Determination Factors Associated with Immune Responses Towards First Dose Edmonston-Zagreb (EZ) Measles Vaccine in Indonesian Infants.
Age
Breastfeeding
Immune
Measles
Vitamin A
Journal
Medical archives (Sarajevo, Bosnia and Herzegovina)
ISSN: 1986-5961
Titre abrégé: Med Arch
Pays: Bosnia and Herzegovina
ID NLM: 101635337
Informations de publication
Date de publication:
Oct 2021
Oct 2021
Historique:
received:
18
08
2021
accepted:
05
10
2021
entrez:
16
2
2022
pubmed:
17
2
2022
medline:
19
2
2022
Statut:
ppublish
Résumé
Measles outbreaks under high coverage of measles vaccination in Indonesia is gaining a necessary evaluation of factors associated with measles-vaccine immune responses. The purposes of recent study were to evaluate the association of sociodemographic and anthropometric parameters and specific immune responses towards first dose Edmonston-Zagreb (EZ) measles vaccine in Indonesian infants. A total of 35 infants were enrolled in this cohort study. Measles immune responses were followed up at one and six months after vaccination then analyzed for its association with sociodemographic, anthropometric, and nutritional parameters. The plaque-reduction microneutralization assay was conducted to measure the titer of measles specific IgG antibody. The level of CD4 Vitamin A supplementation and breastfeeding were predicted as associated factor for humoral and cellular immune response after one month and six months measles vaccination among Indonesia Infants. Nutritional factor is associated with measles vaccination immune response in Indonesian infants.
Sections du résumé
BACKGROUND
BACKGROUND
Measles outbreaks under high coverage of measles vaccination in Indonesia is gaining a necessary evaluation of factors associated with measles-vaccine immune responses.
OBJCTIVE
OBJECTIVE
The purposes of recent study were to evaluate the association of sociodemographic and anthropometric parameters and specific immune responses towards first dose Edmonston-Zagreb (EZ) measles vaccine in Indonesian infants.
METHODS
METHODS
A total of 35 infants were enrolled in this cohort study. Measles immune responses were followed up at one and six months after vaccination then analyzed for its association with sociodemographic, anthropometric, and nutritional parameters. The plaque-reduction microneutralization assay was conducted to measure the titer of measles specific IgG antibody. The level of CD4
RESULTS
RESULTS
Vitamin A supplementation and breastfeeding were predicted as associated factor for humoral and cellular immune response after one month and six months measles vaccination among Indonesia Infants.
CONCLUSION
CONCLUSIONS
Nutritional factor is associated with measles vaccination immune response in Indonesian infants.
Identifiants
pubmed: 35169353
doi: 10.5455/medarh.2021.75.335-339
pmc: PMC8740659
doi:
Substances chimiques
Antibodies, Viral
0
Measles Vaccine
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
335-339Informations de copyright
© 2021 Teni Nurlatifah, Wisnu Barlianto, Wayan Arsana Wiyasa, Chandra Kusuma, Tita Luthfia Sari, Novilia Sjafri Bachtiar.
Déclaration de conflit d'intérêts
No conflict of interest
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