The ALA5/ALA6/ALA7 repeat polymorphisms of the glutathione peroxidase-1 (GPx1) gene and autism spectrum disorder.

ASD GPx1 genetic screening GPx1 in vitro protein production GPx1 polymorphisms GPx1 protein activity autism spectrum disorder glutathione peroxidase 1

Journal

Autism research : official journal of the International Society for Autism Research
ISSN: 1939-3806
Titre abrégé: Autism Res
Pays: United States
ID NLM: 101461858

Informations de publication

Date de publication:
02 2022
Historique:
revised: 01 12 2021
received: 21 09 2021
accepted: 07 12 2021
pubmed: 9 1 2022
medline: 17 3 2022
entrez: 8 1 2022
Statut: ppublish

Résumé

Autism is a severe neurodevelopmental disorder leading to deficits in social interaction, communication, and several activities. An increasing number of evidence suggests a role of oxidative stress in the etiology of autism spectrum disorder (ASD). Indeed, impaired antioxidant mechanisms may lead to the inadequate removal of H

Identifiants

pubmed: 34997988
doi: 10.1002/aur.2655
pmc: PMC9304179
doi:

Substances chimiques

Glutathione Peroxidase EC 1.11.1.9
Glutathione Peroxidase GPX1 EC 1.11.1.9
GPX1 protein, human EC 1.11.1.9

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

215-221

Informations de copyright

© 2022 The Authors. Autism Research published by International Society for Autism Research and Wiley Periodicals LLC.

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Auteurs

Federica Carducci (F)

Dipartimento di Scienze Della Vita e Dell'Ambiente, Università Politecnica Delle Marche, Ancona, Italy.

Chiara Ardiccioni (C)

Dipartimento di Scienze Della Vita e Dell'Ambiente, Università Politecnica Delle Marche, Ancona, Italy.
New York-Marche Structural Biology Center (NY-MaSBiC), Università Politecnica Delle Marche, Ancona, Italy.

Rosamaria Fiorini (R)

Dipartimento di Scienze Della Vita e Dell'Ambiente, Università Politecnica Delle Marche, Ancona, Italy.

Arianna Vignini (A)

Dipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche, Università Politecnica Delle Marche, Ancona, Italy.

Alice Di Paolo (A)

Dipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche, Università Politecnica Delle Marche, Ancona, Italy.

Sonila Alia (S)

Dipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche, Università Politecnica Delle Marche, Ancona, Italy.

Marco Barucca (M)

Dipartimento di Scienze Della Vita e Dell'Ambiente, Università Politecnica Delle Marche, Ancona, Italy.

Maria Assunta Biscotti (MA)

Dipartimento di Scienze Della Vita e Dell'Ambiente, Università Politecnica Delle Marche, Ancona, Italy.

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Classifications MeSH