Near infrared spectroscopic evaluation of biochemical and crimp properties of knee joint ligaments and patellar tendon.
Journal
PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081
Informations de publication
Date de publication:
2022
2022
Historique:
received:
01
06
2021
accepted:
16
01
2022
entrez:
14
2
2022
pubmed:
15
2
2022
medline:
1
3
2022
Statut:
epublish
Résumé
Knee ligaments and tendons play an important role in stabilizing and controlling the motions of the knee. Injuries to the ligaments can lead to abnormal mechanical loading of the other supporting tissues (e.g., cartilage and meniscus) and even osteoarthritis. While the condition of knee ligaments can be examined during arthroscopic repair procedures, the arthroscopic evaluation suffers from subjectivity and poor repeatability. Near infrared spectroscopy (NIRS) is capable of non-destructively quantifying the composition and structure of collagen-rich connective tissues, such as articular cartilage and meniscus. Despite the similarities, NIRS-based evaluation of ligament composition has not been previously attempted. In this study, ligaments and patellar tendon of ten bovine stifle joints were measured with NIRS, followed by chemical and histological reference analysis. The relationship between the reference properties of the tissue and NIR spectra was investigated using partial least squares regression. NIRS was found to be sensitive towards the water (R2CV = .65) and collagen (R2CV = .57) contents, while elastin, proteoglycans, and the internal crimp structure remained undetectable. As collagen largely determines the mechanical response of ligaments, we conclude that NIRS demonstrates potential for quantitative evaluation of knee ligaments.
Identifiants
pubmed: 35157708
doi: 10.1371/journal.pone.0263280
pii: PONE-D-21-18102
pmc: PMC8843223
doi:
Substances chimiques
Proteoglycans
0
Elastin
9007-58-3
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0263280Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
J Musculoskelet Neuronal Interact. 2005 Mar;5(1):22-34
pubmed: 15788868
Clin Biomech (Bristol, Avon). 1995 Jan;10(1):29-35
pubmed: 11415528
Int Rev Cytol. 2000;196:85-130
pubmed: 10730214
Acta Biomater. 2018 Apr 1;70:281-292
pubmed: 29409868
Sci Rep. 2018 Sep 7;8(1):13409
pubmed: 30194446
Ann Biomed Eng. 2004 Jul;32(7):924-31
pubmed: 15298430
Acta Biomater. 2015 Oct;25:304-12
pubmed: 26162584
Skeletal Radiol. 1996 May;25(4):365-70
pubmed: 8738002
Anal Chim Acta. 2020 Apr 29;1108:1-9
pubmed: 32222230
Ann Biomed Eng. 2013 Nov;41(11):2426-36
pubmed: 23824216
J Biomech. 2013 Feb 22;46(4):813-8
pubmed: 23219277
J Mech Behav Biomed Mater. 2016 Oct;63:443-455
pubmed: 27472764
Data Brief. 2021 Mar 19;36:106976
pubmed: 33869696
Matrix. 1991 Jun;11(3):214-34
pubmed: 1870453
J Mech Behav Biomed Mater. 2020 Apr;104:103639
pubmed: 32174397
J Orthop Res. 2016 Feb;34(2):270-8
pubmed: 26267333
Am J Sports Med. 2010 Dec;38(12):2516-21
pubmed: 20847221
J Orthop Res. 1996 Jul;14(4):518-25
pubmed: 8764859
Osteoarthritis Cartilage. 2006 Feb;14(2):114-9
pubmed: 16242972
Biochem J. 1986 May 15;236(1):1-14
pubmed: 3539097
J Biomech. 1992 Aug;25(8):831-7
pubmed: 1639827
J Orthop Res. 2013 Aug;31(8):1226-33
pubmed: 23553827
Curr Rheumatol Rep. 2014 Oct;16(10):448
pubmed: 25182676
J R Soc Interface. 2021 Jan;18(174):20200737
pubmed: 33499766
BMC Musculoskelet Disord. 2007 May 29;8:47
pubmed: 17535439
J Am Acad Orthop Surg. 2005 May-Jun;13(3):197-207
pubmed: 15938608
J Biomech. 2018 Oct 5;79:31-38
pubmed: 30082085
Osteoarthritis Cartilage. 2019 Aug;27(8):1235-1243
pubmed: 31026649
Am J Sports Med. 1999 Jul-Aug;27(4):444-54
pubmed: 10424213
J Musculoskelet Neuronal Interact. 2004 Jun;4(2):199-201
pubmed: 15615126
Ann Biomed Eng. 2019 Jan;47(1):213-222
pubmed: 30238376
J Anat. 2011 Jun;218(6):600-7
pubmed: 21466551
Knee. 2012 Aug;19(4):493-9
pubmed: 21852139