Long-term exposure to low ambient air pollution concentrations and mortality among 28 million people: results from seven large European cohorts within the ELAPSE project.

Adult Air Pollution / adverse effects Environmental Exposure / adverse effects Europe / epidemiology Humans Longitudinal Studies Mortality, Premature Multicenter Studies as Topic Particulate Matter / adverse effects

Journal

The Lancet. Planetary health
ISSN: 2542-5196
Titre abrégé: Lancet Planet Health
Pays: Netherlands
ID NLM: 101704339

Informations de publication

Date de publication:
01 2022
Historique:
received: 16 03 2021
revised: 13 09 2021
accepted: 20 09 2021
entrez: 9 1 2022
pubmed: 10 1 2022
medline: 22 3 2022
Statut: ppublish

Résumé

Long-term exposure to ambient air pollution has been associated with premature mortality, but associations at concentrations lower than current annual limit values are uncertain. We analysed associations between low-level air pollution and mortality within the multicentre study Effects of Low-Level Air Pollution: A Study in Europe (ELAPSE). In this multicentre longitudinal study, we analysed seven population-based cohorts of adults (age ≥30 years) within ELAPSE, from Belgium, Denmark, England, the Netherlands, Norway, Rome (Italy), and Switzerland (enrolled in 2000-11; follow-up until 2011-17). Mortality registries were used to extract the underlying cause of death for deceased individuals. Annual average concentrations of fine particulate matter (PM We analysed 28 153 138 participants contributing 257 859 621 person-years of observation, during which 3 593 741 deaths from non-accidental causes occurred. We found significant positive associations between non-accidental mortality and PM Long-term exposure to concentrations of PM Health Effects Institute.

Sections du résumé

BACKGROUND
Long-term exposure to ambient air pollution has been associated with premature mortality, but associations at concentrations lower than current annual limit values are uncertain. We analysed associations between low-level air pollution and mortality within the multicentre study Effects of Low-Level Air Pollution: A Study in Europe (ELAPSE).
METHODS
In this multicentre longitudinal study, we analysed seven population-based cohorts of adults (age ≥30 years) within ELAPSE, from Belgium, Denmark, England, the Netherlands, Norway, Rome (Italy), and Switzerland (enrolled in 2000-11; follow-up until 2011-17). Mortality registries were used to extract the underlying cause of death for deceased individuals. Annual average concentrations of fine particulate matter (PM
FINDINGS
We analysed 28 153 138 participants contributing 257 859 621 person-years of observation, during which 3 593 741 deaths from non-accidental causes occurred. We found significant positive associations between non-accidental mortality and PM
INTERPRETATION
Long-term exposure to concentrations of PM
FUNDING
Health Effects Institute.

Identifiants

DOI: 10.1016/S2542-5196(21)00277-1 PMID: 34998464
pubmed: 34998464
pii: S2542-5196(21)00277-1
doi: 10.1016/S2542-5196(21)00277-1
pii:
doi:

Substances chimiques

Particulate Matter 0

Types de publication

Journal Article Meta-Analysis Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e9-e18

Informations de copyright

Copyright © 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license. Published by Elsevier Ltd.. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests We declare no competing interests.

Auteurs

Massimo Stafoggia (M)

Department of Epidemiology, Lazio Region Health Service, ASL Roma 1, Rome, Italy; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. Electronic address: m.stafoggia@deplazio.it.

Bente Oftedal (B)

Department of Environmental Health, Norwegian Institute of Public Health, Oslo, Norway.

Jie Chen (J)

Institute for Risk Assessment Sciences, Utrecht University, Utrecht, Netherlands.

Sophia Rodopoulou (S)

Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

Matteo Renzi (M)

Department of Epidemiology, Lazio Region Health Service, ASL Roma 1, Rome, Italy.

Richard W Atkinson (RW)

Population Health Research Institute, St George's, University of London, London, UK.

Mariska Bauwelinck (M)

Interface Demography-Department of Sociology, Vrije Universiteit Brussel, Brussels, Belgium.

Jochem O Klompmaker (JO)

National Institute for Public Health and the Environment, Bilthoven, Netherlands; Harvard T H Chan School of Public Health, Boston, MA, USA.

Amar Mehta (A)

Section of Epidemiology, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.

Danielle Vienneau (D)

Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland.

Zorana J Andersen (ZJ)

Section of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.

Tom Bellander (T)

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; Centre for Occupational and Environmental Medicine, Region Stockholm, Stockholm, Sweden.

Jørgen Brandt (J)

Department of Environmental Science, Aarhus University, Roskilde, Denmark; iClimate Aarhus University Interdisciplinary Centre for Climate Change, Aarhus, Denmark.

Giulia Cesaroni (G)

Department of Epidemiology, Lazio Region Health Service, ASL Roma 1, Rome, Italy.

Kees de Hoogh (K)

Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland.

Daniela Fecht (D)

School of Public Health, Faculty of Medicine, Imperial College London, London, UK.

John Gulliver (J)

School of Public Health, Faculty of Medicine, Imperial College London, London, UK; Centre for Environmental Health and Sustainability and School of Geography, Geology and the Environment, University of Leicester, Leicester, UK.

Ole Hertel (O)

Department of Bioscience, Aarhus University, Roskilde, Denmark.

Barbara Hoffmann (B)

Institute for Occupational, Social and Environmental Medicine, Centre for Health and Society, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

Ulla A Hvidtfeldt (UA)

Danish Cancer Society Research Center, Copenhagen, Denmark.

Karl-Heinz Jöckel (KH)

Institute for Medical Informatics, Biometry and Epidemiology, Medical Faculty, University of Duisburg-Essen, Essen, Germany.

Jeanette T Jørgensen (JT)

Section of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.

Klea Katsouyanni (K)

Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece; School of Public Health, Faculty of Medicine, Imperial College London, London, UK.

Matthias Ketzel (M)

Department of Environmental Science, Aarhus University, Roskilde, Denmark; Global Centre for Clean Air Research, University of Surrey, Guildford, UK.

Doris Tove Kristoffersen (DT)

Norwegian Institute of Public Health, Cluster for Health Services Research, Oslo, Norway.

Anton Lager (A)

Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden.

Karin Leander (K)

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

Shuo Liu (S)

Section of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.

Petter L S Ljungman (PLS)

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; Department of Cardiology, Danderyd University Hospital, Stockholm, Sweden.

Gabriele Nagel (G)

Institute of Epidemiology and Medical Biometry, Ulm University, Ulm, Germany.

Göran Pershagen (G)

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; Centre for Occupational and Environmental Medicine, Region Stockholm, Stockholm, Sweden.

Annette Peters (A)

Institute of Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany; Ludwig Maximilians Universität München, Munich, Germany.

Ole Raaschou-Nielsen (O)

Department of Environmental Science, Aarhus University, Roskilde, Denmark; Danish Cancer Society Research Center, Copenhagen, Denmark.

Debora Rizzuto (D)

Department of Neurobiology, Care Sciences, and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden; Stockholm Gerontology Research Center, Stockholm, Sweden.

Sara Schramm (S)

Institute for Medical Informatics, Biometry and Epidemiology, University of Duisburg-Essen, University Hospital Essen, Germany.

Per E Schwarze (PE)

Division for Infection Control and Environmental Health, Norwegian Institute of Public Health, Oslo, Norway.

Gianluca Severi (G)

Exposome and Heredity Team, University Paris-Saclay, UVSQ, INSERM, Gustave Roussy, Villejuif, France; Department of Statistics, Computer Science and Applications "G Parenti", University of Florence, Italy.

Torben Sigsgaard (T)

Department of Public Health, Environment Occupation and Health, Danish Ramazzini Centre, Aarhus University, Aarhus, Denmark.

Maciek Strak (M)

Institute for Risk Assessment Sciences, Utrecht University, Utrecht, Netherlands; National Institute for Public Health and the Environment, Bilthoven, Netherlands.

Yvonne T van der Schouw (YT)

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.

Monique Verschuren (M)

National Institute for Public Health and the Environment, Bilthoven, Netherlands; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.

Gudrun Weinmayr (G)

Institute of Epidemiology and Medical Biometry, Ulm University, Ulm, Germany.

Kathrin Wolf (K)

Institute of Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany.

Emanuel Zitt (E)

Agency for Preventive and Social Medicine, Bregenz, Austria.

Evangelia Samoli (E)

Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

Francesco Forastiere (F)

Department of Epidemiology, Lazio Region Health Service, ASL Roma 1, Rome, Italy; School of Public Health, Faculty of Medicine, Imperial College London, London, UK.

Bert Brunekreef (B)

Institute for Risk Assessment Sciences, Utrecht University, Utrecht, Netherlands.

Gerard Hoek (G)

Institute for Risk Assessment Sciences, Utrecht University, Utrecht, Netherlands.

Nicole A H Janssen (NAH)

National Institute for Public Health and the Environment, Bilthoven, Netherlands.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Long-term exposure to low ambient air...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pollution de l'environnement › Pollution de l'air › Long-term exposure to low ambient air...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pollution de l'environnement › Exposition environnementale › Long-term exposure to low ambient air...
questionsmedicales.fr › Régions géographiques › Europe › Long-term exposure to low ambient air...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Long-term exposure to low ambient air...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études longitudinales › Long-term exposure to low ambient air...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Collecte de données › Registre civil › Mortalité › Mortalité prématurée › Long-term exposure to low ambient air...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études multicentriques comme sujet › Long-term exposure to low ambient air...
questionsmedicales.fr › Mélanges complexes › Matière particulaire › Long-term exposure to low ambient air...