The HeyL-Aromatase Axis Promotes Cancer Stem Cell Properties by Endogenous Estrogen-Induced Autophagy in Castration-Resistant Prostate Cancer.
CRPC
HeyL
aromatase
autophagy
prostate cancer stem cell
Journal
Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867
Informations de publication
Date de publication:
2021
2021
Historique:
received:
01
10
2021
accepted:
13
12
2021
entrez:
31
1
2022
pubmed:
1
2
2022
medline:
1
2
2022
Statut:
epublish
Résumé
Treatment of patients with castration-resistant prostate cancer (CRPC) remains a major clinical challenge. We previously showed that estrogenic effects contribute to CRPC progression and are primarily caused by the increased endogenous estradiol produced
Identifiants
pubmed: 35096586
doi: 10.3389/fonc.2021.787953
pmc: PMC8789881
doi:
Types de publication
Journal Article
Langues
eng
Pagination
787953Informations de copyright
Copyright © 2022 Lin, Cao, Du, Yang, Shen, Wang, Klocker, Shi and Zhang.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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