Structural variation of the 3-acetamido-4,5,6-trihydroxyazepane iminosugar through epimerization and

Acetylglucosaminidase / antagonists & inhibitors Alkylation Enzyme Inhibitors / chemical synthesis Escherichia coli / enzymology Humans Imino Sugars / chemical synthesis Molecular Conformation beta-N-Acetylhexosaminidases / antagonists & inhibitors

Journal

Organic & biomolecular chemistry
ISSN: 1477-0539
Titre abrégé: Org Biomol Chem
Pays: England
ID NLM: 101154995

Informations de publication

Date de publication:
19 01 2022
Historique:
pubmed: 24 12 2021
medline: 15 3 2022
entrez: 23 12 2021
Statut: epublish

Résumé

We report the synthesis of seven-membered iminosugars derived from a 3

Identifiants

DOI: 10.1039/d1ob02280f PMID: 34940771
pubmed: 34940771
doi: 10.1039/d1ob02280f
doi:

Substances chimiques

Enzyme Inhibitors 0
Imino Sugars 0
Acetylglucosaminidase EC 3.2.1.52
beta-N-Acetylhexosaminidases EC 3.2.1.52

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

619-629

Auteurs

J Bouquet (J)

Université de Poitiers, IC2MP, UMR CNRS 7285, OrgaSynth Team, Glyco group, 4 rue Michel Brunet, 86073 Poitiers cedex 09, France. yves.bleriot@univ-poitiers.fr.

N Auberger (N)

Université de Poitiers, IC2MP, UMR CNRS 7285, OrgaSynth Team, Glyco group, 4 rue Michel Brunet, 86073 Poitiers cedex 09, France. yves.bleriot@univ-poitiers.fr.
ORCID: 0000-0002-2076-2112

R Ashmus (R)

Department of Chemistry, Simon Fraser University, 8888 University Drive, Burnaby, British Columbia, V5S 1P6, Canada. dvocadlo@sfu.ca.

D King (D)

Department of Chemistry, Simon Fraser University, 8888 University Drive, Burnaby, British Columbia, V5S 1P6, Canada. dvocadlo@sfu.ca.

A Bordes (A)

Université de Poitiers, IC2MP, UMR CNRS 7285, OrgaSynth Team, Glyco group, 4 rue Michel Brunet, 86073 Poitiers cedex 09, France. yves.bleriot@univ-poitiers.fr.

N Fontelle (N)

Université de Poitiers, IC2MP, UMR CNRS 7285, OrgaSynth Team, Glyco group, 4 rue Michel Brunet, 86073 Poitiers cedex 09, France. yves.bleriot@univ-poitiers.fr.

S Nakagawa (S)

Department of Hospital Pharmacy, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan. kato@med.u-toyama.ac.jp.

Z Madden (Z)

Department of Chemistry, Simon Fraser University, 8888 University Drive, Burnaby, British Columbia, V5S 1P6, Canada. dvocadlo@sfu.ca.

C Proceviat (C)

Department of Chemistry, Simon Fraser University, 8888 University Drive, Burnaby, British Columbia, V5S 1P6, Canada. dvocadlo@sfu.ca.

A Kato (A)

Department of Hospital Pharmacy, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan. kato@med.u-toyama.ac.jp.
ORCID: 0000-0001-8022-196X

J Désiré (J)

Université de Poitiers, IC2MP, UMR CNRS 7285, OrgaSynth Team, Glyco group, 4 rue Michel Brunet, 86073 Poitiers cedex 09, France. yves.bleriot@univ-poitiers.fr.
ORCID: 0000-0003-1076-3610

D J Vocadlo (DJ)

Department of Chemistry, Simon Fraser University, 8888 University Drive, Burnaby, British Columbia, V5S 1P6, Canada. dvocadlo@sfu.ca.
ORCID: 0000-0001-6897-5558

Y Blériot (Y)

Université de Poitiers, IC2MP, UMR CNRS 7285, OrgaSynth Team, Glyco group, 4 rue Michel Brunet, 86073 Poitiers cedex 09, France. yves.bleriot@univ-poitiers.fr.
ORCID: 0000-0002-3209-9282

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Glycosidases › Hexosaminidases › beta-N-Acetylhexosaminidases › Acetylglucosaminidase › Structural variation of the...
questionsmedicales.fr › Métabolisme › Alkylation › Structural variation of the...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Mécanismes moléculaires de l'action pharmacologique › Antienzymes › Structural variation of the...
questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Enterobacteriaceae › Escherichia › Escherichia coli › Structural variation of the...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Structural variation of the...
questionsmedicales.fr › Glucides › Iminosucres › Structural variation of the...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Structural variation of the...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Glycosidases › Hexosaminidases › beta-N-Acetylhexosaminidases › Structural variation of the...