Imaging features to distinguish AQP4-positive NMOSD and MS at disease onset: A retrospective analysis in a single-center cohort.

AQP4+ neuromyelitis optica spectrum disorders Diagnostic criteria MRI Multiple sclerosis Real-life

Journal

European journal of radiology
ISSN: 1872-7727
Titre abrégé: Eur J Radiol
Pays: Ireland
ID NLM: 8106411

Informations de publication

Date de publication:
Jan 2022
Historique:
received: 11 09 2021
revised: 17 11 2021
accepted: 18 11 2021
pubmed: 19 12 2021
medline: 4 1 2022
entrez: 18 12 2021
Statut: ppublish

Résumé

To compare the diagnostic performance of imaging criteria that differentiate AQP4 We retrospectively analyzed MRI scans at DO (defined as the first 60 days of patient-reported symptom onset) in 10 AQP4 The Matthews criteria were met in 20% of AQP4 While diagnostic MRI criteria were developed on data acquired years after disease onset, our study demonstrates their high applicability at the earliest disease stages, thus emphasising their valuable use in clinical practice.

Identifiants

pubmed: 34922119
pii: S0720-048X(21)00544-1
doi: 10.1016/j.ejrad.2021.110063
pii:
doi:

Substances chimiques

Aquaporin 4 0
Autoantibodies 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

110063

Informations de copyright

Copyright © 2021. Published by Elsevier B.V.

Auteurs

Tobias Zrzavy (T)

Department of Neurology, Medical University of Vienna, Vienna, Austria.

Fritz Leutmezer (F)

Department of Neurology, Medical University of Vienna, Vienna, Austria.

Paulus Rommer (P)

Department of Neurology, Medical University of Vienna, Vienna, Austria.

Gabriel Bsteh (G)

Department of Neurology, Medical University of Vienna, Vienna, Austria.

Barbara Kornek (B)

Department of Neurology, Medical University of Vienna, Vienna, Austria.

Thomas Berger (T)

Department of Neurology, Medical University of Vienna, Vienna, Austria.

Daniela Prayer (D)

Department of Biomedical Imaging and Image Guided Therapy, Medical University of Vienna, Vienna, Austria.

Majda Thurnher (M)

Department of Biomedical Imaging and Image Guided Therapy, Medical University of Vienna, Vienna, Austria.

Lukas Haider (L)

Department of Biomedical Imaging and Image Guided Therapy, Medical University of Vienna, Vienna, Austria; NMR Research Unit, Queens Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Science, University College London, Austria. Electronic address: lukas.haider@meduniwien.ac.at.

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Classifications MeSH