Resection of Gastric Cancer Remitted Anti-signal Recognition Particle Myopathy.

MRI anti-glutamic acid decarboxylase antibody anti-signal recognition particle myopathy gastric cancer intravenous immunoglobulin, muscle biopsy

Journal

Internal medicine (Tokyo, Japan)
ISSN: 1349-7235
Titre abrégé: Intern Med
Pays: Japan
ID NLM: 9204241

Informations de publication

Date de publication:
15 Aug 2022
Historique:
pubmed: 4 2 2022
medline: 17 8 2022
entrez: 3 2 2022
Statut: ppublish

Résumé

A 72-year-old woman presented with gradually-worsening myalgia and muscle weakness of the proximal lower limbs as well as elevated serum creatine kinase level. Based on a clinicoseropathological examination including a muscle biopsy, she was diagnosed with anti-signal recognition particle (SRP) myopathy. Although the myopathy relapsed two times in two years under oral prednisolone and intravenous immunoglobulin therapy, the myopathy remained in remission for more than three years after resection of gastric cancer. Although the anti-SRP myopathy is not considered to be cancer-associated in general, we should note that some cases of anti-SRP myopathy may be ameliorated with appropriate cancer treatment.

Identifiants

pubmed: 35110495
doi: 10.2169/internalmedicine.9055-21
pmc: PMC9449613
doi:

Substances chimiques

Autoantibodies 0
Immunoglobulins, Intravenous 0
Signal Recognition Particle 0

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2509-2515

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Auteurs

Yoshihide Sehara (Y)

Department of Neurology, Haga Red Cross Hospital, Japan.
Division of Genetic Therapeutics, Center for Molecular Medicine, Jichi Medical University, Japan.

Kyoichiro Tsuchiya (K)

Department of Diabetes and Endocrinology, University of Yamanashi Hospital, Japan.

Ichizo Nishino (I)

Department of Neuromuscular Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry (NCNP), Japan.
Department of Genome Medicine Development, Medical Genome Center, National Center of Neurology and Psychiatry (NCNP), Japan.

Hirotake Sato (H)

Department of Surgery, Haga Red Cross Hospital, Japan.

Yoshihito Ando (Y)

Department of Neurology, Haga Red Cross Hospital, Japan.

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Classifications MeSH