[Le LDL-cholestérol : une brique supplémentaire dans le mur de l'athérosclérose].
ATHEROSCLEROSIS and LDL-cholesterol : Another Brick In The Wall.
Journal
Annales de cardiologie et d'angeiologie
ISSN: 1768-3181
Titre abrégé: Ann Cardiol Angeiol (Paris)
Pays: France
ID NLM: 0142167
Informations de publication
Date de publication:
Apr 2022
Apr 2022
Historique:
received:
29
09
2021
accepted:
29
10
2021
pubmed:
19
1
2022
medline:
27
4
2022
entrez:
18
1
2022
Statut:
ppublish
Résumé
Atherosclerosis is one of the two major causes of mortality worldwide along with cancer and is responsible for myocardial infarction, stroke, and arteritis. Its pathophysiology is still partially understood which allows doubts referring to the preventive and curative treatments. Population screening for atherosclerosis remains marginal even though it should be the common practice. To encourage preventive screening and therapies, we propose a simple and easily understandable pathophysiology of atherosclerosis, explaining how the brick-wall of atheroma is build inside the intima of arteries using a metaphor: the LDL-cholesterol bricks, the oxidation cement, and the inflammatory mason.
Identifiants
pubmed: 35039145
pii: S0003-3928(21)00167-0
doi: 10.1016/j.ancard.2021.10.020
pii:
doi:
Substances chimiques
Cholesterol, LDL
0
Types de publication
Journal Article
Langues
fre
Sous-ensembles de citation
IM
Pagination
75-77Informations de copyright
Copyright © 2021 Elsevier Masson SAS. All rights reserved.
Déclaration de conflit d'intérêts
Conflict of interest 'The authors declare that there is no conflict of interest regarding this article.