Pharmacokinetic Drug Interaction Between Raloxifene and Cholecalciferol in Healthy Volunteers.

Adult Cholecalciferol / adverse effects Cross-Over Studies Drug Interactions Healthy Volunteers Humans Male Raloxifene Hydrochloride / adverse effects
cholecalciferol drug-drug interaction osteoporosis pharmacokinetics raloxifene

Journal

Clinical pharmacology in drug development
ISSN: 2160-7648
Titre abrégé: Clin Pharmacol Drug Dev
Pays: United States
ID NLM: 101572899

Informations de publication

Date de publication:
05 2022
Historique:
received: 12 08 2021
accepted: 07 12 2021
pubmed: 6 1 2022
medline: 30 4 2022
entrez: 5 1 2022
Statut: ppublish

Résumé

Osteoporosis is a common skeletal disorder, often leading to fragility fracture. Combination therapy with raloxifene, a selective estrogen receptor modulator, and cholecalciferol (vitamin D

Identifiants

DOI: 10.1002/cpdd.1062 PMID: 34984851 PMC: PMC9305550
pubmed: 34984851
doi: 10.1002/cpdd.1062
pmc: PMC9305550
doi:

Substances chimiques

Cholecalciferol 1C6V77QF41
Raloxifene Hydrochloride 4F86W47BR6

Banques de données

ClinicalTrials.gov
['NCT02654093']

Types de publication

Clinical Trial, Phase I Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

623-631

Informations de copyright

© 2022 The Authors. Clinical Pharmacology in Drug Development published by Wiley Periodicals LLC on behalf of American College of Clinical Pharmacology.

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Auteurs

Hae Won Lee (HW)

Department of Molecular Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Department of Clinical Pharmacology, Kyungpook National University Hospital, Daegu, Republic of Korea.

Woo Youl Kang (WY)

Department of Molecular Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Department of Clinical Pharmacology, Kyungpook National University Hospital, Daegu, Republic of Korea.

Wookjae Jung (W)

Department of Molecular Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Department of Clinical Pharmacology, Kyungpook National University Hospital, Daegu, Republic of Korea.

Mi-Ri Gwon (MR)

Department of Molecular Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Department of Clinical Pharmacology, Kyungpook National University Hospital, Daegu, Republic of Korea.

Kyunghee Cho (K)

Analytical Research Division, Biocore Co. Ltd., Seoul, Republic of Korea.

Backhwan Lee (B)

Department of Clinical Development, Alvogen Korea Co. Ltd., Seoul, Republic of Korea.

Sook Jin Seong (SJ)

Department of Molecular Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Department of Clinical Pharmacology, Kyungpook National University Hospital, Daegu, Republic of Korea.

Young-Ran Yoon (YR)

Department of Molecular Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Department of Clinical Pharmacology, Kyungpook National University Hospital, Daegu, Republic of Korea.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Pharmacokinetic Drug Interaction Between...
questionsmedicales.fr › Lipides › Lipides membranaires › Stérols › Cholécalciférol › Pharmacokinetic Drug Interaction Between...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Méthodologie en recherche épidémiologique › Études croisées › Pharmacokinetic Drug Interaction Between...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Interactions médicamenteuses › Pharmacokinetic Drug Interaction Between...
questionsmedicales.fr › Personnes › Bénévoles › Volontaires sains › Pharmacokinetic Drug Interaction Between...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Pharmacokinetic Drug Interaction Between...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures cycliques › Hydrocarbures aromatiques › Dérivés du benzène › Composés benzylidéniques › Stilbènes › Tamoxifène › Chlorhydrate de raloxifène › Pharmacokinetic Drug Interaction Between...