Alain Tedgui

Affiliations

From the Université de Paris, Inserm U970, Paris Cardiovascular Research Center, Paris, France (H.A.-O., A.T.).

Publications (21)

Anticytokine Immune Therapy and Atherothrombotic Cardiovascular Risk.

Arteriosclerosis, thrombosis, and vascular biology

Avec: Hafid Ait-Oufella , Peter Libby , Alain Tedgui

MicroRNA-21 Deficiency Alters the Survival of Ly-6C

Arteriosclerosis, thrombosis, and vascular biology

Avec: Anna Chipont , Bruno Esposito , Inès Challier , Mélanie Montabord , Alain Tedgui , Ziad Mallat , Xavier Loyer , Stephane Potteaux

Harnessing intestinal tryptophan catabolism to relieve atherosclerosis in mice.

Nature communications

Avec: Mouna Chajadine , Ludivine Laurans , Tobias Radecke , Nirmala Mouttoulingam , Rida Al-Rifai , Emilie Bacquer , Clara Delaroque , Héloïse Rytter , Marius Bredon , Camille Knosp , José Vilar , Coralie Fontaine , Nadine Suffee , Marie Vandestienne , Bruno Esposito , Julien Dairou , Jean Marie Launay , Jacques Callebert , Alain Tedgui , Hafid Ait-Oufella , Harry Sokol , Benoit Chassaing , Soraya Taleb

TREM-1 orchestrates angiotensin II-induced monocyte trafficking and promotes experimental abdominal aortic aneurysm.

The Journal of clinical investigation

Avec: Marie Vandestienne , Yujiao Zhang , Icia Santos-Zas , Rida Al-Rifai , Jeremie Joffre , Andreas Giraud , Ludivine Laurans , Bruno Esposito , Florence Pinet , Patrick Bruneval , Juliette Raffort , Fabien Lareyre , Jose Vilar , Amir Boufenzer , Lea Guyonnet , Coralie Guerin , Eric Clauser , Jean-Sébastien Silvestre , Sylvie Lang , Laurie Soulat-Dufour , Alain Tedgui , Ziad Mallat , Soraya Taleb , Alexandre Boissonnas , Marc Derive , Giulia Chinetti , Hafid Ait-Oufella

Endothelial Cell Indoleamine 2, 3-Dioxygenase 1 Alters Cardiac Function After Myocardial Infarction Through Kynurenine.

Circulation

Avec: Nada Joe Melhem , Mouna Chajadine , Ingrid Gomez , Kiave-Yune Howangyin , Marion Bouvet , Camille Knosp , Yanyi Sun , Marie Rouanet , Ludivine Laurans , Olivier Cazorla , Mathilde Lemitre , José Vilar , Ziad Mallat , Alain Tedgui , Hafid Ait-Oufella , Jean-Sébastien Hulot , Jacques Callebert , Jean-Marie Launay , Jeremy Fauconnier , Jean-Sébastien Silvestre , Soraya Taleb

L-Wnk1 Deletion in Smooth Muscle Cells Causes Aortitis and Inflammatory Shift.

Circulation research

Avec: Helene Quelquejay , Rida Al-Rifai , Michele Silvestro , Marie Vandestienne , Irmine Ferreira , Tristan Mirault , Henrion Daniel , Xiaodan Zhong , Icia Santos-Zas , Guillaume Goudot , Paul Alayrac , Estelle Robidel , Gwennhael Autret , Daniel Balvay , Soraya Taleb , Alain Tedgui , Chantal M Boulanger , Alma Zernecke , Antoine-Emmanuel Saliba , Juliette Hadchouel , Bhama Ramkhelawon , Clement Cochain , Sonia Bergaya , Xavier Jeunemaitre , Hafid Ait-Oufella

Vascular consequences of inflammation: a position statement from the ESH Working Group on Vascular Structure and Function and the ARTERY Society.

Journal of hypertension

Avec: Luca Zanoli , Marie Briet , Jean P Empana , Pedro G Cunha , Kaisa M Mäki-Petäjä , Athanase D Protogerou , Alain Tedgui , Rhian M Touyz , Ernesto L Schiffrin , Bart Spronck , Philippe Bouchard , Charalambos Vlachopoulos , Rosa M Bruno , Pierre Boutouyrie , Auteur inconnu

Thymic stromal lymphopoietin is a key cytokine for the immunomodulation of atherogenesis with Freund's adjuvant.

Journal of cellular and molecular medicine

Avec: Martin Steinmetz , Ludivine Laurans , Sarah Nordsiek , Lena Weiß , Bieke van der Veken , Padmapriya Ponnuswamy , Bruno Esposito , Marie Vandestienne , Andreas Giraud , Cristina Göbbel , Eva Steffen , Tobias Radecke , Stephane Potteaux , Georg Nickenig , Tienush Rassaf , Alain Tedgui , Ziad Mallat

[Le LDL-cholestérol : une brique supplémentaire dans le mur de l'athérosclérose].

Annales de cardiologie et d'angeiologie

Avec: Adrien Pasteur-Rousseau , Alain Tedgui

Alternating high-fat diet enhances atherosclerosis by neutrophil reprogramming.

Nature

Avec: Jean-Rémi Lavillegrand , Rida Al-Rifai , Sara Thietart , Théo Guyon , Marie Vandestienne , Raphael Cohen , Vincent Duval , Xiaodan Zhong , Daniel Yen , Mumin Ozturk , Yutaka Negishi , Joanne Konkel , Emmanuel Pinteaux , Olivia Lenoir , Jose Vilar , Ludivine Laurans , Bruno Esposito , Marius Bredon , Harry Sokol , Marc Diedisheim , Antoine-Emmanuel Saliba , Alma Zernecke , Clément Cochain , Jessica Haub , Alain Tedgui , Nancy A Speck , Soraya Taleb , Musa M Mhlanga , Andreas Schlitzer , Niels P Riksen , Hafid Ait-Oufella

Regulatory T Cell-Enhancing Therapies to Treat Atherosclerosis.

Cells

Avec: Hafid Ait-Oufella , Jean-Rémi Lavillegrand , Alain Tedgui

Elevated plasma IL-6 and CRP levels are associated with adverse clinical outcomes and death in critically ill SARS-CoV-2 patients: inflammatory response of SARS-CoV-2 patients.

Annals of intensive care

Avec: Jean-Rémi Lavillegrand , Marc Garnier , Agathe Spaeth , Nathalie Mario , Geoffroy Hariri , Antoine Pilon , Enora Berti , Fabienne Fieux , Sara Thietart , Tomas Urbina , Matthieu Turpin , Lucie Darrivere , Muriel Fartoukh , Franck Verdonk , Guillaume Dumas , Alain Tedgui , Bertrand Guidet , Eric Maury , Yannick Chantran , Guillaume Voiriot , Hafid Ait-Oufella

JAK2V617F mutation drives vascular resident macrophages toward a pathogenic phenotype and promotes dissecting aortic aneurysm.

Nature communications

Avec: Rida Al-Rifai , Marie Vandestienne , Jean-Rémi Lavillegrand , Tristan Mirault , Julie Cornebise , Johanne Poisson , Ludivine Laurans , Bruno Esposito , Chloé James , Olivier Mansier , Pierre Hirsch , Fabrizia Favale , Rayan Braik , Camille Knosp , Jose Vilar , Giuseppe Rizzo , Alma Zernecke , Antoine-Emmanuel Saliba , Alain Tedgui , Maxime Lacroix , Lionel Arrive , Ziad Mallat , Soraya Taleb , Marc Diedisheim , Clément Cochain , Pierre-Emmanuel Rautou , Hafid Ait-Oufella

An obesogenic diet increases atherosclerosis through promoting microbiota dysbiosis-induced gut lymphocyte trafficking into the periphery.

Cell reports

Avec: Ludivine Laurans , Nirmala Mouttoulingam , Mouna Chajadine , Aonghus Lavelle , Marc Diedisheim , Emilie Bacquer , Laura Creusot , Nadine Suffee , Bruno Esposito , Nada Joe Melhem , Wilfried Le Goff , Yacine Haddad , Jean-Louis Paul , Dominique Rainteau , Alain Tedgui , Hafid Ait-Oufella , Laurence Zitvogel , Harry Sokol , Soraya Taleb

Regulatory T-Cell Response to Low-Dose Interleukin-2 in Ischemic Heart Disease.

NEJM evidence

Avec: Tian X Zhao , Rouchelle S Sriranjan , Zewen Kelvin Tuong , Yuning Lu , Andrew P Sage , Meritxell Nus , Annette Hubsch , Fotini Kaloyirou , Evangelia Vamvaka , Joanna Helmy , Michalis Kostapanos , Navazh Jalaludeen , David Klatzmann , Alain Tedgui , James H F Rudd , Sarah J Horton , Brian J P Huntly , Stephen P Hoole , Simon P Bond , Menna R Clatworthy , Joseph Cheriyan , Ziad Mallat

Cytotoxic CD8

Nature communications

Avec: Icia Santos-Zas , Jeremie Lemarié , Ivana Zlatanova , Marine Cachanado , Jean-Christophe Seghezzi , Hakim Benamer , Pascal Goube , Marie Vandestienne , Raphael Cohen , Maya Ezzo , Vincent Duval , Yujiao Zhang , Jin-Bo Su , Alain Bizé , Lucien Sambin , Philippe Bonnin , Maxime Branchereau , Christophe Heymes , Corinne Tanchot , José Vilar , Clement Delacroix , Jean-Sebastien Hulot , Clement Cochain , Patrick Bruneval , Nicolas Danchin , Alain Tedgui , Ziad Mallat , Tabassome Simon , Bijan Ghaleh , Jean-Sébastien Silvestre , Hafid Ait-Oufella

A defect in endothelial autophagy occurs in patients with non-alcoholic steatohepatitis and promotes inflammation and fibrosis.

Journal of hepatology

Avec: Adel Hammoutene , Louise Biquard , Juliette Lasselin , Marouane Kheloufi , Marion Tanguy , Anne-Clémence Vion , Jules Mérian , Nathalie Colnot , Xavier Loyer , Alain Tedgui , Patrice Codogno , Sophie Lotersztajn , Valérie Paradis , Chantal M Boulanger , Pierre-Emmanuel Rautou

Plasma and genetic determinants of soluble TREM-1 and major adverse cardiovascular events in a prospective cohort of acute myocardial infarction patients. Results from the FAST-MI 2010 study.

International journal of cardiology

Avec: Hafid Ait-Oufella , Mengyao Yu , Salma Kotti , Adrien Georges , Marie Vandestienne , Jeremie Joffre , François Roubille , Denis Angoulvant , Icia Santos-Zas , Alain Tedgui , Sébastien Gibot , Marc Derive , Nicolas Danchin , Nabila Bouatia-Naji , Tabassome Simon

Genetic inhibition of CARD9 accelerates the development of atherosclerosis in mice through CD36 dependent-defective autophagy.

Nature communications

Avec: Yujiao Zhang , Marie Vandestienne , Jean-Rémi Lavillegrand , Jeremie Joffre , Icia Santos-Zas , Aonghus Lavelle , Xiaodan Zhong , Wilfried Le Goff , Maryse Guérin , Rida Al-Rifai , Ludivine Laurans , Patrick Bruneval , Coralie Guérin , Marc Diedisheim , Melanie Migaud , Anne Puel , Fanny Lanternier , Jean-Laurent Casanova , Clément Cochain , Alma Zernecke , Antoine-Emmanuel Saliba , Michal Mokry , Jean-Sebastien Silvestre , Alain Tedgui , Ziad Mallat , Soraya Taleb , Olivia Lenoir , Cécile Vindis , Stéphane M Camus , Harry Sokol , Hafid Ait-Oufella

Mild dyslipidemia accelerates tumorigenesis through expansion of Ly6C

Nature communications

Avec: Thi Tran , Jean-Remi Lavillegrand , Cedric Lereverend , Bruno Esposito , Lucille Cartier , Melanie Montabord , Jaouen Tran-Rajau , Marc Diedisheim , Nadège Gruel , Khadija Ouguerram , Lea Paolini , Olivia Lenoir , Emmanuel Pinteaux , Eva Brabencova , Corinne Tanchot , Pauline Urquia , Jacqueline Lehmann-Che , Richard Le Naour , Yacine Merrouche , Christian Stockmann , Ziad Mallat , Alain Tedgui , Hafid Ait-Oufella , Eric Tartour , Stephane Potteaux

Early intermittent hyperlipidaemia alters tissue macrophages to fuel atherosclerosis.

Nature

Avec: Minoru Takaoka , Xiaohui Zhao , Hwee Ying Lim , Costan G Magnussen , Owen Ang , Nadine Suffee , Patricia R Schrank , Wei Siong Ong , Dimitrios Tsiantoulas , Felix Sommer , Sarajo K Mohanta , James Harrison , Yaxing Meng , Ludivine Laurans , Feitong Wu , Yuning Lu , Leanne Masters , Stephen A Newland , Laura Denti , Mingyang Hong , Mouna Chajadine , Markus Juonala , Juhani S Koskinen , Mika Kähönen , Katja Pahkala , Suvi P Rovio , Juha Mykkänen , Russell Thomson , Tsuneyasu Kaisho , Andreas J R Habenicht , Marc Clement , Alain Tedgui , Hafid Ait-Oufella , Tian X Zhao , Meritxell Nus , Christiana Ruhrberg , Soraya Taleb , Jesse W Williams , Olli T Raitakari , Véronique Angeli , Ziad Mallat

Réseau de co-auteurs

Hafid Ait-Oufella 15 collaborations

Ziad Mallat 10 collaborations

Ludivine Laurans 9 collaborations

Marie Vandestienne 9 collaborations

Soraya Taleb 9 collaborations

Bruno Esposito 8 collaborations

Rida Al-Rifai 6 collaborations

Icia Santos-Zas 5 collaborations

Jean-Rémi Lavillegrand 5 collaborations

Marc Diedisheim 5 collaborations

Mouna Chajadine 4 collaborations

Harry Sokol 4 collaborations

Alma Zernecke 4 collaborations

Antoine-Emmanuel Saliba 4 collaborations

Stephane Potteaux 3 collaborations

Camille Knosp 3 collaborations

José Vilar 3 collaborations

Nadine Suffee 3 collaborations

Yujiao Zhang 3 collaborations

Jeremie Joffre 3 collaborations

Patrick Bruneval 3 collaborations

Jose Vilar 3 collaborations

Jean-Sébastien Silvestre 3 collaborations

Xiaodan Zhong 3 collaborations

Olivia Lenoir 3 collaborations

Clément Cochain 3 collaborations

Xavier Loyer 2 collaborations

Tobias Radecke 2 collaborations

Nirmala Mouttoulingam 2 collaborations

Emilie Bacquer 2 collaborations

Marius Bredon 2 collaborations

Jacques Callebert 2 collaborations

Andreas Giraud 2 collaborations

Marc Derive 2 collaborations

Nada Joe Melhem 2 collaborations

Tristan Mirault 2 collaborations

Chantal M Boulanger 2 collaborations

Clement Cochain 2 collaborations

Sara Thietart 2 collaborations

Raphael Cohen 2 collaborations

Vincent Duval 2 collaborations

Emmanuel Pinteaux 2 collaborations

Pierre-Emmanuel Rautou 2 collaborations

Aonghus Lavelle 2 collaborations

Wilfried Le Goff 2 collaborations

Tian X Zhao 2 collaborations

Yuning Lu 2 collaborations

Meritxell Nus 2 collaborations

Corinne Tanchot 2 collaborations

Nicolas Danchin 2 collaborations

Tabassome Simon 2 collaborations

Peter Libby 1 collaboration

Anna Chipont 1 collaboration

Inès Challier 1 collaboration

Mélanie Montabord 1 collaboration

Clara Delaroque 1 collaboration

Héloïse Rytter 1 collaboration

Coralie Fontaine 1 collaboration

Julien Dairou 1 collaboration

Jean Marie Launay 1 collaboration

Benoit Chassaing 1 collaboration

Florence Pinet 1 collaboration

Juliette Raffort 1 collaboration

Fabien Lareyre 1 collaboration

Amir Boufenzer 1 collaboration

Lea Guyonnet 1 collaboration

Coralie Guerin 1 collaboration

Eric Clauser 1 collaboration

Sylvie Lang 1 collaboration

Laurie Soulat-Dufour 1 collaboration

Alexandre Boissonnas 1 collaboration

Giulia Chinetti 1 collaboration

Ingrid Gomez 1 collaboration

Kiave-Yune Howangyin 1 collaboration

Marion Bouvet 1 collaboration

Yanyi Sun 1 collaboration

Marie Rouanet 1 collaboration

Olivier Cazorla 1 collaboration

Mathilde Lemitre 1 collaboration

Jean-Sébastien Hulot 1 collaboration

Jean-Marie Launay 1 collaboration

Jeremy Fauconnier 1 collaboration

Helene Quelquejay 1 collaboration

Michele Silvestro 1 collaboration

Irmine Ferreira 1 collaboration

Henrion Daniel 1 collaboration

Guillaume Goudot 1 collaboration

Paul Alayrac 1 collaboration

Estelle Robidel 1 collaboration

Gwennhael Autret 1 collaboration

Daniel Balvay 1 collaboration

Juliette Hadchouel 1 collaboration

Bhama Ramkhelawon 1 collaboration

Sonia Bergaya 1 collaboration

Xavier Jeunemaitre 1 collaboration

Luca Zanoli 1 collaboration

Marie Briet 1 collaboration

Jean P Empana 1 collaboration

Pedro G Cunha 1 collaboration

Kaisa M Mäki-Petäjä 1 collaboration

Athanase D Protogerou 1 collaboration

Rhian M Touyz 1 collaboration

Ernesto L Schiffrin 1 collaboration

Bart Spronck 1 collaboration

Philippe Bouchard 1 collaboration

Charalambos Vlachopoulos 1 collaboration

Rosa M Bruno 1 collaboration

Pierre Boutouyrie 1 collaboration

None None 1 collaboration

Martin Steinmetz 1 collaboration

Sarah Nordsiek 1 collaboration

Lena Weiß 1 collaboration

Bieke van der Veken 1 collaboration

Padmapriya Ponnuswamy 1 collaboration

Cristina Göbbel 1 collaboration

Eva Steffen 1 collaboration

Georg Nickenig 1 collaboration

Tienush Rassaf 1 collaboration

Adrien Pasteur-Rousseau 1 collaboration

Théo Guyon 1 collaboration

Daniel Yen 1 collaboration

Mumin Ozturk 1 collaboration

Yutaka Negishi 1 collaboration

Joanne Konkel 1 collaboration

Jessica Haub 1 collaboration

Nancy A Speck 1 collaboration

Musa M Mhlanga 1 collaboration

Andreas Schlitzer 1 collaboration

Niels P Riksen 1 collaboration

Marc Garnier 1 collaboration

Agathe Spaeth 1 collaboration

Nathalie Mario 1 collaboration

Geoffroy Hariri 1 collaboration

Antoine Pilon 1 collaboration

Enora Berti 1 collaboration

Fabienne Fieux 1 collaboration

Tomas Urbina 1 collaboration

Matthieu Turpin 1 collaboration

Lucie Darrivere 1 collaboration

Muriel Fartoukh 1 collaboration

Franck Verdonk 1 collaboration

Guillaume Dumas 1 collaboration

Bertrand Guidet 1 collaboration

Eric Maury 1 collaboration

Yannick Chantran 1 collaboration

Guillaume Voiriot 1 collaboration

Julie Cornebise 1 collaboration

Johanne Poisson 1 collaboration

Chloé James 1 collaboration

Olivier Mansier 1 collaboration

Pierre Hirsch 1 collaboration

Fabrizia Favale 1 collaboration

Rayan Braik 1 collaboration

Giuseppe Rizzo 1 collaboration

Maxime Lacroix 1 collaboration

Lionel Arrive 1 collaboration

Laura Creusot 1 collaboration

Yacine Haddad 1 collaboration

Jean-Louis Paul 1 collaboration

Dominique Rainteau 1 collaboration

Laurence Zitvogel 1 collaboration

Rouchelle S Sriranjan 1 collaboration

Zewen Kelvin Tuong 1 collaboration

Andrew P Sage 1 collaboration

Annette Hubsch 1 collaboration

Fotini Kaloyirou 1 collaboration

Evangelia Vamvaka 1 collaboration

Joanna Helmy 1 collaboration

Michalis Kostapanos 1 collaboration

Navazh Jalaludeen 1 collaboration

David Klatzmann 1 collaboration

James H F Rudd 1 collaboration

Sarah J Horton 1 collaboration

Brian J P Huntly 1 collaboration

Stephen P Hoole 1 collaboration

Simon P Bond 1 collaboration

Menna R Clatworthy 1 collaboration

Joseph Cheriyan 1 collaboration

Jeremie Lemarié 1 collaboration

Ivana Zlatanova 1 collaboration

Marine Cachanado 1 collaboration

Jean-Christophe Seghezzi 1 collaboration

Hakim Benamer 1 collaboration

Pascal Goube 1 collaboration

Maya Ezzo 1 collaboration

Jin-Bo Su 1 collaboration

Alain Bizé 1 collaboration

Lucien Sambin 1 collaboration

Philippe Bonnin 1 collaboration

Maxime Branchereau 1 collaboration

Christophe Heymes 1 collaboration

Clement Delacroix 1 collaboration

Jean-Sebastien Hulot 1 collaboration

Bijan Ghaleh 1 collaboration

Adel Hammoutene 1 collaboration

Louise Biquard 1 collaboration

Juliette Lasselin 1 collaboration

Marouane Kheloufi 1 collaboration

Marion Tanguy 1 collaboration

Anne-Clémence Vion 1 collaboration

Jules Mérian 1 collaboration

Nathalie Colnot 1 collaboration

Patrice Codogno 1 collaboration

Sophie Lotersztajn 1 collaboration

Valérie Paradis 1 collaboration

Mengyao Yu 1 collaboration

Salma Kotti 1 collaboration

Adrien Georges 1 collaboration

François Roubille 1 collaboration

Denis Angoulvant 1 collaboration

Sébastien Gibot 1 collaboration

Nabila Bouatia-Naji 1 collaboration

Maryse Guérin 1 collaboration

Coralie Guérin 1 collaboration

Melanie Migaud 1 collaboration

Anne Puel 1 collaboration

Fanny Lanternier 1 collaboration

Jean-Laurent Casanova 1 collaboration

Michal Mokry 1 collaboration

Jean-Sebastien Silvestre 1 collaboration

Cécile Vindis 1 collaboration

Stéphane M Camus 1 collaboration

Thi Tran 1 collaboration

Jean-Remi Lavillegrand 1 collaboration

Cedric Lereverend 1 collaboration

Lucille Cartier 1 collaboration

Melanie Montabord 1 collaboration

Jaouen Tran-Rajau 1 collaboration

Nadège Gruel 1 collaboration

Khadija Ouguerram 1 collaboration

Lea Paolini 1 collaboration

Eva Brabencova 1 collaboration

Pauline Urquia 1 collaboration

Jacqueline Lehmann-Che 1 collaboration

Richard Le Naour 1 collaboration

Yacine Merrouche 1 collaboration

Christian Stockmann 1 collaboration

Eric Tartour 1 collaboration

Minoru Takaoka 1 collaboration

Xiaohui Zhao 1 collaboration

Hwee Ying Lim 1 collaboration

Costan G Magnussen 1 collaboration

Owen Ang 1 collaboration

Patricia R Schrank 1 collaboration

Wei Siong Ong 1 collaboration

Dimitrios Tsiantoulas 1 collaboration

Felix Sommer 1 collaboration

Sarajo K Mohanta 1 collaboration

James Harrison 1 collaboration

Yaxing Meng 1 collaboration

Feitong Wu 1 collaboration

Leanne Masters 1 collaboration

Stephen A Newland 1 collaboration

Laura Denti 1 collaboration

Mingyang Hong 1 collaboration

Markus Juonala 1 collaboration

Juhani S Koskinen 1 collaboration

Mika Kähönen 1 collaboration

Katja Pahkala 1 collaboration

Suvi P Rovio 1 collaboration

Juha Mykkänen 1 collaboration

Russell Thomson 1 collaboration

Tsuneyasu Kaisho 1 collaboration

Andreas J R Habenicht 1 collaboration

Marc Clement 1 collaboration

Christiana Ruhrberg 1 collaboration

Jesse W Williams 1 collaboration

Olli T Raitakari 1 collaboration

Véronique Angeli 1 collaboration