Characterization of cardiac amyloidosis using cardiac magnetic resonance fingerprinting.


Journal

International journal of cardiology
ISSN: 1874-1754
Titre abrégé: Int J Cardiol
Pays: Netherlands
ID NLM: 8200291

Informations de publication

Date de publication:
15 Mar 2022
Historique:
received: 04 09 2021
revised: 26 11 2021
accepted: 20 12 2021
pubmed: 30 12 2021
medline: 15 3 2022
entrez: 29 12 2021
Statut: ppublish

Résumé

Cardiac amyloidosis (CA) is an infiltrative cardiomyopathy with poor prognosis absent appropriate treatment. Elevated native myocardial T Nine CA patients and five controls were scanned at 3 T using a prospectively gated cMRF acquisition. Two cMRF-based analysis approaches were examined: (1) relaxometric-based linear discriminant analysis (LDA) using native T Elevated myocardial T These findings suggest that cMRF may be a valuable technique for the detection and characterization of CA. Analysis of cMRF signal timecourse data may improve tissue characterization as compared to analysis of native T

Sections du résumé

BACKGROUND BACKGROUND
Cardiac amyloidosis (CA) is an infiltrative cardiomyopathy with poor prognosis absent appropriate treatment. Elevated native myocardial T
METHODS METHODS
Nine CA patients and five controls were scanned at 3 T using a prospectively gated cMRF acquisition. Two cMRF-based analysis approaches were examined: (1) relaxometric-based linear discriminant analysis (LDA) using native T
RESULTS RESULTS
Elevated myocardial T
CONCLUSIONS CONCLUSIONS
These findings suggest that cMRF may be a valuable technique for the detection and characterization of CA. Analysis of cMRF signal timecourse data may improve tissue characterization as compared to analysis of native T

Identifiants

pubmed: 34963645
pii: S0167-5273(21)02041-6
doi: 10.1016/j.ijcard.2021.12.038
pmc: PMC8857016
mid: NIHMS1767246
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

107-110

Subventions

Organisme : NHLBI NIH HHS
ID : R01 HL094557
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL126827
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL146754
Pays : United States

Informations de copyright

Copyright © 2021 Elsevier B.V. All rights reserved.

Références

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pubmed: 32078075
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pubmed: 31762101
Prog Nucl Magn Reson Spectrosc. 2021 Feb;122:11-22
pubmed: 33632415
Magn Reson Med Sci. 2019 Jan 10;18(1):96-104
pubmed: 29794408
Circ Cardiovasc Imaging. 2020 May;13(5):e009901
pubmed: 32408830
J Cardiovasc Magn Reson. 2018 Aug 16;20(1):58
pubmed: 30115079
Magn Reson Imaging. 2008 Oct;26(8):1160-6
pubmed: 18513908
J Magn Reson Imaging. 2020 Oct;52(4):1044-1052
pubmed: 32222092
Brain Struct Funct. 2022 Jan;227(1):313-329
pubmed: 34697684

Auteurs

Brendan L Eck (BL)

Imaging Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA. Electronic address: eckb@ccf.org.

Nicole Seiberlich (N)

Department of Radiology, Department of Biomedical Engineering, University of Michigan, 1150 West Medical Center Drive, Ann Arbor, MI 48109, USA.

Scott D Flamm (SD)

Imaging Institute, Heart, Vascular, and Thoracic Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

Jesse I Hamilton (JI)

Department of Radiology, Department of Biomedical Engineering, University of Michigan, 1150 West Medical Center Drive, Ann Arbor, MI 48109, USA.

Abhilash Suresh (A)

Heart, Vascular, and Thoracic Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

Yash Kumar (Y)

Heart, Vascular, and Thoracic Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

Mazen Hanna (M)

Heart, Vascular, and Thoracic Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

Angel Houston (A)

Imaging Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

Derrek Tew (D)

Imaging Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

W H Wilson Tang (WHW)

Heart, Vascular, and Thoracic Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

Deborah H Kwon (DH)

Imaging Institute, Heart, Vascular, and Thoracic Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

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Classifications MeSH