Validity of the γ-Ray Evaluation with iodoamphetamine for Cerebral Blood Flow Assessment (REICA) method for quantification of cerebral blood flow including acetazolamide challenge test.


Journal

Annals of nuclear medicine
ISSN: 1864-6433
Titre abrégé: Ann Nucl Med
Pays: Japan
ID NLM: 8913398

Informations de publication

Date de publication:
Mar 2022
Historique:
received: 02 10 2021
accepted: 17 11 2021
pubmed: 2 1 2022
medline: 5 4 2022
entrez: 1 1 2022
Statut: ppublish

Résumé

The γ-Ray Evaluation with iodoamphetamine for Cerebral Blood Flow Assessment (REICA) is a new method for quantifying cerebral blood flow (CBF) using single-photon emission computed tomography (SPECT) and [ The REICA and Graph-Plot (GP) methods were used to calculate mean CBF (mCBF) for 92 acquisitions (rest: 57, stress: 35) and cerebrovascular reactivity (CVR) in 33 patients. To obtain stress data, 15 mg/kg of acetazolamide was injected intravenously 10 min before the administration of For mCBF, the correlation coefficients (r) were 0.792 for the REICA method and 0.636 for the GP method. For CVR, r values were 0.660 for the REICA method and 0.578 for the GP method. In both acquisitions, the REICA method had a stronger correlation with the ARG method than the GP method. For mCBF, there was a significant difference in the correlation coefficient between the two correlation coefficients (p < 0.01). The REICA method was more accurate than the GP method in quantifying CBF and closer to the ARG method. The REICA method, which is a noninvasive method of cerebral blood flow quantification using

Identifiants

pubmed: 34973145
doi: 10.1007/s12149-021-01700-w
pii: 10.1007/s12149-021-01700-w
pmc: PMC8897379
doi:

Substances chimiques

Radiopharmaceuticals 0
Iofetamine C2A5X08042
Acetazolamide O3FX965V0I

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

279-284

Subventions

Organisme : CSRD VA
ID : 1
Pays : United States
Organisme : Nihon Medi-Physics
ID : 2
Organisme : CSRD VA
ID : 1
Pays : United States

Informations de copyright

© 2021. The Author(s).

Références

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Auteurs

Yoshiaki Miyazaki (Y)

Department of Radiology, National Hospital Organization Kyushu Medical Center, 1-8-1, Jigyohama, Chuo-Ku, Fukuoka-City, Fukuoka, 810-8563, Japan. yomiyaza@ncc.go.jp.
Department of Radiological Technology, Radiological Diagnosis, National Cancer Center, 5-1-1, Tsukiji, Chuo-Ku, Tokyo, 104-0045, Japan. yomiyaza@ncc.go.jp.

Masashi Kameyama (M)

Department of Diagnostic Radiology, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, 35-2 Sakae-Cho, Itabashi-Ku, Tokyo, 173-0015, Japan.

Akira Nakamizo (A)

Department of Neurosurgery, Clinical Research Institute, National Hospital Organization Kyushu Medical Center, 1-8-1, Jigyohama, Chuo-Ku, Fukuoka-City, Fukuoka, 810-8563, Japan.

Tomoyuki Noguchi (T)

Department of Radiology, National Hospital Organization Kyushu Medical Center, 1-8-1, Jigyohama, Chuo-Ku, Fukuoka-City, Fukuoka, 810-8563, Japan.

Nobuyuki Tabata (N)

Department of Radiology, National Hospital Organization Kyushu Medical Center, 1-8-1, Jigyohama, Chuo-Ku, Fukuoka-City, Fukuoka, 810-8563, Japan.

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