Early versus delayed defunctioning ileostomy closure after low anterior resection for rectal cancer: a meta-analysis and trial sequential analysis of safety and functional outcomes.
Early ileostomy closure
Late ileostomy closure
Low anterior resection
Meta-analysis
Rectal cancer
Trial sequential analysis
Journal
International journal of colorectal disease
ISSN: 1432-1262
Titre abrégé: Int J Colorectal Dis
Pays: Germany
ID NLM: 8607899
Informations de publication
Date de publication:
Apr 2022
Apr 2022
Historique:
accepted:
02
02
2022
pubmed:
23
2
2022
medline:
6
4
2022
entrez:
22
2
2022
Statut:
ppublish
Résumé
We performed a systematic review and meta-analysis with trial sequential analysis (TSA) to answer whether early closure of defunctioning ileostomy may be suitable after low anterior resection. MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials were searched, up to October 2021, for RCTs comparing early closure (EC ≤ 30 days) and delayed closure (DC ≥ 60 days) of defunctioning ileostomy. The risk ratio (RR) with 95% CI was calculated for dichotomous variables and the mean difference (MD) with 95% CI for continuous variables. The GRADE methodology was implemented for assessing Quality of Evidence (QoE). TSA was implemented to address the risk of random error associated with sparse data and/or multiple testing. Seven RCTs were included for quantitative synthesis. 599 patients were allocated to either EC (n = 306) or DC (n = 293). EC was associated with a higher rate of wound complications compared to DC (RR 2.56; 95% CI 1.33 to 4.93; P = 0.005; I EC may confer some advantages compared with a DC. However, TSA advocated a cautious interpretation of the results. CRD42021276557.
Identifiants
pubmed: 35190885
doi: 10.1007/s00384-022-04106-w
pii: 10.1007/s00384-022-04106-w
pmc: PMC8860143
doi:
Types de publication
Journal Article
Meta-Analysis
Review
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
737-756Informations de copyright
© 2022. The Author(s).
Références
Hughes DL, Cornish J, Morris C, LARRIS Trial Management Group (2017) Functional outcome following rectal surgery-predisposing factors for low anterior resection syndrome. Int J Colorectal Dis 32:691–697. https://doi.org/10.1007/s00384-017-2765-0
doi: 10.1007/s00384-017-2765-0
pubmed: 28130593
Heald RJ (1995) Total mesorectal excision is optimal surgery for rectal cancer: a Scandinavian consensus. Br J Surg 82:1297–1299. https://doi.org/10.1002/bjs.1800821002
doi: 10.1002/bjs.1800821002
pubmed: 7489148
Podda M, Di Saverio S, Davies RJ, Atzeni J, Balestra F, Virdis F, Reccia I, Jayant K, Agresta F, Pisanu A (2020) Prophylactic intra-abdominal drainage following colorectal anastomoses. A systematic review and meta-analysis of randomised controlled trials. Am J Surg 219:164–174. https://doi.org/10.1016/j.amjsurg.2019.05.006
doi: 10.1016/j.amjsurg.2019.05.006
pubmed: 31138400
Snijders HS, Wouters MW, van Leersum NJ, Kolfschoten NE, Henneman D, de Vries AC, Tollenaar RA, Bonsing BA (2012) Meta-analysis of the risk for anastomotic leakage, the postoperative mortality caused by leakage in relation to the overall postoperative mortality. Eur J Surg Oncol 38:1013–1019. https://doi.org/10.1016/j.ejso.2012.07.111
doi: 10.1016/j.ejso.2012.07.111
pubmed: 22954525
Sparreboom CL, van Groningen JT, Lingsma HF, Wouters MWJM, Menon AG, Kleinrensink GJ, Jeekel J, Lange JF, Audit DC, group, (2018) Different risk factors for early and late colorectal anastomotic leakage in a nationwide audit. Dis Colon Rectum 61:1258–1266. https://doi.org/10.1097/DCR.0000000000001202
doi: 10.1097/DCR.0000000000001202
pubmed: 30239395
Marusch F, Koch A, Schmidt U, Geibetaler S, Dralle H, Saeger HD, Wolff S, Nestler G, Pross M, Gastinger I, Lippert H (2002) Value of a protective stoma in low anterior resections for rectal cancer. Dis Colon Rectum 45:1164–1171. https://doi.org/10.1007/s10350-004-6384-9
doi: 10.1007/s10350-004-6384-9
pubmed: 12352230
Tan WS, Tang CL, Shi L, Eu KW (2009) Meta-analysis of defunctioning stomas in low anterior resection for rectal cancer. Br J Surg 96:462–472. https://doi.org/10.1002/bjs.6594
doi: 10.1002/bjs.6594
pubmed: 19358171
Montedori A, Cirocchi R, Farinella E, Sciannameo F, Abraha I (2010) Covering ileo- or colostomy in anterior resection for rectal carcinoma. Cochrane Database Syst Rev 12(5):CD006878. https://doi.org/10.1002/14651858.CD006878.pub2
Lu ZR, Rajendran N, Lynch AC, Heriot AG, Warrier SK (2016) Anastomotic leaks after restorative resections for rectal cancer compromise cancer outcomes and survival. Dis Colon Rectum 59:236–244. https://doi.org/10.1097/DCR.0000000000000554
doi: 10.1097/DCR.0000000000000554
pubmed: 26855399
Park JS, Choi GS, Kim SH, Kim HR, Kim NK, Lee KY, Kang SB, Kim JY, Lee KY, Kim BC, Bae BN, Son GM, Lee SI, Kang H (2013) Multicenter analysis of risk factors for anastomotic leakage after laparoscopic rectal cancer excision: the Korean laparoscopic colorectal surgery study group. Ann Surg 257:665–671. https://doi.org/10.1097/SLA.0b013e31827b8ed9
doi: 10.1097/SLA.0b013e31827b8ed9
pubmed: 23333881
Rullier E, Laurent C, Garrelon JL, Michel P, Saric J, Parneix M (1998) Risk factors for anastomotic leakage after resection of rectal cancer. Br J Surg 85:338–355. https://doi.org/10.1046/j.1365-2168.1998.00615.x
doi: 10.1046/j.1365-2168.1998.00615.x
Mäkelä JT, Kiviniemi H, Laitinen S (2003) Risk factors for anastomotic leakage after left-sided colorectal resection with rectal anastomosis. Dis Colon Rectum 46:653–660. https://doi.org/10.1007/s10350-004-6627-9
doi: 10.1007/s10350-004-6627-9
pubmed: 12792443
Hallböök O, Matthiessen P, Leinsköld T, Nyström PO, Sjödahl R (2002) Safety of the temporary loop ileostomy. Colorectal Dis 4:361–364. https://doi.org/10.1046/j.1463-1318.2002.00398.x
doi: 10.1046/j.1463-1318.2002.00398.x
pubmed: 12780582
Gessler B, Haglind E, Angenete E (2014) A temporary loop ileostomy affects renal function. Int J Colorectal Dis 29:1131–1135. https://doi.org/10.1007/s00384-014-1949-0
doi: 10.1007/s00384-014-1949-0
pubmed: 25026894
Peltrini R, Imperatore N, Altieri G, Castiglioni S, Di Nuzzo MM, Grimaldi L, D’Ambra M, Lionetti R, Bracale U, Corcione F (2021) Prevention of incisional hernia at the site of stoma closure with different reinforcing mesh types: a systematic review and meta-analysis. Hernia 25:639–648. https://doi.org/10.1007/s10029-021-02393-w
doi: 10.1007/s10029-021-02393-w
pubmed: 33713204
pmcid: 8197707
Beck-Kaltenbach N, Voigt K, Rumstadt B (2011) Renal impairment caused by temporary loop ileostomy. Int J Colorectal Dis 26:623–626. https://doi.org/10.1007/s00384-010-1086-3
doi: 10.1007/s00384-010-1086-3
pubmed: 21184086
Robertson I, Leung E, Hughes D, Spiers M, Donnelly L, Mackenzie I, Macdonald A (2005) Prospective analysis of stoma-related complications. Colorectal Dis 7:279–285. https://doi.org/10.1111/j.1463-1318.2005.00785.x
doi: 10.1111/j.1463-1318.2005.00785.x
pubmed: 15859968
Alves A, Panis Y, Lelong B, Dousset B, Benoist S, Vicaut E (2008) Randomized clinical trial of early versus delayed temporary stoma closure after proctectomy. Br J Surg 95:693–698. https://doi.org/10.1002/bjs.6212
doi: 10.1002/bjs.6212
pubmed: 18446781
Bakx R, Busch OR, van Geldere D, Bemelman WA, Slors JF, van Lanschot JJ (2003) Feasibility of early closure of loop ileostomies: a pilot study. Dis Colon Rectum 46:1680–1684. https://doi.org/10.1007/BF02660775
doi: 10.1007/BF02660775
pubmed: 14668595
Menegaux F, Jordi-Galais P, Turrin N, Chigot JP (2002) Closure of small bowel stomas on postoperative day 10. Eur J Surg 168:713–715. https://doi.org/10.1080/00000000000000008
doi: 10.1080/00000000000000008
pubmed: 15362581
Clausen FB, Dohrn N, Hölmich ER, Klein M, Gögenur I (2021) Safety of early ileostomy closure: a systematic review and meta-analysis of randomised controlled trials. Int J Colorectal Dis 36:203–212. https://doi.org/10.1007/s00384-020-03761-1
doi: 10.1007/s00384-020-03761-1
pubmed: 32970178
Cheng Z, Dong S, Bi D, Wang Y, Dai Y, Zhang X (2021) Early versus late preventive ileostomy closure following colorectal surgery: systematic review and meta-analysis with trial sequential analysis of randomized controlled trials. Dis Colon Rectum 64:128–137. https://doi.org/10.1097/DCR.0000000000001839
doi: 10.1097/DCR.0000000000001839
pubmed: 33306538
Menahem B, Lubrano J, Vallois A, Alves A (2018) Early closure of defunctioning loop ileostomy: is it beneficial for the patient? A meta-analysis. World J Surg 42:3171–3178. https://doi.org/10.1007/s00268-018-4603-0
doi: 10.1007/s00268-018-4603-0
pubmed: 29589116
Ng ZQ, Levitt M, Platell C (2020) The feasibility and safety of early ileostomy reversal: a systematic review and meta-analysis. ANZ J Surg 90:1580–1587. https://doi.org/10.1111/ans.16079
doi: 10.1111/ans.16079
pubmed: 32597018
Wang L, Chen X, Liao C, Wu Q, Luo H, Yi F, Wei Y, Zhang W (2021) Early versus late closure of temporary ileostomy after rectal cancer surgery: a meta-analysis. Surg Today 51:463–471. https://doi.org/10.1007/s00595-020-02115-2
doi: 10.1007/s00595-020-02115-2
pubmed: 32833059
Lasithiotakis K, Aghahoseini A, Alexander D (2016) Is early reversal of defunctioning ileostomy a shorter, easier and less expensive operation? World J Surg 40:1737–1740. https://doi.org/10.1007/s00268-016-3448-7
doi: 10.1007/s00268-016-3448-7
pubmed: 26908242
Danielsen AK, Park J, Jansen JE, Bock D, Skullman S, Wedin A, Marinez AC, Haglind E, Angenete E, Rosenberg J (2017) Early closure of a temporary ileostomy in patients with rectal cancer: a multicenter randomized controlled trial. Ann Surg 265:284–290. https://doi.org/10.1097/SLA.0000000000001829
doi: 10.1097/SLA.0000000000001829
pubmed: 27322187
Gallyamov EA, Agapov MA, Lutsevich OE, Kubyshkin VA, Kakotkin VV, Tolstykh MP (2019) Early ileostomy closure in patients with rectal cancer. Primary results of the randomised controlled multicenter trial. Khirurgiia (Mosk) 6:35–40. English, Russian https://doi.org/10.17116/hirurgia201906135
Kłęk S, Pisarska M, Milian-Ciesielska K, Cegielny T, Choruz R, Sałówka J, Szybinski P, Pędziwiatr M (2018) Early closure of the protective ileostomy after rectal resection should become part of the Enhanced Recovery After Surgery (ERAS) protocol: a randomized, prospective, two-center clinical trial. Wideochir Inne Tech Maloinwazyjne 13:435–441. https://doi.org/10.5114/wiitm.2018.79574
doi: 10.5114/wiitm.2018.79574
pubmed: 30524612
pmcid: 6280077
Elsner AT, Brosi P, Walensi M, Uhlmann M, Egger B, Glaser C, Maurer CA (2021) Closure of temporary ileostomy 2 versus 12 weeks after rectal resection for cancer: a word of caution from a prospective, randomized controlled multicenter trial. Dis Colon Rectum 64:1398–1406. https://doi.org/10.1097/DCR.0000000000002182
doi: 10.1097/DCR.0000000000002182
pubmed: 34343161
pmcid: 8492188
Bausys A, Kuliavas J, Dulskas A, Kryzauskas M, Pauza K, Kilius A, Rudinskaite G, Sangaila E, Bausys R, Stratilatovas E (2019) Early versus standard closure of temporary ileostomy in patients with rectal cancer: a randomised controlled trial. J Surg Oncol 120:294–299. https://doi.org/10.1002/jso.25488
doi: 10.1002/jso.25488
pubmed: 31042015
Balshem H, Helfand M, Schünemann HJ, Oxman AD, Kunz R, Brozek J, Vist GE, Falck-Ytter Y, Meerpohl J, Norris S, Guyatt GH (2011) GRADE guidelines: 3. Rating the quality of evidence. J Clin Epidemiol 64:401–406. https://doi.org/10.1016/j.jclinepi.2010.07.015
doi: 10.1016/j.jclinepi.2010.07.015
pubmed: 21208779
Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hróbjartsson A, Lalu MM, Li T, Loder EW, Mayo-Wilson E, McDonald S, McGuinness LA, Stewart LA, Thomas J, Tricco AC, Welch VA, Whiting P, Moher D (2021) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ 372:n71. https://doi.org/10.1136/bmj.n71
doi: 10.1136/bmj.n71
pubmed: 33782057
pmcid: 8005924
Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors) (2021) Cochrane handbook for systematic reviews of interventions version 6.2 (updated February 2021). Cochrane. Available from www.training.cochrane.org/handbook
Shea BJ, Reeves BC, Wells G, Thuku M, Hamel C, Moran J, Moher D, Tugwell P, Welch V, Kristjansson E, Henry DA (2017) AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both. BMJ 358:j4008. https://doi.org/10.1136/bmj.j4008
doi: 10.1136/bmj.j4008
pubmed: 28935701
pmcid: 5833365
Rahbari NN, Weitz J, Hohenberger W, Heald RJ, Moran B, Ulrich A, Holm T, Wong WD, Tiret E, Moriya Y, Laurberg S, den Dulk M, van de Velde C, Büchler MW (2010) Definition and grading of anastomotic leakage following anterior resection of the rectum: a proposal by the International Study Group of Rectal Cancer. Surgery 147:339–351. https://doi.org/10.1016/j.surg.2009.10.012
doi: 10.1016/j.surg.2009.10.012
pubmed: 20004450
Shabbir J, Britton DC (2010) Stoma complications: a literature overview. Colorectal Dis 12:958–964. https://doi.org/10.1111/j.1463-1318.2009.02006.x
doi: 10.1111/j.1463-1318.2009.02006.x
pubmed: 19604288
Review Manager Web (RevMan Web). Version (1.22.0). The Cochrane Collaboration, (October 2020). Available at https://revman.cochrane.org/
DerSimonian R, Laird N (2015) Meta-analysis in clinical trials revisited. Contemp Clin Trials 45(Pt A):139–145. https://doi.org/10.1016/j.cct.2015.09.002
doi: 10.1016/j.cct.2015.09.002
pubmed: 26343745
pmcid: 4639420
Wetterslev J, Thorlund K, Brok J, Gluud C (2008) Trial sequential analysis may establish when firm evidence is reached in cumulative meta-analysis. J Clin Epidemiol 61:64–75. https://doi.org/10.1016/j.jclinepi.2007.03.013
doi: 10.1016/j.jclinepi.2007.03.013
pubmed: 18083463
O’Brien PC, Fleming TR (1979) A multiple testing procedure for clinical trials. Biometrics 35:549–556
doi: 10.2307/2530245
pubmed: 497341
Thorlund K, Devereaux PJ, Wetterslev J, Guyatt G, Ioannidis JP, Thabane L, Gluud LL, Als-Nielsen B, Gluud C (2009) Can trial sequential monitoring boundaries reduce spurious inferences from meta-analyses? Int J Epidemiol 38:276–286. https://doi.org/10.1093/ije/dyn179
doi: 10.1093/ije/dyn179
pubmed: 18824467
Brok J, Thorlund K, Wetterslev J, Gluud C (2009) Apparently conclusive meta-analyses may be inconclusive–trial sequential analysis adjustment of random error risk due to repetitive testing of accumulating data in apparently conclusive neonatal meta-analyses. Int J Epidemiol 38:287–298. https://doi.org/10.1093/ije/dyn188
doi: 10.1093/ije/dyn188
pubmed: 18824466
Farag S, Rehman S, Sains P, Baig MK, Sajid MS (2017) Early vs delayed closure of loop defunctioning ileostomy in patients undergoing distal colorectal resections: an integrated systematic review and meta-analysis of published randomised controlled trials. Colorectal Dis 19:1050–1057. https://doi.org/10.1111/codi.13922
doi: 10.1111/codi.13922
pubmed: 29028289
Sterne JAC, Savović J, Page MJ, Elbers RG, Blencowe NS, Boutron I, Cates CJ, Cheng HY, Corbett MS, Eldridge SM, Emberson JR, Hernán MA, Hopewell S, Hróbjartsson A, Junqueira DR, Jüni P, Kirkham JJ, Lasserson T, Li T, McAleenan A, Reeves BC, Shepperd S, Shrier I, Stewart LA, Tilling K, White IR, Whiting PF, Higgins JPT (2019) RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ 366:l4898. https://doi.org/10.1136/bmj.l4898
doi: 10.1136/bmj.l4898
pubmed: 31462531
GRADEpro GDT (2020) GRADEpro Guideline Development Tool [Software]. McMaster University, 2020 (developed by Evidence Prime, Inc.). Available from https://gradepro.org/
Schünemann H, Brożek J, Guyatt G, Oxman A, (editors) (2013) GRADE handbook for grading quality of evidence and strength of recommendations. Updated October 2013. The GRADE Working Group. Available from https://guidelinedevelopment.org/handbook
Park J, Danielsen AK, Angenete E, Bock D, Marinez AC, Haglind E, Jansen JE, Skullman S, Wedin A, Rosenberg J (2018) Quality of life in a randomised trial of early closure of temporary ileostomy after rectal resection for cancer (EASY trial). Br J Surg 105:244–251. https://doi.org/10.1002/bjs.10680
doi: 10.1002/bjs.10680
pubmed: 29168881
Park J, Angenete E, Bock D, Correa-Marinez A, Danielsen AK, Gehrman J, Haglind E, Jansen JE, Skullman S, Wedin A, Rosenberg J (2020) Cost analysis in a randomised trial of early closure of a temporary ileostomy after rectal resection for cancer (EASY trial). Surg Endosc 34:69–76. https://doi.org/10.1007/s00464-019-06732-y
doi: 10.1007/s00464-019-06732-y
pubmed: 30911920
Keane C, Park J, Öberg S, Wedin A, Bock D, O’Grady G, Bissett I, Rosenberg J, Angenete E (2019) Functional outcomes from a randomised trial of early closure of temporary ileostomy after rectal excision for cancer. Br J Surg 106:645–652. https://doi.org/10.1002/bjs.11092
doi: 10.1002/bjs.11092
pubmed: 30706439
pmcid: 6590150
Dulskas A, Petrauskas V, Kuliavas J, Bickaite K, Kairys M, Pauza K, Kilius A, Sangaila E, Bausys R, Stratilatovas E (2021) Quality of life and bowel function following early closure of a temporary ileostomy in patients with rectal cancer: a report from a single-center randomized controlled trial. J Clin Med 10:768. https://doi.org/10.3390/jcm10040768
doi: 10.3390/jcm10040768
pubmed: 33671925
pmcid: 7919002
Hozo SP, Djulbegovic B, Hozo I (2005) Estimating the mean and variance from the median, range, and the size of a sample. BMC Med Res Methodol 5:13. https://doi.org/10.1186/1471-2288-5-13
doi: 10.1186/1471-2288-5-13
pubmed: 15840177
pmcid: 1097734
Ferrara F, Parini D, Bondurri A, Veltri M, Barbierato M, Pata F, Cattaneo F, Tafuri A, Forni C, Roveron G, Rizzo G, Multidisciplinary Italian Study group for STOmas (MISSTO) (2019) Italian guidelines for the surgical management of enteral stomas in adults. Tech Coloproctol 23:1037–1056. https://doi.org/10.1007/s10151-019-02099-3
doi: 10.1007/s10151-019-02099-3
Espin Basany E, Solís-Peña A, Pellino G, Kreisler E, Fraccalvieri D, Muinelo-Lorenzo M, Maseda-Díaz O, García-González JM, Santamaría-Olabarrieta M, Codina-Cazador A, Biondo S (2020) Preoperative oral antibiotics and surgical-site infections in colon surgery (ORALEV): a multicentre, single-blind, pragmatic, randomised controlled trial. Lancet Gastroenterol Hepatol 5:729–738. https://doi.org/10.1016/S2468-1253(20)30075-3
doi: 10.1016/S2468-1253(20)30075-3
pubmed: 32325012
Spence RT, Hirpara DH, Doshi S, Quereshy FA, Chadi SA (2021) Anastomotic leak after colorectal surgery: does timing affect failure to rescue? Surg Endosc. https://doi.org/10.1007/s00464-020-08270-4 . Epub ahead of print
Tang CL, Seow-Choen F, Fook-Chong S, Eu KW (2003) Bioresorbable adhesion barrier facilitates early closure of the defunctioning ileostomy after rectal excision: a prospective, randomised trial. Dis Colon Rectum 46:1200–1207. https://doi.org/10.1007/s10350-004-6716-9
doi: 10.1007/s10350-004-6716-9
pubmed: 12972964
Keane C, Fearnhead NS, Bordeianou LG, Christensen P, Basany EE, Laurberg S, Mellgren A, Messick C, Orangio GR, Verjee A, Wing K, Bissett I, LARS International Collaborative Group (2020) International Consensus Definition of Low Anterior Resection Syndrome. Dis Colon Rectum 63:274–284. https://doi.org/10.1097/DCR.0000000000001583
doi: 10.1097/DCR.0000000000001583
Vogel I, Reeves N, Tanis PJ, Bemelman WA, Torkington J, Hompes R, Cornish JA (2021) Impact of a defunctioning ileostomy and time to stoma closure on bowel function after low anterior resection for rectal cancer: a systematic review and meta-analysis. Tech Coloproctol 25:751–760. https://doi.org/10.1007/s10151-021-02436-5
doi: 10.1007/s10151-021-02436-5
pubmed: 33792822
pmcid: 8187190
Coimbra R, Edwards S, Kurihara H, Bass GA, Balogh ZJ, Tilsed J, Faccincani R, Carlucci M, Martínez Casas I, Gaarder C, Tabuenca A, Coimbra BC, Marzi I (2020) European Society of Trauma and Emergency Surgery (ESTES) recommendations for trauma and emergency surgery preparation during times of COVID-19 infection. Eur J Trauma Emerg Surg 46:505–510. https://doi.org/10.1007/s00068-020-01364-7
doi: 10.1007/s00068-020-01364-7
pubmed: 32303798
Francis N, Dort J, Cho E, Feldman L, Keller D, Lim R, Mikami D, Phillips E, Spaniolas K, Tsuda S, Wasco K, Arulampalam T, Sheraz M, Morales S, Pietrabissa A, Asbun H, Pryor A (2020) SAGES and EAES recommendations for minimally invasive surgery during COVID-19 pandemic. Surg Endosc 34:2327–2331. https://doi.org/10.1007/s00464-020-07565-w
doi: 10.1007/s00464-020-07565-w
pubmed: 32323016
Zenger S, Gurbuz B, Can U, Balik E, Yalti T, Bugra D (2021) Comparative study between ghost ileostomy and defunctioning ileostomy in terms of morbidity and cost-effectiveness in low anterior resection for rectal cancer. Langenbecks Arch Surg 406:339–347. https://doi.org/10.1007/s00423-021-02089-w
doi: 10.1007/s00423-021-02089-w
pubmed: 33537875
Morks AN, Ploeg RJ, Sijbrand Hofker H, Wiggers T, Havenga K (2013) Late anastomotic leakage in colorectal surgery: a significant problem. Colorectal Dis 15:e271–e275. https://doi.org/10.1111/codi.12167
doi: 10.1111/codi.12167
pubmed: 23398601
Clinical Outcomes of Surgical Therapy Study Group, Nelson H, Sargent DJ, Wieand HS, Fleshman J, Anvari M, Stryker SJ, Beart RW Jr, Hellinger M, Flanagan R Jr, Peters W, Ota D (2004) A comparison of laparoscopically assisted and open colectomy for colon cancer. N Engl J Med 350:2050–2059. https://doi.org/10.1056/NEJMoa032651
doi: 10.1056/NEJMoa032651
Lacy AM, Delgado S, Castells A, Prins HA, Arroyo V, Ibarzabal A, Pique JM (2008) The long-term results of a randomised clinical trial of laparoscopy-assisted versus open surgery for colon cancer. Ann Surg 248:1–7. https://doi.org/10.1097/SLA.0b013e31816a9d65
doi: 10.1097/SLA.0b013e31816a9d65
pubmed: 18580199
Colon Cancer Laparoscopic or Open Resection Study Group, Buunen M, Veldkamp R, Hop WC, Kuhry E, Jeekel J, Haglind E, Påhlman L, Cuesta MA, Msika S, Morino M, Lacy A, Bonjer HJ (2009) Survival after laparoscopic surgery versus open surgery for colon cancer: long-term outcome of a randomised clinical trial. Lancet Oncol 10:44–52. https://doi.org/10.1016/S1470-2045(08)70310-3
doi: 10.1016/S1470-2045(08)70310-3
pubmed: 19071061
Guillou PJ, Quirke P, Thorpe H, Walker J, Jayne DG, Smith AM, Heath RM, Brown JM, MRC CLASICC trial group (2005) Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trial. Lancet 365:1718–1726. https://doi.org/10.1016/S0140-6736(05)66545-2
doi: 10.1016/S0140-6736(05)66545-2
pubmed: 15894098
Fleshman J, Branda M, Sargent DJ, Boller AM, George V, Abbas M, Peters WR Jr, Maun D, Chang G, Herline A, Fichera A, Mutch M, Wexner S, Whiteford M, Marks J, Birnbaum E, Margolin D, Larson D, Marcello P, Posner M, Read T, Monson J, Wren SM, Pisters PW, Nelson H (2015) Effect of laparoscopic-assisted resection vs open resection of stage II or III rectal cancer on pathologic outcomes: the ACOSOG Z6051 randomized clinical trial. JAMA 314:1346–1355. https://doi.org/10.1001/jama.2015.10529
doi: 10.1001/jama.2015.10529
pubmed: 26441179
pmcid: 5140087
Zhou ZG, Hu M, Li Y, Lei WZ, Yu YY, Cheng Z, Li L, Shu Y, Wang TC (2004) Laparoscopic versus open total mesorectal excision with anal sphincter preservation for low rectal cancer. Surg Endosc 18:1211–1215. https://doi.org/10.1007/s00464-003-9170-1
doi: 10.1007/s00464-003-9170-1
pubmed: 15457380
Jayne D, Pigazzi A, Marshall H, Croft J, Corrigan N, Copeland J, Quirke P, West N, Rautio T, Thomassen N, Tilney H, Gudgeon M, Bianchi PP, Edlin R, Hulme C, Brown J (2017) Effect of robotic-assisted vs conventional laparoscopic surgery on risk of conversion to open laparotomy among patients undergoing resection for rectal cancer: the ROLARR randomized clinical trial. JAMA 318:1569–1580. https://doi.org/10.1001/jama.2017.7219
doi: 10.1001/jama.2017.7219
pubmed: 29067426
pmcid: 5818805