Myogenic Vasoconstriction Requires Canonical G
angiotensin II type 1a receptor
arterial smooth muscle
biased ligands
myogenic vasoconstriction
Journal
Journal of the American Heart Association
ISSN: 2047-9980
Titre abrégé: J Am Heart Assoc
Pays: England
ID NLM: 101580524
Informations de publication
Date de publication:
15 02 2022
15 02 2022
Historique:
pubmed:
9
2
2022
medline:
9
4
2022
entrez:
8
2
2022
Statut:
ppublish
Résumé
Background Blood pressure and tissue perfusion are controlled in part by the level of intrinsic (myogenic) arterial tone. However, many of the molecular determinants of this response are unknown. We previously found that mice with targeted disruption of the gene encoding the angiotensin II type 1a receptor (AT1AR) (
Identifiants
pubmed: 35132870
doi: 10.1161/JAHA.121.022070
pmc: PMC9245832
doi:
Substances chimiques
Adaptor Proteins, Signal Transducing
0
Agtrap protein, mouse
0
Receptor, Angiotensin, Type 1
0
beta-Arrestins
0
Angiotensin II
11128-99-7
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e022070Commentaires et corrections
Type : CommentIn
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