A Vaccine Based on the A/ASIA/G-VII Lineage of Foot-and-Mouth Disease Virus Offers Low Levels of Protection against Circulating Viruses from the A/ASIA/Iran-05 lineage.
Animals
Antibodies, Neutralizing
/ blood
Antibodies, Viral
/ blood
Antigens, Viral
/ immunology
Cattle
Cattle Diseases
/ immunology
Cross Protection
Foot-and-Mouth Disease
/ immunology
Foot-and-Mouth Disease Virus
/ genetics
Immunity, Heterologous
RNA, Viral
/ analysis
Serogroup
Vaccine Potency
Viral Vaccines
/ immunology
Viremia
/ prevention & control
Virus Shedding
A/ASIA/Iran-05 lineage variant
cattle
foot-and-mouth disease virus
heterologous challenge
serotype A/ASIA/G-VII lineage vaccine
vaccine efficacy
Journal
Viruses
ISSN: 1999-4915
Titre abrégé: Viruses
Pays: Switzerland
ID NLM: 101509722
Informations de publication
Date de publication:
06 01 2022
06 01 2022
Historique:
received:
27
10
2021
revised:
14
12
2021
accepted:
27
12
2021
entrez:
22
1
2022
pubmed:
23
1
2022
medline:
22
2
2022
Statut:
epublish
Résumé
The recent emergence and circulation of the A/ASIA/G-VII (A/G-VII) lineage of foot-and-mouth disease virus (FMDV) in the Middle East has resulted in the development of homologous vaccines to ensure susceptible animals are sufficiently protected against clinical disease. However, a second serotype A lineage called A/ASIA/Iran-05 (A/IRN/05) continues to circulate in the region and it is therefore imperative to ensure vaccine strains used will protect against both lineages. In addition, for FMDV vaccine banks that usually hold a limited number of strains, it is necessary to include strains with a broad antigenic coverage. To assess the cross protective ability of an A/G-VII emergency vaccine (formulated at 43 (95% CI 8-230) PD
Identifiants
pubmed: 35062300
pii: v14010097
doi: 10.3390/v14010097
pmc: PMC8781018
pii:
doi:
Substances chimiques
Antibodies, Neutralizing
0
Antibodies, Viral
0
Antigens, Viral
0
RNA, Viral
0
Viral Vaccines
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Biotechnology and Biological Sciences Research Council
ID : BBS/E/I/00007036
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BBS/E/I/0007035
Pays : United Kingdom
Références
Virus Res. 2003 Jan;91(1):65-80
pubmed: 12527438
Virology. 1957 Oct;4(2):224-36
pubmed: 13496542
Expert Rev Vaccines. 2018 Jul;17(7):577-591
pubmed: 29950121
Vet Microbiol. 2004 Jan 14;98(1):29-36
pubmed: 14738779
Mol Biol Evol. 2021 Sep 27;38(10):4346-4361
pubmed: 34115138
Vet Res. 2015 Apr 17;46:43
pubmed: 25928658
Virus Evol. 2021 Mar 19;7(1):veab009
pubmed: 35186323
Transbound Emerg Dis. 2015 Jun;62(3):328-31
pubmed: 23734722
Epidemiol Infect. 2015 Aug;143(11):2279-86
pubmed: 25464822
Am J Vet Res. 1970 Jul;31(7):1187-96
pubmed: 4194347
Genome Announc. 2016 Jan 21;4(1):
pubmed: 26798100
Emerg Infect Dis. 2018 Jun;24(6):1073-1078
pubmed: 29774839
Vaccine. 2018 Mar 27;36(14):1901-1907
pubmed: 29506922
Philos Trans R Soc Lond B Biol Sci. 2009 Sep 27;364(1530):2657-67
pubmed: 19687036
mBio. 2020 Aug 4;11(4):
pubmed: 32753488
ALTEX. 2018 Jul 12;35(4):489-494
pubmed: 30015984
Res Vet Sci. 1976 Mar;20(2):142-7
pubmed: 178035
J Virol Methods. 2003 Oct;113(1):35-41
pubmed: 14500125
Virus Res. 2005 Sep;112(1-2):52-9
pubmed: 16022900
Clin Microbiol Rev. 2004 Apr;17(2):465-93
pubmed: 15084510