Immunoglobulin Profile and Lymphocyte Subsets in Preterm Neonates.
Journal
Indian pediatrics
ISSN: 0974-7559
Titre abrégé: Indian Pediatr
Pays: India
ID NLM: 2985062R
Informations de publication
Date de publication:
15 03 2022
15 03 2022
Historique:
pubmed:
8
1
2022
medline:
5
4
2022
entrez:
7
1
2022
Statut:
ppublish
Résumé
We documented the immunological profile of neonates and mothers, and lymphocyte subsets at birth. Consecutively born preterm neonates (26 to 31 weeks gestation) at our level III neonatal unit, fulfilling the inclusion criteria were enrolled. Immunoglobulin levels were assessed in maternal blood and in cord blood along with T cell subsets. A total of 115 neonates were enrolled. The mean cord levels for IgG, IgM and IgA, respectively were 5.34, 0.10 and 0.04 g/L and of B, T, NK and NK-T cells were 14%, 71%, 10% and 1%, respectively of total lymphocyte population. Cord IgG and IgA levels showed a significantly rising trend with increasing gestation (P=0.005 and 0.02, respectively) but not IgM and T cell subsets. Maternal immunoglobulins were similar in all gestations. The cord IgG and IgA increased with increasing gestation but not IgM in neonates.
Identifiants
pubmed: 34992185
pii: S097475591600389
pmc: PMC8964378
pii:
Substances chimiques
Immunoglobulin A
0
Immunoglobulin G
0
Immunoglobulin M
0
Immunoglobulins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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