A unique case of death by MDPHP with no other co-ingestion: a forensic toxicology case.
Autopsy
Lethal intoxication
MDPHP
Synthetic cathinones
Journal
International journal of legal medicine
ISSN: 1437-1596
Titre abrégé: Int J Legal Med
Pays: Germany
ID NLM: 9101456
Informations de publication
Date de publication:
Sep 2022
Sep 2022
Historique:
received:
23
09
2021
accepted:
09
02
2022
pubmed:
17
2
2022
medline:
17
8
2022
entrez:
16
2
2022
Statut:
ppublish
Résumé
Synthetic cathinones are a class of psychoactive drugs that have become, in recent years, of quite common observation in medical and toxicological forensic field. MDPHP (3,4-methylenedioxy-α-pyrrolidinohexanophenone) belongs to this class of substances but lethal acute intoxication caused by this specific substance without other co-ingestions has never been described in literature. We are presenting the unique case of a fatal acute intoxication caused by MDPHP in a 48-year-old man carried to the A&E department of a big Milanese hospital where he suddenly deceased after brief time. Clinical records, autopsy examination, histological findings, and toxicological analysis, assessed via a Q-Exactive Orbitrap with a HPLC system and LC/MS-MS system, are discussed. This case report may represent the first case of this type of intoxication and might help in improving recognition and treatment of these particular cases.
Identifiants
pubmed: 35169902
doi: 10.1007/s00414-022-02799-w
pii: 10.1007/s00414-022-02799-w
pmc: PMC9375735
doi:
Substances chimiques
Psychotropic Drugs
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1291-1296Informations de copyright
© 2022. The Author(s).
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