Vitamin D Deficiency and Outcomes After Ankle Fusion: A Short Report.


Journal

Foot & ankle international
ISSN: 1944-7876
Titre abrégé: Foot Ankle Int
Pays: United States
ID NLM: 9433869

Informations de publication

Date de publication:
05 2022
Historique:
pubmed: 12 1 2022
medline: 10 5 2022
entrez: 11 1 2022
Statut: ppublish

Résumé

Vitamin D deficiency has been postulated as a cause for impaired bone healing and remodeling. The purpose of this study was to assess the potential association between low vitamin D levels and reoperation for nonunion following ankle fusion surgery. All adult patients (aged ≥18 years) who underwent ankle fusion procedures at a tertiary referral center from January 2010 to January 2019 with available vitamin D levels within 12 months preoperatively were retrospectively reviewed (n = 47). Patients were categorized as vitamin D deficient (<30 ng/mL) vs normal (31-80 ng/mL). The primary outcome was the incidence of reoperation secondary to nonunion. Secondary outcomes included incidence of reoperation not related to nonunion and the need for repeat reoperation. The average level in the vitamin D-deficient group (n = 17; 36.2%) was 16.9 vs 46.4 ng/mL in the normal group (n = 30; 63.8%). All recorded reoperations for nonunion occurred exclusively in the vitamin D-deficient cohort (4/17 [23.5%]; Vitamin D deficiency may be associated with an increased risk of reoperation for nonunion after ankle fusion.

Sections du résumé

BACKGROUND
Vitamin D deficiency has been postulated as a cause for impaired bone healing and remodeling. The purpose of this study was to assess the potential association between low vitamin D levels and reoperation for nonunion following ankle fusion surgery.
METHODS
All adult patients (aged ≥18 years) who underwent ankle fusion procedures at a tertiary referral center from January 2010 to January 2019 with available vitamin D levels within 12 months preoperatively were retrospectively reviewed (n = 47). Patients were categorized as vitamin D deficient (<30 ng/mL) vs normal (31-80 ng/mL). The primary outcome was the incidence of reoperation secondary to nonunion. Secondary outcomes included incidence of reoperation not related to nonunion and the need for repeat reoperation.
RESULTS
The average level in the vitamin D-deficient group (n = 17; 36.2%) was 16.9 vs 46.4 ng/mL in the normal group (n = 30; 63.8%). All recorded reoperations for nonunion occurred exclusively in the vitamin D-deficient cohort (4/17 [23.5%];
CONCLUSION
Vitamin D deficiency may be associated with an increased risk of reoperation for nonunion after ankle fusion.

Identifiants

pubmed: 35012371
doi: 10.1177/10711007211068785
doi:

Substances chimiques

Vitamin D 1406-16-2

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

703-705

Auteurs

Deepak Ramanathan (D)

Department of Orthopaedic Surgery, Cleveland Clinic Foundation, Cleveland, OH, USA.

Ahmed K Emara (AK)

Department of Orthopaedic Surgery, Cleveland Clinic Foundation, Cleveland, OH, USA.

Stephen Pinney (S)

Department of Orthopaedic Surgery, Cleveland Clinic Foundation, Cleveland, OH, USA.

Andrea Bell (A)

Department of Internal Medicine, MetroHealth hospital, Cleveland, OH, USA.

Sara Lyn Miniaci-Coxhead (SL)

Department of Orthopaedic Surgery, Cleveland Clinic Foundation, Cleveland, OH, USA.

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