Effect of Alpha-Fetoprotein on Differentiation of Myeloid Supressor Cells.

Cell Differentiation HLA-DR Antigens Humans Lymphocyte Activation Myeloid Cells Recombinant Proteins / pharmacology alpha-Fetoproteins
alpha-fetoprotein (AFP) immune tolerance myeloid-derived suppressor cells (MDSC) pregnancy

Journal

Doklady. Biochemistry and biophysics
ISSN: 1608-3091
Titre abrégé: Dokl Biochem Biophys
Pays: United States
ID NLM: 101126895

Informations de publication

Date de publication:
Nov 2021
Historique:
received: 30 04 2021
accepted: 07 09 2021
revised: 06 09 2021
entrez: 30 12 2021
pubmed: 31 12 2021
medline: 12 2 2022
Statut: ppublish

Résumé

The effect of recombinant alpha-fetoprotein (AFP) on human myeloid suppressor cell (MDSC) differentiation was studied in vitro in the presence of cytokines IL-6 (10 ng/mL) and GM-CSF (10 ng/mL). It was found that AFP at concentrations of 50 and 100 IU/mL increased the number of MDSC (CD33

Identifiants

DOI: 10.1134/S1607672921060077 PMID: 34966967
pubmed: 34966967
doi: 10.1134/S1607672921060077
pii: 10.1134/S1607672921060077
doi:

Substances chimiques

HLA-DR Antigens 0
Recombinant Proteins 0
alpha-Fetoproteins 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

434-437

Informations de copyright

© 2021. Pleiades Publishing, Ltd.

Références

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doi: 10.1002/eji.201344200
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doi: 10.1007/s00262-017-2067-y
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Gagnon, A., Wilson, R.D., Audibert, F., Allen, V.M., Blight, C., Brock, J.A., Desilets, V.A., Johnson, J.A., Langlois, S., Summers, A., and Wyatt, P., Obstetrical complications associated with abnormal maternal serum markers analytes, J. Obstet. Gynaecol. Can., 2008, vol. 30, pp. 918–932.
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doi: 10.4155/fsoa-2018-0029 pubmed: 30652015 pmcid: 6331696

Auteurs

S A Zamorina (SA)

Institute of Ecology and Genetics of Microorganisms, Ural Branch of the Russian Academy of Sciences, Branch of the PFIC Ural Branch of the Russian Academy of Sciences, Perm, Russia. mantissa7@mail.ru.
Perm State National Research University, Perm, Russia. mantissa7@mail.ru.

K Yu Shardina (KY)

Institute of Ecology and Genetics of Microorganisms, Ural Branch of the Russian Academy of Sciences, Branch of the PFIC Ural Branch of the Russian Academy of Sciences, Perm, Russia.

V P Timganova (VP)

Institute of Ecology and Genetics of Microorganisms, Ural Branch of the Russian Academy of Sciences, Branch of the PFIC Ural Branch of the Russian Academy of Sciences, Perm, Russia.

M S Bochkova (MS)

Institute of Ecology and Genetics of Microorganisms, Ural Branch of the Russian Academy of Sciences, Branch of the PFIC Ural Branch of the Russian Academy of Sciences, Perm, Russia.
Perm State National Research University, Perm, Russia.

S V Uzhviyuk (SV)

Institute of Ecology and Genetics of Microorganisms, Ural Branch of the Russian Academy of Sciences, Branch of the PFIC Ural Branch of the Russian Academy of Sciences, Perm, Russia.

M B Raev (MB)

Institute of Ecology and Genetics of Microorganisms, Ural Branch of the Russian Academy of Sciences, Branch of the PFIC Ural Branch of the Russian Academy of Sciences, Perm, Russia.
Perm State National Research University, Perm, Russia.

V A Chereshnev (VA)

Institute of Ecology and Genetics of Microorganisms, Ural Branch of the Russian Academy of Sciences, Branch of the PFIC Ural Branch of the Russian Academy of Sciences, Perm, Russia.
Perm State National Research University, Perm, Russia.

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Classifications MeSH

questionsmedicales.fr › Phénomènes physiologiques cellulaires › Différenciation cellulaire › Effect of Alpha-Fetoprotein on Differentiation...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Isoantigènes › Antigènes d'histocompatibilité › Antigènes HLA › Antigènes HLA-D › Antigènes HLA-DR › Effect of Alpha-Fetoprotein on Differentiation...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Effect of Alpha-Fetoprotein on Differentiation...
questionsmedicales.fr › Phénomènes du système immunitaire › Activation des lymphocytes › Effect of Alpha-Fetoprotein on Differentiation...
questionsmedicales.fr › Cellules › Cellules myéloïdes › Effect of Alpha-Fetoprotein on Differentiation...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines recombinantes › Effect of Alpha-Fetoprotein on Differentiation...
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Marqueurs biologiques tumoraux › Alphafoetoprotéines › Effect of Alpha-Fetoprotein on Differentiation...