Phylogenomics of Severe Acute Respiratory Syndrome Coronavirus 2 in Emergency Shelters for People Experiencing Homelessness.

COVID-19 / epidemiology Emergency Shelter Ill-Housed Persons Humans Phylogeny SARS-CoV-2 / genetics
SARS-CoV-2 genome homeless shelters transmission

Journal

The Journal of infectious diseases
ISSN: 1537-6613
Titre abrégé: J Infect Dis
Pays: United States
ID NLM: 0413675

Informations de publication

Date de publication:
24 08 2022
Historique:
received: 29 09 2021
accepted: 25 01 2022
pubmed: 30 1 2022
medline: 27 8 2022
entrez: 29 1 2022
Statut: ppublish

Résumé

Residents and staff of emergency shelters for people experiencing homelessness (PEH) are at high risk of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The importance of shelter-related transmission of SARS-CoV-2 in this population remains unclear. It is also unknown whether there is significant spread of shelter-related viruses into surrounding communities. We analyzed genome sequence data for 28 SARS-CoV-2-positive specimens collected from 8 shelters in King County, Washington between March and October, 2020. We identified at least 12 separate SARS-CoV-2 introduction events into these 8 shelters and estimated that 57% (16 of 28) of the examined cases of SARS-CoV-2 infection were the result of intrashelter transmission. However, we identified just a few SARS-CoV-2 specimens from Washington that were possible descendants of shelter viruses. Our data suggest that SARS-CoV-2 spread in shelters is common, but we did not observe evidence of widespread transmission of shelter-related viruses into the general population.

Sections du résumé

BACKGROUND
Residents and staff of emergency shelters for people experiencing homelessness (PEH) are at high risk of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The importance of shelter-related transmission of SARS-CoV-2 in this population remains unclear. It is also unknown whether there is significant spread of shelter-related viruses into surrounding communities.
METHODS
We analyzed genome sequence data for 28 SARS-CoV-2-positive specimens collected from 8 shelters in King County, Washington between March and October, 2020.
RESULTS
We identified at least 12 separate SARS-CoV-2 introduction events into these 8 shelters and estimated that 57% (16 of 28) of the examined cases of SARS-CoV-2 infection were the result of intrashelter transmission. However, we identified just a few SARS-CoV-2 specimens from Washington that were possible descendants of shelter viruses.
CONCLUSIONS
Our data suggest that SARS-CoV-2 spread in shelters is common, but we did not observe evidence of widespread transmission of shelter-related viruses into the general population.

Identifiants

DOI: 10.1093/infdis/jiac021 PMID: 35091746 PMC: PMC8807325
pubmed: 35091746
pii: 6517044
doi: 10.1093/infdis/jiac021
pmc: PMC8807325
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

217-224

Subventions

Organisme : Centers for Disease Control
ID : 75D30120C09322

Informations de copyright

© The Author(s) 2022. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Auteurs

Amanda M Casto (AM)

Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.
Vaccine and Infectious Diseases Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
ORCID: 0000-0001-8332-8578

Julia H Rogers (JH)

Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.

Amy C Link (AC)

Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.

Michael Boeckh (M)

Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.
Vaccine and Infectious Diseases Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Brotman Baty Institute for Precision Medicine, Seattle, Washington, USA.

Michael L Jackson (ML)

Kaiser Permanente Washington Health Research Institute, Seattle, Washington, USA.

Timothy M Uyeki (TM)

Influenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Janet A Englund (JA)

Brotman Baty Institute for Precision Medicine, Seattle, Washington, USA.
Seattle Children's Research Institute, Seattle, Washington, USA.

Lea M Starita (LM)

Brotman Baty Institute for Precision Medicine, Seattle, Washington, USA.

Helen Y Chu (HY)

Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.
Brotman Baty Institute for Precision Medicine, Seattle, Washington, USA.

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Classifications MeSH

questionsmedicales.fr › Maladies de l'appareil respiratoire › Infections de l'appareil respiratoire › Pneumopathie infectieuse › Pneumopathie virale › COVID-19 › Phylogenomics of Severe Acute Respiratory...
questionsmedicales.fr › Environnement et santé publique › Environnement › Catastrophes › Abri d'urgence › Phylogenomics of Severe Acute Respiratory...
questionsmedicales.fr › Personnes › Sans-abri › Phylogenomics of Severe Acute Respiratory...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Phylogenomics of Severe Acute Respiratory...
questionsmedicales.fr › Sciences de l'information › Phylogenèse › Phylogenomics of Severe Acute Respiratory...
questionsmedicales.fr › Virus › Virus à ARN › Virus à ARN à brin positif › Nidovirales › Coronaviridae › Coronavirus › Betacoronavirus › Virus du SRAS › SARS-CoV-2 › Phylogenomics of Severe Acute Respiratory...