Monthly Increase in Vitamin D Levels upon Supplementation with 2000 IU/Day in Healthy Volunteers: Result from "Integriamoci", a Pilot Pharmacokinetic Study.


Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
03 Feb 2022
Historique:
received: 24 12 2021
revised: 25 01 2022
accepted: 30 01 2022
entrez: 15 2 2022
pubmed: 16 2 2022
medline: 22 2 2022
Statut: epublish

Résumé

Vitamin D (VD) is a calcium- and phosphate-controlling hormone used to treat bone disorders; yet, several other effects are progressively emerging. VD deficiency is highly prevalent worldwide, with suboptimal exposure to sunlight listed among the leading causes: oral supplementation with either cholecalciferol or calcitriol is used. However, there is a scarcity of clinical studies investigating how quickly VD concentrations can increase after supplementation. In this pilot study, the commercial supplement ImmuD3 (by

Identifiants

pubmed: 35164307
pii: molecules27031042
doi: 10.3390/molecules27031042
pmc: PMC8840528
pii:
doi:

Substances chimiques

Bone Density Conservation Agents 0
Vitamins 0
Cholecalciferol 1C6V77QF41

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Witt Italia S.p.A.
ID : Not applicable

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Auteurs

Valeria Avataneo (V)

Laboratory of Clinical Pharmacology and Pharmacogenetics, Department of Medical Sciences, Amedeo di Savoia Hospital, University of Turin, 10126 Turin, Italy.

Alice Palermiti (A)

Laboratory of Clinical Pharmacology and Pharmacogenetics, Department of Medical Sciences, Amedeo di Savoia Hospital, University of Turin, 10126 Turin, Italy.

Amedeo De Nicolò (A)

Laboratory of Clinical Pharmacology and Pharmacogenetics, Department of Medical Sciences, Amedeo di Savoia Hospital, University of Turin, 10126 Turin, Italy.

Jessica Cusato (J)

Laboratory of Clinical Pharmacology and Pharmacogenetics, Department of Medical Sciences, Amedeo di Savoia Hospital, University of Turin, 10126 Turin, Italy.

Gloria Giussani (G)

Witt Italia S.p.A., 10046 Poirino, Italy.

Andrea Calcagno (A)

Unit of Infectious Diseases, Department of Medical Sciences, University of Turin, 10124 Turin, Italy.

Antonio D'Avolio (A)

Laboratory of Clinical Pharmacology and Pharmacogenetics, Department of Medical Sciences, Amedeo di Savoia Hospital, University of Turin, 10126 Turin, Italy.

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Classifications MeSH