Comparison of magnetic resonance imaging and computed tomography for bone assessment of neurogenic heterotopic ossification of the hip: a preliminary study.


Journal

Journal of orthopaedic surgery and research
ISSN: 1749-799X
Titre abrégé: J Orthop Surg Res
Pays: England
ID NLM: 101265112

Informations de publication

Date de publication:
20 Dec 2021
Historique:
received: 05 10 2021
accepted: 05 12 2021
entrez: 21 12 2021
pubmed: 22 12 2021
medline: 26 3 2022
Statut: epublish

Résumé

Neurogenic heterotopic ossification (NHO) is a frequent complication, often involving the hip. The functional impact may require surgical management and pre-surgical imaging assessment is necessary, usually by computed tomography (CT). We aimed to compare the performances of magnetic resonance imaging (MRI) and CT for bone assessment on pre-surgical imaging of the heterotopic ossifications and their features in NHO of the hip. This single-center prospective preliminary study included all patients who underwent surgery for NHO with joint limitation from July 2019 to March 2020. All patients had a CT after biphasic iodinated solution injection and an MRI including T1-weighted, STIR and ZTE sequences. Standardized reports were completed for both exams for each patient, evaluating location, implantation and fragmentation of NHO, relation to the joint capsule and bone mineralization, then were compared. Seven patients from 32 to 70 years old (mean = 50.2 ± 17.2 years) were evaluated. NHO were bilateral in 2 patients, for a total of nine hips: six right hips and three left hips. Observed concordance rates between MRI and CT were, respectively, 94.4% for location, 100% for circumferential extension, 87.3% for implantation 88.9% for fragmentation, 77.8% for relation to the joint capsule and 66.7% for bone mineralization. It was 100% for femoral neck fracture and osteonecrosis of the femoral head. This preliminary study suggests that pre-surgical MRI imaging should be considered as effective as CT for bone assessment of NHO and their features. ClinicalTrials.gov, NCT03832556. Registered February 6, 2019, https://clinicaltrials.gov/ct2/show/NCT03832556 .

Sections du résumé

BACKGROUND BACKGROUND
Neurogenic heterotopic ossification (NHO) is a frequent complication, often involving the hip. The functional impact may require surgical management and pre-surgical imaging assessment is necessary, usually by computed tomography (CT). We aimed to compare the performances of magnetic resonance imaging (MRI) and CT for bone assessment on pre-surgical imaging of the heterotopic ossifications and their features in NHO of the hip.
METHODS METHODS
This single-center prospective preliminary study included all patients who underwent surgery for NHO with joint limitation from July 2019 to March 2020. All patients had a CT after biphasic iodinated solution injection and an MRI including T1-weighted, STIR and ZTE sequences. Standardized reports were completed for both exams for each patient, evaluating location, implantation and fragmentation of NHO, relation to the joint capsule and bone mineralization, then were compared.
RESULTS RESULTS
Seven patients from 32 to 70 years old (mean = 50.2 ± 17.2 years) were evaluated. NHO were bilateral in 2 patients, for a total of nine hips: six right hips and three left hips. Observed concordance rates between MRI and CT were, respectively, 94.4% for location, 100% for circumferential extension, 87.3% for implantation 88.9% for fragmentation, 77.8% for relation to the joint capsule and 66.7% for bone mineralization. It was 100% for femoral neck fracture and osteonecrosis of the femoral head.
CONCLUSION CONCLUSIONS
This preliminary study suggests that pre-surgical MRI imaging should be considered as effective as CT for bone assessment of NHO and their features.
TRIAL REGISTRATION BACKGROUND
ClinicalTrials.gov, NCT03832556. Registered February 6, 2019, https://clinicaltrials.gov/ct2/show/NCT03832556 .

Identifiants

pubmed: 34930354
doi: 10.1186/s13018-021-02869-6
pii: 10.1186/s13018-021-02869-6
pmc: PMC8686225
doi:

Banques de données

ClinicalTrials.gov
['NCT03832556']

Types de publication

Comparative Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

725

Informations de copyright

© 2021. The Author(s).

Références

J Magn Reson Imaging. 2020 Apr;51(4):975-992
pubmed: 31709670
BMC Musculoskelet Disord. 2016 Oct 18;17(1):433
pubmed: 27756329
PLoS One. 2017 Mar 15;12(3):e0173995
pubmed: 28296979
HSS J. 2015 Jul;11(2):123-9
pubmed: 26140031
J Bone Joint Surg Br. 2005 Mar;87(3):301-5
pubmed: 15773634
Calcif Tissue Int. 2021 Feb;108(2):196-206
pubmed: 33044630
Radiology. 2018 Mar;286(3):960-966
pubmed: 29117482
Top Magn Reson Imaging. 2010 Oct;21(5):275-89
pubmed: 22129641
Spine (Phila Pa 1976). 2018 Jul 1;43(13):928-933
pubmed: 29095415
Skeletal Radiol. 2012 Jan;41(1):61-6
pubmed: 21331512
Insights Imaging. 2013 Oct;4(5):595-603
pubmed: 23828230
J Bone Joint Surg Br. 2009 Nov;91(11):1493-8
pubmed: 19880896
Eur Radiol. 2005 Sep;15(9):1867-75
pubmed: 15856244
Orthop Traumatol Surg Res. 2018 Feb;104(1S):S121-S127
pubmed: 29174871

Auteurs

Raphaël Amar (R)

Department of Radiology, Assistance Publique - Hôpitaux de Paris (AP-HP), DMU Start Imaging, Raymond Poincaré Teaching Hospital, Garches, France. raphael.amar@aphp.fr.

Tristan Thiry (T)

Department of Radiology, Assistance Publique - Hôpitaux de Paris (AP-HP), DMU Start Imaging, Raymond Poincaré Teaching Hospital, Garches, France.

Marjorie Salga (M)

Department of Physical Medicine and Rehabilitation, Assistance Publique - Hôpitaux de Paris (AP-HP), Raymond Poincaré Teaching Hospital, CIC 1429, Garches, France.
UVSQ, INSERM U1179, END-ICAP, University of Paris-Saclay, Montigny-le-Bretonneux, France.
Group for Research in Neuro-Orthopedics From Garches (GRENOG), Garches, France.

Dominique Safa (D)

Department of Radiology, Assistance Publique - Hôpitaux de Paris (AP-HP), DMU Start Imaging, Raymond Poincaré Teaching Hospital, Garches, France.

Annaëlle Chetrit (A)

Department of Radiology, Assistance Publique - Hôpitaux de Paris (AP-HP), DMU Start Imaging, Raymond Poincaré Teaching Hospital, Garches, France.

Laure Gatin (L)

UVSQ, INSERM U1179, END-ICAP, University of Paris-Saclay, Montigny-le-Bretonneux, France.
Group for Research in Neuro-Orthopedics From Garches (GRENOG), Garches, France.
Department of Orthopaedic and Trauma Surgery, Assistance Publique - Hôpitaux de Paris (AP-HP), Raymond Poincaré Teaching Hospital, Garches, France.

Robert-Yves Carlier (RY)

Department of Radiology, Assistance Publique - Hôpitaux de Paris (AP-HP), DMU Start Imaging, Raymond Poincaré Teaching Hospital, Garches, France.
UVSQ, INSERM U1179, END-ICAP, University of Paris-Saclay, Montigny-le-Bretonneux, France.

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Classifications MeSH