Efficacy of five 'sporicidal' surface disinfectants against Clostridioides difficile spores in suspension tests and 4-field tests.
4-field test
C. difficile
Glutaraldehyde
Peracetic acid
Sporicidal activity
Suspension test
Journal
The Journal of hospital infection
ISSN: 1532-2939
Titre abrégé: J Hosp Infect
Pays: England
ID NLM: 8007166
Informations de publication
Date de publication:
Apr 2022
Apr 2022
Historique:
received:
31
08
2021
revised:
03
01
2022
accepted:
13
01
2022
pubmed:
26
1
2022
medline:
1
4
2022
entrez:
25
1
2022
Statut:
ppublish
Résumé
A sporicidal surface disinfection is recommended both for the outbreak and the endemic setting but a comparative evaluation on the efficacy of 'sporicidal' surface disinfectants using suspension tests and 4-field tests has not been performed. To determine the efficacy of five 'sporicidal' surface disinfectants (three ready-to-use wipes (A, B, E), two concentrates (C, D) based on peroxides or aldehydes against C. difficile spores. The efficacy was determined under clean conditions using a suspension test and the 4-field test. Each test was performed in duplicate in two separate laboratories. Wipes were wrung to collect the solution for the suspension tests. Product A (peracetic acid; 5 min), product C (peracetic acid; 2% solution in 15 min or 1% solution in 30 min) and product D (peracetic acid; only 2% solution in 15 min) were effective with at least a 4 log Not all surface disinfectants with a sporicidal claim were effective against C. difficile spores in standardized suspension tests and in the 4-field test. In clinical practice preference should be given to products that reliably pass the efficacy criteria of both types of tests.
Sections du résumé
BACKGROUND
BACKGROUND
A sporicidal surface disinfection is recommended both for the outbreak and the endemic setting but a comparative evaluation on the efficacy of 'sporicidal' surface disinfectants using suspension tests and 4-field tests has not been performed.
AIM
OBJECTIVE
To determine the efficacy of five 'sporicidal' surface disinfectants (three ready-to-use wipes (A, B, E), two concentrates (C, D) based on peroxides or aldehydes against C. difficile spores.
METHODS
METHODS
The efficacy was determined under clean conditions using a suspension test and the 4-field test. Each test was performed in duplicate in two separate laboratories. Wipes were wrung to collect the solution for the suspension tests.
RESULTS
RESULTS
Product A (peracetic acid; 5 min), product C (peracetic acid; 2% solution in 15 min or 1% solution in 30 min) and product D (peracetic acid; only 2% solution in 15 min) were effective with at least a 4 log
CONCLUSIONS
CONCLUSIONS
Not all surface disinfectants with a sporicidal claim were effective against C. difficile spores in standardized suspension tests and in the 4-field test. In clinical practice preference should be given to products that reliably pass the efficacy criteria of both types of tests.
Identifiants
pubmed: 35077809
pii: S0195-6701(22)00025-1
doi: 10.1016/j.jhin.2022.01.010
pii:
doi:
Substances chimiques
Disinfectants
0
Peracetic Acid
I6KPI2E1HD
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
140-147Informations de copyright
Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.