Diseases with oral manifestations among adult asthmatics in Finland: a population-based matched cohort study.
Asthma
EPIDEMIOLOGY
ORAL MEDICINE
PUBLIC HEALTH
Journal
BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874
Informations de publication
Date de publication:
31 12 2021
31 12 2021
Historique:
entrez:
1
1
2022
pubmed:
2
1
2022
medline:
8
3
2022
Statut:
epublish
Résumé
Many comorbidities are associated with adult asthma and may exacerbate the asthma burden of disease. This study aims to investigate the risk for major oral diseases or oral-manifesting diseases in asthmatic compared with non-asthmatic adults. We conducted a population-based matched cohort study with a 13.8-year follow-up. A baseline questionnaire was completed by participants in 1997 and follow-up data were extracted from the national hospital discharge registry of the National Institute for Health and Welfare in Finland from 1997 to 2014. A total of 1394 adults with asthma were matched with 2398 adults without asthma based on sex, age and area of residence. Asthmatic adults were identified from the Drug Reimbursement Register of the Finnish Social Insurance Institution based on a special drug reimbursement right resulting from asthma. Participants without asthma were identified from the Population Register. Oral health-related primary diagnoses were retrieved using codes from the International Classification of Diseases, 10th edition and divided into groups of diseases. Cox's proportional hazards models stratified by matching unit and models matched and adjusted for pack-years, education level and body mass index (when possible) were used to evaluate the matched and further adjusted HRs for diseases comparing asthmatic and non-asthmatic cohorts. Adult asthma was associated with a higher risk for any oral-manifesting disease (adjusted HR 1.41, 95% CI 1.11 to 1.80), herpes zoster (adjusted HR 6.18, 95% CI 1.21 to 31.6), benign tumours of the oral cavity and pharynx (matched HR 1.94, 95% CI 1.05 to 3.56) and dermatological diseases (pemphigus, pemphigoid, dermatitis herpetiformis, psoriasis and lichen planus, HR 1.67, 95% CI 1.01 to 2.78). In this study, adult asthmatics experienced a higher risk for a major oral disease or oral-manifesting disease.
Identifiants
pubmed: 34972766
pii: bmjopen-2021-053133
doi: 10.1136/bmjopen-2021-053133
pmc: PMC8720978
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e053133Informations de copyright
© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
Références
J Pak Med Assoc. 2015 Nov;65(11):1226-7
pubmed: 26564298
J Am Acad Dermatol. 2017 Mar;76(3):377-390
pubmed: 28212759
J Allergy Clin Immunol. 2019 Jul;144(1):1-12
pubmed: 31277742
Eur Respir Rev. 2013 Mar 1;22(127):44-52
pubmed: 23457164
Prim Dent J. 2018 Mar 1;7(1):48-57
pubmed: 29609671
Genes (Basel). 2019 Jan 23;10(2):
pubmed: 30678091
N Y State Dent J. 2012 Apr;78(3):14-8
pubmed: 22803270
J Allergy Clin Immunol. 2016 May;137(5):1406-12
pubmed: 26739414
Allergy Asthma Proc. 2018 Mar 1;39(2):103-109
pubmed: 29490768
BMJ Case Rep. 2014 Oct 19;2014:
pubmed: 25331144
NPJ Prim Care Respir Med. 2019 Apr 29;29(1):14
pubmed: 31036820
Adv Immunol. 2017;135:1-52
pubmed: 28826527
Mediators Inflamm. 2015;2015:819194
pubmed: 26783384
Allergy. 2018 Jul;73(7):1479-1488
pubmed: 29461632
F1000Res. 2018 Sep 24;7:
pubmed: 30345002
Open Forum Infect Dis. 2020 Jan 09;7(1):ofaa005
pubmed: 32010734
Chest. 2020 Mar;157(3):516-528
pubmed: 31678077
Epidemiology. 2010 Jan;21(1):13-5
pubmed: 20010207
Am J Respir Crit Care Med. 2010 Feb 15;181(4):315-23
pubmed: 19892860
Infect Dis Clin North Am. 2017 Dec;31(4):811-826
pubmed: 29079160
Expert Rev Respir Med. 2011 Jun;5(3):377-93
pubmed: 21702660
Am J Respir Crit Care Med. 2008 Aug 1;178(3):218-224
pubmed: 18480428
Lancet. 2015 Sep 5;386(9997):983-94
pubmed: 26025581
Oral Dis. 2018 Apr;24(3):442-448
pubmed: 28833877
Atlas Oral Maxillofac Surg Clin North Am. 2017 Sep;25(2):113-126
pubmed: 28778301
Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 Oct;120(4):e183-9
pubmed: 25944682
J Allergy Clin Immunol. 2005 Nov;116(5):1123-8
pubmed: 16275386
Arch Oral Biol. 2015 Apr;60(4):667-74
pubmed: 25443979
J Allergy Clin Immunol. 2017 Oct;140(4):909-920
pubmed: 28987220
Int J Dent. 2016;2016:7278925
pubmed: 27781066
Scand J Dent Res. 1991 Jun;99(3):212-8
pubmed: 1871531
Clin Transl Allergy. 2018 May 4;8:13
pubmed: 29755730
Am J Epidemiol. 2011 Sep 15;174(6):631-41
pubmed: 21828369
J Clin Periodontol. 1984 Feb;11(2):132-7
pubmed: 6583212
Expert Rev Respir Med. 2016;10(1):39-51
pubmed: 26610152
J Allergy Clin Immunol. 2018 Apr;141(4):1169-1179
pubmed: 29627041
Lancet. 2018 Feb 24;391(10122):783-800
pubmed: 29273246
J Asthma. 2017 Apr;54(3):250-257
pubmed: 27410999
Clin Mol Allergy. 2020 Nov 7;18(1):22
pubmed: 33292326
Medicine (Baltimore). 2020 Jul 31;99(31):e21534
pubmed: 32756203
J Asthma Allergy. 2018 Feb 09;11:19-27
pubmed: 29445292
Aust Dent J. 2010 Jun;55(2):128-33
pubmed: 20604752
Respir Care. 2020 Aug;65(8):1211-1220
pubmed: 32156792
Front Pediatr. 2019 Jun 25;7:256
pubmed: 31294006
Br J Dermatol. 2015 Jun;172(6):1660-1661
pubmed: 25533772
Clin Exp Allergy. 2017 Oct;47(10):1246-1252
pubmed: 28665552
J Investig Allergol Clin Immunol. 2018;28(2):91-97
pubmed: 29345235