A comparison of changes in bone turnover markers after gastric bypass and sleeve gastrectomy, and their association with markers of interest.
Bariatric surgery
Bone turnover markers
Roux-en-Y gastric bypass
Sclerostin
Sleeve gastrectomy
Journal
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
ISSN: 1878-7533
Titre abrégé: Surg Obes Relat Dis
Pays: United States
ID NLM: 101233161
Informations de publication
Date de publication:
Mar 2022
Mar 2022
Historique:
received:
01
09
2021
revised:
23
11
2021
accepted:
01
12
2021
pubmed:
3
1
2022
medline:
29
3
2022
entrez:
2
1
2022
Statut:
ppublish
Résumé
It is still debated whether differences in bone turnover markers (BTMs) exist between the 2 most popular bariatric surgery procedures (Roux-en-Y gastric bypass [RYGB] and sleeve gastrectomy [SG]). To compare changes in BTMs after RYGB and SG, and to investigate their association with predefined markers of interest. University hospital, Lille, France. An ancillary investigation of a prospective cohort was conducted. SG patients with severe obesity ≥40 years were matched one-to-one to RYGB patients for age, sex, body mass index (BMI), and menopausal status. BTMs, as well as predefined markers of interest, were measured at baseline, 12, and 24 months after bariatric surgery. Sixty-four patients (66% women) had a mean (standard deviation [SD]) age of 49.6 years (5.1) and a mean (SD) BMI of 45.0 kg/m RYGB was associated with a greater increase in BTMs than SG at 12 and 24 months.
Sections du résumé
BACKGROUND
BACKGROUND
It is still debated whether differences in bone turnover markers (BTMs) exist between the 2 most popular bariatric surgery procedures (Roux-en-Y gastric bypass [RYGB] and sleeve gastrectomy [SG]).
OBJECTIVES
OBJECTIVE
To compare changes in BTMs after RYGB and SG, and to investigate their association with predefined markers of interest.
SETTING
METHODS
University hospital, Lille, France.
METHODS
METHODS
An ancillary investigation of a prospective cohort was conducted. SG patients with severe obesity ≥40 years were matched one-to-one to RYGB patients for age, sex, body mass index (BMI), and menopausal status. BTMs, as well as predefined markers of interest, were measured at baseline, 12, and 24 months after bariatric surgery.
RESULTS
RESULTS
Sixty-four patients (66% women) had a mean (standard deviation [SD]) age of 49.6 years (5.1) and a mean (SD) BMI of 45.0 kg/m
CONCLUSION
CONCLUSIONS
RYGB was associated with a greater increase in BTMs than SG at 12 and 24 months.
Identifiants
pubmed: 34973928
pii: S1550-7289(21)00573-6
doi: 10.1016/j.soard.2021.12.004
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
373-383Informations de copyright
Copyright © 2021 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.