The Application of Crown-Chin Length to Crown-Rump Length Ratio in Predicting Fetal Skeletal Dysplasia at First Trimester.
crown chin length
first trimester
skeletal dysplasia
ultrasound
Journal
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
ISSN: 1550-9613
Titre abrégé: J Ultrasound Med
Pays: England
ID NLM: 8211547
Informations de publication
Date de publication:
Oct 2022
Oct 2022
Historique:
revised:
15
12
2021
received:
01
09
2021
accepted:
16
12
2021
pubmed:
4
1
2022
medline:
20
9
2022
entrez:
3
1
2022
Statut:
ppublish
Résumé
To examine the feasibility of using crown-chin length (CCL) to crown-rump length (CRL) ratio in screening for skeletal dysplasia in the first trimester. Four hundred and eighteen singleton pregnant women were recruited and the ratio of CCL to CRL was calculated according to gestational age. Fetuses with skeletal dysplasia were collected from database in the last 10 years. The CCL/CRL ratios were then calculated and the unpaired Student's t-test was to determine the significance of differences between normal fetuses and fetuses with skeletal dysplasia. Receiver operating characteristic curve was used to show the clinical sensitivity and specificity. In 418 normal fetuses, CCL increased linearly with gestation from a mean of 20 mm at 11 Increased fetal CCL/CRL ratio at 11-14 weeks' gestation is associated with an increased risk of skeletal dysplasia and may be useful in first-trimester screening for this condition.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2497-2504Informations de copyright
© 2022 American Institute of Ultrasound in Medicine.
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