
(JW)
Commentaires et corrections
Type : CommentIn
Informations de copyright
Copyright © 2021 American Society of Echocardiography. Published by Elsevier Inc. All rights reserved.