Downregulation of the FTO m


Journal

Nature cancer
ISSN: 2662-1347
Titre abrégé: Nat Cancer
Pays: England
ID NLM: 101761119

Informations de publication

Date de publication:
06 2021
Historique:
received: 12 06 2019
accepted: 17 05 2021
entrez: 5 2 2022
pubmed: 6 2 2022
medline: 12 4 2022
Statut: ppublish

Résumé

Post-transcriptional modifications of RNA constitute an emerging regulatory layer of gene expression. The demethylase fat mass- and obesity-associated protein (FTO), an eraser of N

Identifiants

pubmed: 35121941
doi: 10.1038/s43018-021-00223-7
pii: 10.1038/s43018-021-00223-7
doi:

Substances chimiques

RNA 63231-63-0
FTO protein, mouse EC 1.14.11.-
Alpha-Ketoglutarate-Dependent Dioxygenase FTO EC 1.14.11.33
FTO protein, human EC 1.14.11.33

Banques de données

figshare
['10.6084/m9.figshare.14602932', '10.6084/m9.figshare.14602944', '10.6084/m9.figshare.14602953', '10.6084/m9.figshare.14602965', '10.6084/m9.figshare.14602971', '10.6084/m9.figshare.14602986']

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

611-628

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM058843
Pays : United States

Commentaires et corrections

Type : CommentIn

Informations de copyright

© 2021. The Author(s), under exclusive licence to Springer Nature America, Inc.

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Auteurs

Jana Jeschke (J)

Laboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université Libre de Bruxelles (ULB), Brussels, Belgium.

Evelyne Collignon (E)

Laboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université Libre de Bruxelles (ULB), Brussels, Belgium.

Clémence Al Wardi (C)

Laboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université Libre de Bruxelles (ULB), Brussels, Belgium.

Mohammad Krayem (M)

Laboratory of Oncology and Experimental Surgery, Institut Jules Bordet, ULB, Brussels, Belgium.

Martin Bizet (M)

Laboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université Libre de Bruxelles (ULB), Brussels, Belgium.

Yan Jia (Y)

Laboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université Libre de Bruxelles (ULB), Brussels, Belgium.
Department of Breast Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.

Soizic Garaud (S)

Molecular Immunology Laboratory, Institut Jules Bordet, ULB, Brussels, Belgium.

Zéna Wimana (Z)

Laboratory of Oncology and Experimental Surgery, Institut Jules Bordet, ULB, Brussels, Belgium.
Department of Nuclear Medicine, Institut Jules Bordet, ULB, Brussels, Belgium.

Emilie Calonne (E)

Laboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université Libre de Bruxelles (ULB), Brussels, Belgium.

Bouchra Hassabi (B)

Laboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université Libre de Bruxelles (ULB), Brussels, Belgium.

Renato Morandini (R)

Laboratory of Oncology and Experimental Surgery, Institut Jules Bordet, ULB, Brussels, Belgium.

Rachel Deplus (R)

Laboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université Libre de Bruxelles (ULB), Brussels, Belgium.

Pascale Putmans (P)

Laboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université Libre de Bruxelles (ULB), Brussels, Belgium.

Gaurav Dube (G)

Laboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université Libre de Bruxelles (ULB), Brussels, Belgium.

Nitesh Kumar Singh (NK)

Laboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université Libre de Bruxelles (ULB), Brussels, Belgium.

Alexander Koch (A)

Department of Pathology, Maastricht UMC, Maastricht, the Netherlands.

Kateryna Shostak (K)

Laboratory of Medical Chemistry, GIGA Stem Cells, University of Liège, Liège, Belgium.

Lara Rizzotto (L)

Trace, LKI Leuven Cancer Institute, KU Leuven, Leuven, Belgium.

Robert L Ross (RL)

Rieveschl Laboratories for Mass Spectrometry, Department of Chemistry, University of Cincinnati, Cincinnati, OH, USA.

Christine Desmedt (C)

Breast Cancer Translational Research Laboratory, Institut Jules Bordet, U-CRC, ULB, Brussels, Belgium.

Yacine Bareche (Y)

Breast Cancer Translational Research Laboratory, Institut Jules Bordet, U-CRC, ULB, Brussels, Belgium.

Françoise Rothé (F)

Breast Cancer Translational Research Laboratory, Institut Jules Bordet, U-CRC, ULB, Brussels, Belgium.

Jacqueline Lehmann-Che (J)

Pathophysiology of Breast Cancer Team, Université de Paris, INSERM U976, HIPI, Paris, France.
Breast Disease Unit and Molecular Oncology Unit, AP-HP, Hôpital Saint-Louis, Paris, France.

Martine Duterque-Coquillaud (M)

Université Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, UMR9020-UMR-S 1277, CANTHER, Lille, France.

Xavier Leroy (X)

Université Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, UMR9020-UMR-S 1277, CANTHER, Lille, France.
Department of Pathology, CHU Lille, Université Lille, Lille, France.

Gerben Menschaert (G)

Biobix, Laboratory of Bioinformatics and Computational Genomics, Ghent University, Ghent, Belgium.

Luis Teixeira (L)

Pathophysiology of Breast Cancer Team, Université de Paris, INSERM U976, HIPI, Paris, France.
Breast Disease Unit and Molecular Oncology Unit, AP-HP, Hôpital Saint-Louis, Paris, France.

Mingzhou Guo (M)

Department of Gastroenterology & Hepatology, Chinese PLA General Hospital, Beijing, China.

Patrick A Limbach (PA)

Rieveschl Laboratories for Mass Spectrometry, Department of Chemistry, University of Cincinnati, Cincinnati, OH, USA.

Pierre Close (P)

Laboratory of Cancer Signaling, GIGA Stem Cells, University of Liège, Liège, Belgium.
WELBIO, University of Liège, Liège, Belgium.

Alain Chariot (A)

Laboratory of Medical Chemistry, GIGA Stem Cells, University of Liège, Liège, Belgium.
WELBIO, University of Liège, Liège, Belgium.

Eleonora Leucci (E)

Trace, LKI Leuven Cancer Institute, KU Leuven, Leuven, Belgium.
Laboratory of RNA Cancer Biology, Department of Oncology, LKI, KU Leuven, Leuven, Belgium.

Ghanem Ghanem (G)

Laboratory of Oncology and Experimental Surgery, Institut Jules Bordet, ULB, Brussels, Belgium.

Bi-Feng Yuan (BF)

College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, China.

Karen Willard-Gallo (K)

Molecular Immunology Laboratory, Institut Jules Bordet, ULB, Brussels, Belgium.

Christos Sotiriou (C)

Breast Cancer Translational Research Laboratory, Institut Jules Bordet, U-CRC, ULB, Brussels, Belgium.

Jean-Christophe Marine (JC)

Laboratory for Molecular Cancer Biology, VIB, KU Leuven, Leuven, Belgium.
Laboratory for Molecular Cancer Biology, Department of Oncology, KU Leuven, Leuven, Belgium.

François Fuks (F)

Laboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université Libre de Bruxelles (ULB), Brussels, Belgium. ffuks@ulb.ac.be.
WELBIO, Université Libre de Bruxelles (ULB), Brussels, Belgium. ffuks@ulb.ac.be.

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