The imprinted
chromosomes
development
developmental biology
gene expression
genomic imprinting
growth
hypothalamus
mouse
Journal
eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614
Informations de publication
Date de publication:
20 01 2022
20 01 2022
Historique:
received:
10
12
2020
accepted:
19
01
2022
pubmed:
21
1
2022
medline:
16
3
2022
entrez:
20
1
2022
Statut:
epublish
Résumé
Genomic imprinting refers to the mono-allelic and parent-specific expression of a subset of genes. While long recognized for their role in embryonic development, imprinted genes have recently emerged as important modulators of postnatal physiology, notably through hypothalamus-driven functions. Here, using mouse models of loss, gain and parental inversion of expression, we report that the paternally expressed
Identifiants
pubmed: 35049495
doi: 10.7554/eLife.65641
pii: 65641
pmc: PMC8809892
doi:
pii:
Substances chimiques
DNA-Binding Proteins
0
Zdbf2 protein, mouse
0
Banques de données
GEO
['GSE153265']
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2022, Glaser et al.
Déclaration de conflit d'intérêts
JG, JI, MB, MM, AG, CJ, AT, CG No competing interests declared, DB Reviewing editor, eLife
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