Distribution of neurogranin-like immunoreactivity in the brain and sensory organs of the adult zebrafish.
Danio rerio
RC3
neurogranin
protein kinase C
teleost
zebrafish
Journal
The Journal of comparative neurology
ISSN: 1096-9861
Titre abrégé: J Comp Neurol
Pays: United States
ID NLM: 0406041
Informations de publication
Date de publication:
07 2022
07 2022
Historique:
revised:
30
12
2021
received:
30
07
2021
accepted:
03
01
2022
pubmed:
12
1
2022
medline:
24
5
2022
entrez:
11
1
2022
Statut:
ppublish
Résumé
We studied the expression of neurogranin in the brain and some sensory organs (barbel taste buds, olfactory organs, and retina) of adult zebrafish. Database analysis shows zebrafish has two paralog neurogranin genes (nrgna and nrgnb) that translate into three peptides with a conserved IQ domain, as in mammals. Western blots of zebrafish brain extracts using an anti-neurogranin antiserum revealed three separate bands, confirming the presence of three neurogranin peptides. Immunohistochemistry shows neurogranin-like expression in the brain and sensory organs (taste buds, neuromasts and olfactory epithelium), not being able to discern its three different peptides. In the retina, the most conspicuous positive cells were bipolar neurons. In the brain, immunopositive neurons were observed in all major regions (pallium, subpallium, preoptic area, hypothalamus, diencephalon, mesencephalon and rhombencephalon, including the cerebellum), a more extended distribution than in mammals. Interestingly, dendrites, cell bodies and axon terminals of some neurons were immunopositive, thus zebrafish neurogranins may play presynaptic and postsynaptic roles. Most positive neurons were found in primary sensory centers (viscerosensory column and medial octavolateral nucleus) and integrative centers (pallium, subpallium, optic tectum and cerebellum), which have complex synaptic circuitry. However, we also observed expression in areas not related to sensory or integrative functions, such as in cerebrospinal fluid-contacting cells associated with the hypothalamic recesses, which exhibited high neurogranin-like immunoreactivity. Together, these results reveal important differences with the patterns reported in mammals, suggesting divergent evolution from the common ancestor.
Identifiants
pubmed: 35015905
doi: 10.1002/cne.25297
pmc: PMC9415131
doi:
Substances chimiques
Neurogranin
132654-77-4
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1569-1587Subventions
Organisme : Predoctoral Fellowship from Xunta de Galicia
ID : ED481A-2019/003
Informations de copyright
© 2022 Wiley Periodicals LLC.
Références
Cold Spring Harb Perspect Biol. 2019 Feb 1;11(2):
pubmed: 29891560
J Comp Neurol. 2006 Nov 1;499(1):90-105
pubmed: 16958099
Neural Dev. 2006 Nov 29;1:4
pubmed: 17147780
Anal Biochem. 1999 Oct 15;274(2):278-82
pubmed: 10527526
J Comp Neurol. 1984 Sep 20;228(3):342-58
pubmed: 6480916
F1000Res. 2014 Dec 17;3:308
pubmed: 25713698
Brain Res. 2004 Jun 18;1011(2):206-20
pubmed: 15157807
J Biol Chem. 1999 Mar 19;274(12):7689-94
pubmed: 10075657
Chem Res Toxicol. 2020 Jan 21;33(1):95-118
pubmed: 31625720
J Comp Neurol. 2006 Jan 20;494(3):435-59
pubmed: 16320255
Anat Rec (Hoboken). 2013 Oct;296(10):1594-602
pubmed: 23956021
J Comp Neurol. 2004 Dec 6;480(2):180-203
pubmed: 15514934
J Comp Neurol. 2004 Jul 19;475(2):143-62
pubmed: 15211457
Eur J Neurosci. 2011 Jan;33(2):244-50
pubmed: 21198977
J Comp Neurol. 2010 Jul 1;518(13):2475-502
pubmed: 20503423
Cerebellum. 2006;5(4):268-74
pubmed: 17134989
PLoS One. 2012;7(3):e31658
pubmed: 22438865
Brain Behav Evol. 1995;46(4-5):275-318
pubmed: 8564468
J Comp Neurol. 2004 Nov 1;479(1):30-42
pubmed: 15389613
J Comp Neurol. 1974 Mar 1;154(1):43-60
pubmed: 4815183
Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11232-7
pubmed: 11016969
J Comp Neurol. 1978 Nov 1;182(1):89-122
pubmed: 81216
J Neurosci. 1990 Dec;10(12):3782-92
pubmed: 2269883
IUBMB Life. 2010 Aug;62(8):597-606
pubmed: 20665622
Biochem J. 2007 May 15;404(1):31-43
pubmed: 17295609
Mol Cell Neurosci. 2010 Apr;43(4):394-402
pubmed: 20123022
Integr Zool. 2009 Mar;4(1):53-63
pubmed: 20160963
Dev Dyn. 2002 Apr;223(4):483-96
pubmed: 11921337
J Biol Chem. 1994 Sep 2;269(35):22420-6
pubmed: 8071370
Brain Res. 2007 May 29;1149:87-100
pubmed: 17425949
Brain Res. 2004 Jun 18;1011(2):156-69
pubmed: 15157802
Front Neurosci. 2020 Jul 16;14:608
pubmed: 32765204
Annu Rev Neurosci. 2008;31:1-24
pubmed: 18275284
J Neurocytol. 2001 Jul;30(7):551-92
pubmed: 12118162
PLoS Comput Biol. 2020 Feb 12;16(2):e1006991
pubmed: 32049957
J Comp Neurol. 2018 Apr 15;526(6):1017-1040
pubmed: 29292495
J Comp Neurol. 1974 Mar 1;154(1):61-95
pubmed: 4815184
Front Neural Circuits. 2016 Apr 26;10:30
pubmed: 27199671
J Comp Neurol. 1993 Mar 8;329(2):188-200
pubmed: 8454729
Sci Rep. 2013;3:1392
pubmed: 23462742
Proc Natl Acad Sci U S A. 1992 Sep 15;89(18):8581-5
pubmed: 1528865
Histochem Cell Biol. 2019 Jun;151(6):521-530
pubmed: 30604284
FEBS Lett. 1993 Nov 29;335(1):109-13
pubmed: 8243654
Cerebellum. 2008;7(3):444-50
pubmed: 18633686
Dev Dyn. 2009 Jul;238(7):1836-50
pubmed: 19504456
Front Aging Neurosci. 2020 Oct 06;12:584743
pubmed: 33132903
Neurosci Lett. 1997 Jun 20;229(1):13-6
pubmed: 9224790
Nucleic Acids Res. 2001 Jul 15;29(14):2994-3005
pubmed: 11452024
Clin Biochem. 2015 Sep;48(13-14):843-8
pubmed: 26025774
J Comp Neurol. 2006 Feb 10;494(5):792-814
pubmed: 16374815
J Neurosci Res. 1990 Aug;26(4):397-408
pubmed: 2231781
J Neurocytol. 2001 Jul;30(7):593-654
pubmed: 12118163
J Comp Neurol. 2009 Oct 20;516(6):553-68
pubmed: 19673006
Arch Biochem Biophys. 1993 Sep;305(2):570-80
pubmed: 8080473
Prog Neurobiol. 1991;37(4):329-63
pubmed: 1758964
Curr Opin Cell Biol. 1991 Dec;3(6):988-91
pubmed: 1814370
J Comp Neurol. 2004 Dec 6;480(2):204-33
pubmed: 15514931
PLoS Genet. 2014 Sep 25;10(9):e1004615
pubmed: 25255244
FEBS Lett. 1991 Apr 22;282(1):183-8
pubmed: 2026258
Brain Res. 2014 Dec 3;1591:102-10
pubmed: 25446004
J Biol Chem. 1996 Jul 5;271(27):15911-7
pubmed: 8663125
FEBS Lett. 2003 Oct 9;553(1-2):90-4
pubmed: 14550552
J Comp Neurol. 2009 Sep 20;516(3):213-25
pubmed: 19598285
Dev Growth Differ. 2017 May;59(4):175-187
pubmed: 28470718
Neural Dev. 2012 Sep 18;7:32
pubmed: 22989074
Chem Senses. 2012 May;37(4):357-69
pubmed: 22167271
Neurosci Lett. 1996 Nov 29;219(3):183-6
pubmed: 8971810
Neurosci Lett. 2004 Jan 23;355(1-2):29-32
pubmed: 14729227
Brain Behav Evol. 2003;62(3):152-67
pubmed: 12966189
Mol Neurobiol. 2000 Aug-Dec;22(1-3):99-113
pubmed: 11414283
J Neurosci. 1991 Feb;11(2):311-7
pubmed: 1992002
Neuroscience. 1996 Jul;73(2):565-80
pubmed: 8783271
J Comp Neurol. 2011 Jul 1;519(10):1999-2022
pubmed: 21452220
Neuropharmacology. 2019 May 15;150:91-99
pubmed: 30902751
Front Neuroanat. 2013 May 09;7:9
pubmed: 23675325
J Comp Neurol. 2012 Nov 1;520(16):3786-802
pubmed: 22907678
Brain Behav Evol. 2007;69(2):96-104
pubmed: 17230017
J Comp Neurol. 2017 Feb 1;525(2):333-362
pubmed: 27343143
J Biol Chem. 1989 Jan 25;264(3):1824-8
pubmed: 2521487
Cell Rep. 2020 Sep 15;32(11):108143
pubmed: 32937118
J Neurosci Res. 2000 Mar 15;59(6):750-9
pubmed: 10700012
J Comp Neurol. 2011 Feb 15;519(3):576-98
pubmed: 21192085
PLoS Comput Biol. 2012;8(8):e1002618
pubmed: 22936893
J Comp Neurol. 1991 Aug 8;310(2):215-33
pubmed: 1955583
J Neurosci. 2015 May 13;35(19):7503-8
pubmed: 25972176
Cell Tissue Res. 2001 Sep;305(3):299-305
pubmed: 11572083
EMBO J. 2009 Oct 7;28(19):3027-39
pubmed: 19713936
Brain Res Mol Brain Res. 1995 Mar;29(1):119-30
pubmed: 7539519
Dev Neurobiol. 2009 Feb 1-15;69(2-3):124-40
pubmed: 19023859
J Comp Neurol. 2001 Nov 26;440(4):342-77
pubmed: 11745628
Mol Neurobiol. 1997 Oct;15(2):131-63
pubmed: 9396008
J Hirnforsch. 1989;30(3):339-47
pubmed: 2745970
Brain Behav Evol. 2000 Dec;56(6):330-9
pubmed: 11326138
J Comp Neurol. 2020 Dec 1;528(17):2888-2901
pubmed: 32003466
Prog Brain Res. 1967;25:1-93
pubmed: 4866554
J Comp Neurol. 2017 Jun 15;525(9):2265-2283
pubmed: 28295297
Front Neural Circuits. 2020 Mar 13;14:8
pubmed: 32231522
Neural Dev. 2013 Feb 21;8:3
pubmed: 23433260
Proc Natl Acad Sci U S A. 1993 Jul 1;90(13):6009-12
pubmed: 8327475
Front Mol Neurosci. 2020 Jan 24;12:322
pubmed: 32038160
Brain Behav Evol. 2009;73(4):229-52
pubmed: 19546532
J Biol Chem. 1991 Jan 5;266(1):229-37
pubmed: 1824695
Brain Behav Evol. 1996;47(3):113-37
pubmed: 8680846
Brain Res Dev Brain Res. 2002 Dec 15;139(2):255-65
pubmed: 12480140
Brain Res Bull. 2002 Feb-Mar 1;57(3-4):397-9
pubmed: 11922997
J Comp Neurol. 2004 Jun 21;474(2):209-26
pubmed: 15164423
J Comp Neurol. 2004 Sep 27;477(4):371-85
pubmed: 15329887
J Comp Neurol. 2005 Jul 4;487(3):300-11
pubmed: 15892096
J Comp Neurol. 2012 Feb 15;520(3):633-55
pubmed: 21858823
J Comp Neurol. 2011 Feb 1;519(2):247-76
pubmed: 21165974
Nat Neurosci. 2010 Nov;13(11):1354-6
pubmed: 20935642
J Comp Neurol. 2006 Jan 10;494(2):215-27
pubmed: 16320235
Neural Dev. 2008 Dec 16;3:36
pubmed: 19087349
Chem Senses. 1999 Feb;24(1):37-46
pubmed: 10192474
J Comp Neurol. 2022 Jun;530(8):1164-1194
pubmed: 34697803
J Comp Neurol. 2013 Feb 1;521(2):389-425
pubmed: 22736487
PLoS One. 2012;7(7):e41275
pubmed: 22848456
J Comp Neurol. 2022 Jul;530(10):1569-1587
pubmed: 35015905
J Comp Neurol. 2009 Dec 10;517(5):683-94
pubmed: 19827160
J Neurosci. 2004 Mar 3;24(9):2335-42
pubmed: 14999085
Dev Biol. 2009 Jun 15;330(2):406-26
pubmed: 19371731
J Biol Chem. 1995 Mar 24;270(12):6741-50
pubmed: 7896819
Brain Res Bull. 2008 Mar 18;75(2-4):191-205
pubmed: 18331871
J Comp Neurol. 2007 Jan 1;500(1):71-83
pubmed: 17099896
J Comp Neurol. 2009 Apr 20;513(6):685-701
pubmed: 19235874
Lab Anim. 2020 Jun;54(3):213-224
pubmed: 31510859
J Neurochem. 2003 Sep;86(6):1524-33
pubmed: 12950461
Br J Pharmacol. 2008 Aug;154(7):1400-13
pubmed: 18552866
J Comp Neurol. 1987 Feb 22;256(4):607-23
pubmed: 3558892