Iatrogenic constipation in gastrointestinal surgery.


Journal

Journal of visceral surgery
ISSN: 1878-7886
Titre abrégé: J Visc Surg
Pays: France
ID NLM: 101532664

Informations de publication

Date de publication:
03 2022
Historique:
pubmed: 18 2 2022
medline: 5 4 2022
entrez: 17 2 2022
Statut: ppublish

Résumé

Postoperative constipation occurs relatively frequently, and can involve drug-related, surgical and lifestyle and dietary factors. Gastrointestinal motility can be altered by inflammation, surgery, opioid medications, hypnotics, anti-secretory or anesthetic drugs or by functional modifications for which the physiopathology is not well defined. There are a number of laxatives available. These include bulk laxatives, osmotic laxatives and locally acting laxatives such as suppositories and enemas. Stimulant laxatives have a role to play in the short-term management of persistent constipation. 5-HT4 receptor antagonists are recommended in refractory constipation. Other specific therapeutic laxatives can be proposed such as methylnaltrexone in opioid-induced constipation or neostigmine in Ogilvie's syndrome. The prevention and/or early detection of iatrogenic constipation, whether postoperative or not, is essential and the knowledge how to improve patient comfort and reduce the duration of gastrointestinal motor disorders with specific drugs or other means is essential, particularly the postoperative period.

Identifiants

pubmed: 35172956
pii: S1878-7886(21)00208-3
doi: 10.1016/j.jviscsurg.2021.12.003
pii:
doi:

Substances chimiques

Analgesics, Opioid 0
Laxatives 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

S51-S57

Informations de copyright

Copyright © 2021. Published by Elsevier Masson SAS.

Auteurs

L Diebakate-Scordamaglia (L)

AP-HP, Hepato-Gastroenterology and Nutrition, Antoine-Béclère Hospital, Clamart, France.

C S Voican (CS)

AP-HP, Hepato-Gastroenterology and Nutrition, Antoine-Béclère Hospital, Clamart, France; Paris-Saclay University, Inserm U996, Inflammation, Microbiome and Immunosurveillance, 92140 Clamart, France.

G Perlemuter (G)

AP-HP, Hepato-Gastroenterology and Nutrition, Antoine-Béclère Hospital, Clamart, France; Paris-Saclay University, Inserm U996, Inflammation, Microbiome and Immunosurveillance, 92140 Clamart, France. Electronic address: gabriel.perlemuter@aphp.fr.

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Classifications MeSH