Intrahepatic Injection of Sodium Pentobarbital as an Alternative to Intraperitoneal Injection for the Euthanasia of Rats (
Journal
Journal of the American Association for Laboratory Animal Science : JAALAS
ISSN: 2769-6677
Titre abrégé: J Am Assoc Lab Anim Sci
Pays: United States
ID NLM: 101269489
Informations de publication
Date de publication:
01 03 2022
01 03 2022
Historique:
pubmed:
23
1
2022
medline:
5
4
2022
entrez:
22
1
2022
Statut:
ppublish
Résumé
The most commonly accepted method of rat euthanasia in North America is intraperitoneal injection of sodium pentobarbital (PB). However, misinjection can occur, and intraperitoneal PB may cause pain and distress. The objective of this study was to test an alternative method of euthanasia: intrahepatic injection of PB. A pilot study was conducted to develop a method of intrahepatic injections (evaluated using CT scans and test injections), followed by a full study comparing intraperitoneal (
Identifiants
pubmed: 35063046
doi: 10.30802/AALAS-JAALAS-21-000094
pmc: PMC8956212
doi:
Substances chimiques
Sodium
9NEZ333N27
Pentobarbital
I4744080IR
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
201-207Références
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