Association between urinary bisphenol A concentrations and semen quality: A meta-analytic study.
Endocrine disruptors
Meta-analysis
Pollution
Polycarbonate plastics
Sperm motility
Spermatozoa
Journal
Biochemical pharmacology
ISSN: 1873-2968
Titre abrégé: Biochem Pharmacol
Pays: England
ID NLM: 0101032
Informations de publication
Date de publication:
03 2022
03 2022
Historique:
received:
13
11
2021
revised:
15
12
2021
accepted:
16
12
2021
pubmed:
31
12
2021
medline:
3
3
2022
entrez:
30
12
2021
Statut:
ppublish
Résumé
Although preclinical research has revealed disrupting effects on male reproductive functions of bisphenol A (BPA), as yet clinical studies have led to inconsistent results. The present meta‑analysis aims to establish the existence and the extent of the association between BPA exposure and semen quality. A thorough search of PubMed, Scopus and Web of Science databases was carried out. Only studies reporting data from multivariable linear regression analyses (β-coefficients with 95% CI), assessing the association between urinary levels of BPA and standard semen parameters were included. Nine studies provided information about an overall sample of 2,399 men. Only the negative association between urinary BPA levels and sperm motility reached statistical significance (pooled β-coefficient = -0.82; 95% CI: -1.51 to -0.12, p = 0.02; P
Identifiants
pubmed: 34968490
pii: S0006-2952(21)00522-0
doi: 10.1016/j.bcp.2021.114896
pii:
doi:
Substances chimiques
Benzhydryl Compounds
0
Biomarkers
0
Estrogens, Non-Steroidal
0
Phenols
0
bisphenol A
MLT3645I99
Types de publication
Journal Article
Meta-Analysis
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
114896Informations de copyright
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