Hematopoietic Stem Cells Characteristics: From Isolation to Transplantation.
Hematopoietic stem cells
homogeneity
isolation
pluripotency
regenerative medicine
therapeutic approaches
transplantation
Journal
Current stem cell research & therapy
ISSN: 2212-3946
Titre abrégé: Curr Stem Cell Res Ther
Pays: United Arab Emirates
ID NLM: 101272517
Informations de publication
Date de publication:
2022
2022
Historique:
received:
20
09
2021
revised:
05
11
2021
accepted:
19
12
2021
pubmed:
15
2
2022
medline:
19
8
2022
entrez:
14
2
2022
Statut:
ppublish
Résumé
Hematopoietic stem cells (HSCs) have self-renewal as well as pluripotency properties and are responsible for producing all types of blood cells. These cells are generated during embryonic development and transit through various anatomical niches (bone marrow microenvironment). Today, they are easily enriched from some sources, including peripheral blood, bone marrow, and umbilical cord blood (UCB). HSCs have been used for many years to treat a variety of cancers and blood disorders such as various types of leukemia, lymphoma, myelodysplastic, myeloproliferative syndromes, etc. Although almost 50 years have passed since the discovery of stem cells and numerous investigations on cell therapy and regenerative medicine have been made, further studies need to be conducted in this regard. This manuscript review the history, location, evolution, isolation, and therapeutic approaches of HSCs.
Identifiants
pubmed: 35152869
pii: CSCR-EPUB-120838
doi: 10.2174/1574888X17666220211160954
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
407-414Subventions
Organisme : Tabriz University of Medical Sciences, Tabriz, Iran
ID : IR.TBZMED.REC.1398.197, 63634
Informations de copyright
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