Epidemiology of Acute Endophthalmitis after Intraocular Procedures: A National Database Study.
Endophthalmitis
Epidemiology
National database
Journal
Ophthalmology. Retina
ISSN: 2468-6530
Titre abrégé: Ophthalmol Retina
Pays: United States
ID NLM: 101695048
Informations de publication
Date de publication:
06 2022
06 2022
Historique:
received:
11
01
2022
revised:
28
01
2022
accepted:
31
01
2022
pubmed:
9
2
2022
medline:
14
6
2022
entrez:
8
2
2022
Statut:
ppublish
Résumé
To describe the causes of postoperative acute endophthalmitis at the national level longitudinally. Cohort study from 2009 to 2018 in France. Patients diagnosed with acute endophthalmitis after intraocular procedures. The French medical-administrative database was used. Endophthalmitis cases and intraocular procedures were identified based on billing codes in all French hospitals and private practices. The incidence of acute endophthalmitis within 42 days of the procedure. From January 1, 2009, to October 31, 2018, 7522 cases of acute endophthalmitis occurred after 14 438 854 intraocular procedures. Most cases occurred after standalone cataract surgery (4808 cases for 7 316 077 procedures; 63.92%), followed by after intravitreal (IVT) injections (1296 cases for 5 455 631 IVT injections; 17.23%), vitreoretinal surgery (698 for 442 263 procedures; 9.28%), anterior segment surgery (245 cases; 3.26%), combined cataract and vitreoretinal surgery (191 cases; 2.54%), cornea surgery (142 cases; 1.89%), and glaucoma surgery (80 cases; 1.06%). The overall incidence of acute endophthalmitis was 1 per 1920 procedures (0.0521%; 95% confidence interval [CI], 0.0520-0.0522). The surgery with the highest incidence of endophthalmitis was scleral and globe surgery, with an incidence of 0.1827% (95% CI, 0.1757-0.1898), followed by vitreoretinal surgery combined with cataract surgery, with an incidence of 0.1685% (95% CI, 0.1663-0.1706). The incidence of endophthalmitis after IVT injections was stable over the study period, and patients receiving IVT injections were the oldest, aged 75.4 years (standard deviation, 12.0 years; P < 0.001). The onset of endophthalmitis after IVT procedures, i.e, after receiving IVT injections or undergoing vitreoretinal surgery, was earlier than that after the other procedures (P < 0.001). The profile of patients referred for acute endophthalmitis has been evolving over the past decade, with a decrease in the raw number of endophthalmitis cases after cataract surgery as opposed to an increase in the number of patients presenting with endophthalmitis after IVT injections.
Identifiants
pubmed: 35134544
pii: S2468-6530(22)00044-6
doi: 10.1016/j.oret.2022.01.022
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
442-449Commentaires et corrections
Type : CommentIn
Informations de copyright
Copyright © 2022 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.