Epilepsia partialis continua in relapsing-remitting multiple sclerosis: A possible distinct relapse phenotype.
Demyelination
Epilepsia partialis continua
Focal motor status epilepticus
Multiple sclerosis
Relapsing-remitting
Journal
Clinical neurology and neurosurgery
ISSN: 1872-6968
Titre abrégé: Clin Neurol Neurosurg
Pays: Netherlands
ID NLM: 7502039
Informations de publication
Date de publication:
02 2022
02 2022
Historique:
received:
14
08
2021
revised:
05
10
2021
accepted:
15
12
2021
pubmed:
28
12
2021
medline:
5
4
2022
entrez:
27
12
2021
Statut:
ppublish
Résumé
Epilepsia partialis continua (EPC) is a rare phenomenon in multiple sclerosis (MS). We describe a patient with relapsing-remitting MS and three episodes of EPC, with refractoriness to anti-seizure drugs but corticosteroid-responsiveness. No lesions likely attributable to her episodes of EPC were seen on 1.5 Tesla MRI, which we hypothesize was due to the small volume of presumed cortical/juxtacortical lesions involving the primary motor cortex. The association with relapsing-remitting disease, corticosteroid responsiveness, and dissemination of episodes of EPC in both space and time in our patient suggest that EPC may represent a distinct relapse phenotype in MS.
Identifiants
pubmed: 34959105
pii: S0303-8467(21)00628-4
doi: 10.1016/j.clineuro.2021.107099
pii:
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
107099Informations de copyright
Copyright © 2021 Elsevier B.V. All rights reserved.