Analgesic effect of curcumin topical formulation in knee osteoarthritis patients: a clinical trial.
OA
VAS
WOMAC
curcumin
diclofenac
pain
Journal
Journal of basic and clinical physiology and pharmacology
ISSN: 2191-0286
Titre abrégé: J Basic Clin Physiol Pharmacol
Pays: Germany
ID NLM: 9101750
Informations de publication
Date de publication:
01 Jan 2023
01 Jan 2023
Historique:
received:
23
08
2021
accepted:
28
11
2021
pubmed:
3
2
2022
medline:
27
1
2023
entrez:
2
2
2022
Statut:
epublish
Résumé
The aim of this study was to recognize the efficacy and safety of curcumin ointment on patients with knee osteoarthritis (OA) compare to diclofenac as standard medication. The topical effects of curcumin (10%) and diclofenac (1%) ointments were assessed through the visual analog scale (VAS) and Western Ontario and McMaster Universities Arthritis (WOMAC) index after three times a day administration for two weeks in 60 patients. Desirable effects compared to the pre-treatment period were observed after two weeks of continuous treatment. Based on our results, VAS and WOMAC index were altered after treatment significantly (p<0.0001). Two-week use of curcumin ointment could ameliorate the pain, stiffness and function disability in patients with OA.
Identifiants
pubmed: 35107231
pii: jbcpp-2021-0255
doi: 10.1515/jbcpp-2021-0255
doi:
Substances chimiques
Anti-Inflammatory Agents, Non-Steroidal
0
Curcumin
IT942ZTH98
Diclofenac
144O8QL0L1
Ointments
0
Types de publication
Clinical Trial
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
41-48Informations de copyright
© 2022 Walter de Gruyter GmbH, Berlin/Boston.
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