Comparison of outcome and characteristics between 6343 COVID-19 patients and 2256 other community-acquired viral pneumonia patients admitted to Dutch ICUs.
COVID-19
Coronavirus
Critical care
Intensive care
Mortality
Outcome
Pneumonia
Journal
Journal of critical care
ISSN: 1557-8615
Titre abrégé: J Crit Care
Pays: United States
ID NLM: 8610642
Informations de publication
Date de publication:
Apr 2022
Apr 2022
Historique:
received:
12
01
2021
revised:
12
10
2021
accepted:
05
12
2021
pubmed:
21
12
2021
medline:
17
3
2022
entrez:
20
12
2021
Statut:
ppublish
Résumé
Describe the differences in characteristics and outcomes between COVID-19 and other viral pneumonia patients admitted to Dutch ICUs. Data from the National-Intensive-Care-Evaluation-registry of COVID-19 patients admitted between February 15th and January 1th 2021 and other viral pneumonia patients admitted between January 1st 2017 and January 1st 2020 were used. Patients' characteristics, the unadjusted, and adjusted in-hospital mortality were compared. 6343 COVID-19 and 2256 other viral pneumonia patients from 79 ICUs were included. The COVID-19 patients included more male (71.3 vs 49.8%), had a higher Body-Mass-Index (28.1 vs 25.5), less comorbidities (42.2 vs 72.7%), and a prolonged hospital length of stay (19 vs 9 days). The COVID-19 patients had a significantly higher crude in-hospital mortality rate (Odds ratio (OR) = 1.80), after adjustment for patient characteristics and ICU occupancy rate the OR was respectively 3.62 and 3.58. Higher mortality among COVID-19 patients could not be explained by patient characteristics and higher ICU occupancy rates, indicating that COVID-19 is more severe compared to other viral pneumonia. Our findings confirm earlier warnings of a high need of ICU capacity and high mortality rates among relatively healthy COVID-19 patients as this may lead to a higher mental workload for the staff.
Identifiants
pubmed: 34929530
pii: S0883-9441(21)00278-1
doi: 10.1016/j.jcrc.2021.12.007
pmc: PMC8683137
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
76-82Investigateurs
D P Verbiest
(DP)
L F Te Velde
(LF)
E M van Driel
(EM)
T Rijpstra
(T)
P W G Elbers
(PWG)
A P I Houwink
(API)
L Georgieva
(L)
E Verweij
(E)
R M de Jong
(RM)
F M van Iersel
(FM)
T J J Koning
(TJJ)
E Rengers
(E)
N Kusadasi
(N)
M L Erkamp
(ML)
R van den Berg
(R)
C J M G Jacobs
(CJMG)
J L Epker
(JL)
A A Rijkeboer
(AA)
M T de Bruin
(MT)
P Spronk
(P)
A Draisma
(A)
D J Versluis
(DJ)
A E van den Berg
(AE)
M Vrolijk-de Mos
(MV)
J A Lens
(JA)
R V Pruijsten
(RV)
H Kieft
(H)
J Rozendaal
(J)
F Nooteboom
(F)
D P Boer
(DP)
I T A Janssen
(ITA)
L van Gulik
(L)
M P Koetsier
(MP)
V M Silderhuis
(VM)
R M Schnabel
(RM)
I Drogt
(I)
W de Ruijter
(W)
R J Bosman
(RJ)
T Frenzel
(T)
L C Urlings-Strop
(LC)
A Dijkhuizen
(A)
I Z Hené
(IZ)
A R de Meijer
(AR)
J W M Holtkamp
(JWM)
N Postma
(N)
A J G H Bindels
(AJGH)
R M J Wesselink
(RMJ)
E R van Slobbe-Bijlsma
(ER)
P H J van der Voort
(PHJ)
B J W Eikemans
(BJW)
D J Mehagnoul-Schipper
(DJ)
D Gommers
(D)
J G Lutisan
(JG)
M Hoeksema
(M)
M G W Barnas
(MGW)
B Festen-Spanjer
(B)
M van Lieshout
(M)
N C Gritters
(NC)
M van Tellingen
(M)
G B Brunnekreef
(GB)
J Vandeputte
(J)
T P J Dormans
(TPJ)
M E Hoogendoorn
(ME)
M de Graaff
(M)
D Moolenaar
(D)
A C Reidinga
(AC)
J J Spijkstra
(JJ)
R de Waal
(R)
Informations de copyright
Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest All authors state that there were no conflict of interest. The NICE foundation pays the department of Medical Informatics to process and analyze data for the registry. This institution is not paid specifically for this study but it is part of the task agreement to perform analyses like this on data from the NICE registry.
Références
Crit Care. 2020 May 6;24(1):198
pubmed: 32375845
Int J Epidemiol. 2015 Dec;44(6):1850-1850h
pubmed: 26613713
Front Immunol. 2021 Feb 03;12:602848
pubmed: 33613574
JAMA. 2020 Apr 28;323(16):1612-1614
pubmed: 32191259
BMC Med. 2021 Aug 30;19(1):213
pubmed: 34461893
Intensive Care Med. 2020 Nov;46(11):2035-2047
pubmed: 33034689
Crit Care Med. 2021 Jul 1;49(7):e701-e706
pubmed: 33861555
Radiology. 2020 Aug;296(2):E97-E104
pubmed: 32339082
Lancet. 2020 Feb 15;395(10223):497-506
pubmed: 31986264
Lancet Respir Med. 2020 May;8(5):506-517
pubmed: 32272080
Lancet Respir Med. 2020 May;8(5):475-481
pubmed: 32105632
Crit Care Med. 2006 May;34(5):1297-310
pubmed: 16540951
JAMA Intern Med. 2020 Oct 1;180(10):1345-1355
pubmed: 32667669
JAMA. 2020 Apr 28;323(16):1574-1581
pubmed: 32250385
Ann Am Thorac Soc. 2021 Jul;18(7):1202-1210
pubmed: 33544045
J Infect. 2020 Jun;80(6):656-665
pubmed: 32283155
BMJ. 2020 Mar 26;368:m1211
pubmed: 32217624
Crit Care Med. 2020 Aug;48(8):1196-1202
pubmed: 32697491
Int J Infect Dis. 2021 Feb;103:316-322
pubmed: 33279652
Psychiatr Prax. 2020 May;47(4):190-197
pubmed: 32340048