The role of the electrocardiogram in the recognition of cardiac transplant rejection: A systematic review and meta-analysis.
ECG
cardio transplant rejection
heart transplant rejection
rejection diagnosis
Journal
Clinical cardiology
ISSN: 1932-8737
Titre abrégé: Clin Cardiol
Pays: United States
ID NLM: 7903272
Informations de publication
Date de publication:
Mar 2022
Mar 2022
Historique:
received:
10
12
2021
accepted:
04
01
2022
pubmed:
24
1
2022
medline:
17
3
2022
entrez:
23
1
2022
Statut:
ppublish
Résumé
In cardiac transplant recipients, the electrocardiogram (ECG) is a noninvasive measure of early allograft rejection. The ECG can predict an acute cellular rejection, thus shortening the time to recognition of rejection. Earlier diagnosis has the potential to reduce the number and severity of rejection episodes. A systematic literature review was conducted to identify and select the original research reports on using electrocardiography in diagnosing cardiac transplant rejection in accordance with the PRISMA guidelines. Studies included reported sensitivity and specificity of ECG readings in heart transplant recipients during the first post-transplant year. Data were analyzed with Review manager version 5.4. p-value was used in testing the significant difference. After the removal of duplicates, 98 articles were eligible for screening. After the full-text screening, a total of 17 papers were included in the review based on the above criteria. A meta-analysis of five studies was done. In heart transplant recipients, a noninvasive measure of early allograft rejection has the potential to reduce the number and severity of rejection episodes by reducing the time and cost of surveillance of rejection and shortening the time to recognition of rejection.
Sections du résumé
BACKGROUND
BACKGROUND
In cardiac transplant recipients, the electrocardiogram (ECG) is a noninvasive measure of early allograft rejection. The ECG can predict an acute cellular rejection, thus shortening the time to recognition of rejection. Earlier diagnosis has the potential to reduce the number and severity of rejection episodes.
METHODOLOGY
METHODS
A systematic literature review was conducted to identify and select the original research reports on using electrocardiography in diagnosing cardiac transplant rejection in accordance with the PRISMA guidelines. Studies included reported sensitivity and specificity of ECG readings in heart transplant recipients during the first post-transplant year. Data were analyzed with Review manager version 5.4. p-value was used in testing the significant difference.
RESULTS
RESULTS
After the removal of duplicates, 98 articles were eligible for screening. After the full-text screening, a total of 17 papers were included in the review based on the above criteria. A meta-analysis of five studies was done.
CONCLUSION
CONCLUSIONS
In heart transplant recipients, a noninvasive measure of early allograft rejection has the potential to reduce the number and severity of rejection episodes by reducing the time and cost of surveillance of rejection and shortening the time to recognition of rejection.
Identifiants
pubmed: 35066923
doi: 10.1002/clc.23783
pmc: PMC8922543
doi:
Types de publication
Journal Article
Meta-Analysis
Review
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
258-264Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2022 The Authors. Clinical Cardiology published by Wiley Periodicals LLC.
Références
J Heart Lung Transplant. 1999 Jun;18(6):499-509
pubmed: 10395347
Med Klin (Munich). 2006 Feb 15;101(2):99-106
pubmed: 16501906
Transpl Int. 1989 Oct;2(3):143-6
pubmed: 2803486
Transplantation. 1992 Jan;53(1):124-7
pubmed: 1733059
Clin Cardiol. 2022 Mar;45(3):258-264
pubmed: 35066923
J Heart Lung Transplant. 2011 Oct;30(10):1104-22
pubmed: 21962018
Circulation. 1990 Jan;81(1):72-7
pubmed: 2297850
Eur J Cardiothorac Surg. 1993;7(9):489-94; discussion 488
pubmed: 8217228
Ann Noninvasive Electrocardiol. 2005 Jan;10(1):60-4
pubmed: 15649239
J Cardiol Cases. 2012 Feb 28;5(2):e113-e117
pubmed: 30532917
Pacing Clin Electrophysiol. 1991 Jun;14(6):1024-31
pubmed: 1715063
Am Heart J. 1996 Oct;132(4):820-6
pubmed: 8831372
Circulation. 1984 Sep;70(3 Pt 2):I124-9
pubmed: 6378424
Am J Crit Care. 2018 Mar;27(2):145-150
pubmed: 29496772
Circulation. 1987 Jul;76(1):101-8
pubmed: 3297388
BMC Cardiovasc Disord. 2012 Mar 02;12:14
pubmed: 22386040
J Am Soc Echocardiogr. 2006 Oct;19(10):1295-300
pubmed: 17000376
IEEE Trans Biomed Eng. 2017 May;64(5):1149-1156
pubmed: 27448338
Heart. 1999 Aug;82(2):241-3
pubmed: 10409545
Yonsei Med J. 2019 May;60(5):423-428
pubmed: 31016903
J Heart Lung Transplant. 2017 Dec;36(12):1311-1318
pubmed: 29173394
BMJ. 2009 Jul 21;339:b2535
pubmed: 19622551
J Cardiovasc Electrophysiol. 1994 Dec;5(12):1053-63
pubmed: 7697207
J Am Coll Cardiol. 1992 Mar 1;19(3):553-8
pubmed: 1538009